Glial Neurobiology

Author : Alexei Verkhratsky
Publisher : John Wiley & Sons
ISBN 13 : 9780470513071
Total Pages : 230 pages
Book Rating : 4.71/5 ( download)

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Download or read book Glial Neurobiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

Author : Alexei Verkhratsky
Publisher : Wiley
ISBN 13 : 9780470015643
Total Pages : 230 pages
Book Rating : 4.40/5 ( download)

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Download or read book Glial Neurobiology written by Alexei Verkhratsky and published by Wiley. This book was released on 2007-09-04 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

Author : Andrew Koob
Publisher : FT Press
ISBN 13 : 0137151713
Total Pages : 193 pages
Book Rating : 4.14/5 ( download)

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Download or read book The Root of Thought written by Andrew Koob and published by FT Press. This book was released on 2009 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the Other 90% of Your Brain Learn about brain science breakthroughs that might hold the key to intelligence, creativity, and imagination. Discover amazing cells that keep your brain growing, adapting, and healing. Preview possible breakthroughs for brain cancer, brain trauma, Alzheimer's, Parkinson's, and even schizophrenia. If you know anything about brains, you've heard of neurons. Those are the cells that have long been seen as central to virtually everything your brain thinks, feels, and does. But neurons represent only 10% of your brain cells. What does the other 90% do? Until recently, scientists didn't have a clue. Now, they're discovering the real function of those long-neglected glial cells-and the story is nothing short of amazing. In "The Root of Thought," brain scientist Andrew Koob reveals that story. You'll learn what glial cells are, how they function, and how they might help explain everything from intelligence and creativity to imagination and dreams. Then, Koob reveals the tantalizing clues about glial cells that could eventually lead to cures for brain injury, psychiatric disorders, Alzheimer's, Parkinson's, Lou Gehrig's disease, and even brain cancer. Chapter 1: Cities and Highways 1 Chapter 2: Dust Settles on the Battlefield 5 Chapter 3: I Sing the Body Electric 15 Chapter 4: Meet the Astrocyte 29 Chapter 5: Riding the Calcium Wave 41 Chapter 6: Hey Neuron, It's Me, Glia 55 Chapter 7: Developing Relationships 65 Chapter 8: The Time Machine 77 Chapter 9: Sing a New Song 89 Chapter 10: Albert Einstein's Abundant Astrocytes 99 Chapter 11: I Dream of Glia 111 Chapter 12: Gliadegenerative Disease 121 Chapter 13: Don't Insult Me 133 Chapter 14: The Seething Breeding Glioma 145 Chapter 15: Cities and Highways Revisited 155 Acknowledgments 159 About the Author 161 Index 163

Author : Kristjan R. Jessen
Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.38/5 ( download)

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Download or read book Glial Cell Development written by Kristjan R. Jessen and published by . This book was released on 2001 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The majority of cells in the nervous system are glial cells. During de velopment, these cells provide growth factors that stimulate the proli feration, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabo lic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axona l regrowth and recovery of lost function. This book provides a compreh ensive, state-of-the-art overview of research into the development, fu nction and malfunction of glial cells. It offers a compelling insight into how basic research throws light onto diseases and disorders and p oints the way towards treatments. Teams of internationally renowned ex perts, all active in research, have contributed chapters.

Author : Rommy von Bernhardi
Publisher : Springer
ISBN 13 : 3319407643
Total Pages : 348 pages
Book Rating : 4.47/5 ( download)

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Download or read book Glial Cells in Health and Disease of the CNS written by Rommy von Bernhardi and published by Springer. This book was released on 2016-10-06 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.

Author : Glenn I. Hatton
Publisher : Springer Science & Business Media
ISBN 13 : 1402079370
Total Pages : 442 pages
Book Rating : 4.75/5 ( download)

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Download or read book Glial ⇔ Neuronal Signaling written by Glenn I. Hatton and published by Springer Science & Business Media. This book was released on 2004-05-31 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial Neuronal Signaling fills a need for a monograph/textbook to be used in advanced courses or graduate seminars aimed at exploring glial-neuronal interactions. Even experts in the field will find useful the authoritative summaries of evidence on ion channels and transporters in glia, genes involved in signaling during development, metabolic cross talk and cooperation between astrocytes and neurons, to mention but a few of the timely summaries of a wide range of glial-neuronal interactions. The chapters are written by the top researchers in the field of glial-neuronal signaling, and cover the most current advances in this field. The book will also be of value to the workers in the field of cell biology in general. When we think about the brain we usually think about neurons. Although there are 100 billion neurons in mammalian brain, these cells do not constitute a majority. Quite the contrary, glial cells and other non-neuronal cells are 10-50 times more numerous than neurons. This book is meant to integrate the emerging body of information that has been accumulating, revealing the interactive nature of the brain's two major neural cell types, neurons and glia, in brain function.

Author : Alexei Verkhratsky
Publisher : John Wiley & Sons
ISBN 13 : 1118402057
Total Pages : 473 pages
Book Rating : 4.54/5 ( download)

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Download or read book Glial Physiology and Pathophysiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2013-01-31 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Author : Yves Agid
Publisher : Oxford University Press
ISBN 13 : 0192587013
Total Pages : 161 pages
Book Rating : 4.15/5 ( download)

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Download or read book Glial Man written by Yves Agid and published by Oxford University Press. This book was released on 2020-11-26 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial cells play an essential role in initiating and controlling our behaviours, playing a major role in communication between brain cells. They share certain properties with neurons, including the ability to use information from the environment to formulate behaviors. Understanding these cells is key to explaining human movement, emotion, and thoughts. Moreover, glial cells provide a panoply of new therapeutic targets for the treatment of neuropsychiatric disorders. This book is the 'brain' child of two scientist physicians: Pierre Magistretti, a leading expert in cerebral metabolism and glial cell biology, and Yves Agid, an expert in the treatment of nervous system diseases and a researcher in the field of neurodegenerative diseases. This book provides many examples of the decisive role glial cells play in the functioning of the human brain, as well as in neurological and psychiatric pathologies. The result is a revolution in our understanding of the brain and a beacon of hope in the treatment of neuropsychiatric disorders.

Author : Bernardo Castellano
Publisher : Gulf Professional Publishing
ISBN 13 : 9780444514868
Total Pages : 790 pages
Book Rating : 4.64/5 ( download)

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Download or read book Glial Cell Function (Paperback) written by Bernardo Castellano and published by Gulf Professional Publishing. This book was released on 2003-09-15 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although knowledge of the development and differentiation of glial cells has significantly increased in recent years, there are still many questions unanswered. The first section of the book is devoted to this very active topic and includes contributions on Schwann cells, oligodendrocytes, astroglia and microglia. The second section of the book covers cellular interactions, the role they play on myelination and remyelination, how these interactions take place and the molecules involved. The third section of this volume focuses on the interactions of neurons with glial cells and their role in brain function. Neuron-glia cross talk appears to be fundamental for synaptic transmission and several chapters in this section address this topic. The topic of how glial cells react to brain injury and how they participate in neuroprotection and brain repair is covered in section four of this book. As our knowledge about the molecules involved in the regenerative properties of glia increases, new avenues are open for the use of genetically modified glia with therapeutic purposes. The final section of the book is devoted to therapeutic approaches to tumours, viral and prion infections. Gene therapy is a promising approach for the treatment of gliomas, one of the most devastating forms of cancer. A chapter on prion diseases and microglia addresses a question of tremendous actuality, since prion diseases in cows is at this moment the major veterinary problem in Europe and has created a considerable social alarm.

Author : Michael Aschner
Publisher : CRC Press
ISBN 13 : 9780849347924
Total Pages : 380 pages
Book Rating : 4.20/5 ( download)

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Download or read book The Role of Glia in Neurotoxicity written by Michael Aschner and published by CRC Press. This book was released on 1996-03-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well established that glial cells represent more than mere passive cytoskeletal support elements of the central and peripheral nervous system. A reciprocal relationship exists between neurons and glia that is vital for mutual differentiation, development, and functioning of both cell types. It also has become apparent that perturbations in glial function may lead to deleterious consequences in juxtaposed neurons. It is therefore possible that neuronal damage induced by chemicals or neuropathic disease involves dissociation of glial-neuronal interactions. The Role of Glia in Neurotoxicity brings together experts in the neurosciences to provide a more complete understanding of the effects of chemicals on nervous system function. This book explores potential sites of glial-neuronal interactions both in the central and peripheral nervous system, focusing on potential sites of neurotoxicant actions. Text introduces basic aspects of neuroscience, the first step toward understanding the mechanisms at work in normal physiology. The ways in which these processes are disturbed in pathological conditions are discussed. Distinguished authors examine the functional interactions between glial cells and neurons during development, adulthood, and senescence. The roles of glia in the normal CNS and PNS are described. The book offers specific, in-depth examples of directly (via diffusive and cell surface signals) or indirectly (via effects on the extracellular fluid or the blood-brain barrier) mediated glial neurotoxicity. This reference includes different techniques, conceptual frameworks, and approaches that are currently used in the study of the role of glia in neurotoxicity. This timely review not only presents an excellent overview of the state of the science but also provides direction for future research into the consequences of an altered glial-neuronal unit.