Mechanisms of Environmental Mutagenesis-Carcinogenesis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461538084
Total Pages : 276 pages
Book Rating : 4.80/5 ( download)

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Book Synopsis Mechanisms of Environmental Mutagenesis-Carcinogenesis by : A. Kappas

Download or read book Mechanisms of Environmental Mutagenesis-Carcinogenesis written by A. Kappas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Environmental Mutagenesis

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Author :
Publisher : Academic Press
ISBN 13 : 9780122204326
Total Pages : 0 pages
Book Rating : 4.28/5 ( download)

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Book Synopsis Environmental Mutagenesis by : Consultant Surgeon Robin Phillips, Esq

Download or read book Environmental Mutagenesis written by Consultant Surgeon Robin Phillips, Esq and published by Academic Press. This book was released on 1995-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ-line and somatic mutations are recognized as significant causes of human disease, and so the detection, identification and study of mutagens in the environment is of increasing mutagenesis.Environmental Mutagenesis describes our current knowledge of the molecular mechanisms of mutagenesis and assesses the role of mutagens in cancer and inherited disease. Full details are also provided on all the major in vivo and in vitro methods of mutagenecity testing, including recently developed methods such as fluorescence in situ hybridization (FISH), the use of genetically engineered cells, and transgene technology.This book presents a unique overview of the current status of mutagenecity research and genetics toxicology in the form of reviews by leading researchers in the field. It is essential reading for all with an interest in genetic toxicology and molecular carcinogenesis, including molecular geneticists, genetic counselors and clinicians.

Genetic Toxicology Testing

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Publisher : Academic Press
ISBN 13 : 0128010061
Total Pages : 458 pages
Book Rating : 4.68/5 ( download)

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Book Synopsis Genetic Toxicology Testing by : Ray Proudlock

Download or read book Genetic Toxicology Testing written by Ray Proudlock and published by Academic Press. This book was released on 2016-05-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own. Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology lab Describes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their results Includes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP) Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab

Chemical Consequences

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Publisher : Rutgers University Press
ISBN 13 : 9780813534138
Total Pages : 220 pages
Book Rating : 4.35/5 ( download)

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Book Synopsis Chemical Consequences by : Scott Frickel

Download or read book Chemical Consequences written by Scott Frickel and published by Rutgers University Press. This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hereis the first historical and sociological account of the formation of an interdisciplinary science known as genetic toxicology, and of the scientists' social movement that created it. After research geneticists discovered that synthetic chemicals were capable of changing the genetic structure of living organisms, scientists began to explore how these chemicals affected gene structure and function. In the late 1960s, a small group of biologists became concerned that chemical mutagens represented a serious and possibly global environmental threat. Genetic toxicology is nurtured as much by public culture as by professional practices, reflecting the interplay of genetics research and environmental politics. Drawing on a wealth of resources, Scott Frickel examines the creation of this field through the lens of social movement theory. He reveals how a committed group of scientist-activists transformed chemical mutagens into environmental problems, mobilized existing research networks, recruited scientists and politicians, secured financial resources, and developed new ways of acquiring knowledge. The result is a book that vividly illustrates how science and activism were interwoven to create a discipline that remains a defining feature of environmental health science.

Environmental Mutagenesis, Carcinogenesis, and Plant Biology

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Author :
Publisher : Greenwood
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.9Z/5 ( download)

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Book Synopsis Environmental Mutagenesis, Carcinogenesis, and Plant Biology by : Edward J. Klekowski

Download or read book Environmental Mutagenesis, Carcinogenesis, and Plant Biology written by Edward J. Klekowski and published by Greenwood. This book was released on 1982 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutagenic Effects of Environmental Contaminants

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Publisher : Elsevier
ISBN 13 : 0323160107
Total Pages : 212 pages
Book Rating : 4.00/5 ( download)

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Book Synopsis Mutagenic Effects of Environmental Contaminants by : H.E. Sutton

Download or read book Mutagenic Effects of Environmental Contaminants written by H.E. Sutton and published by Elsevier. This book was released on 2012-12-02 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutagenic Effects of Environmental Contaminants investigates the mutagenic consequences of environmental contaminants, such as pesticides, industrials, food additives, drugs, and biologicals, as well as the possible relationships between mutagenesis and carcinogenesis. It describes the monitoring of chemical mutagens in the environment and the ways that genetic mutations cause disease in humans. Organized into 14 chapters, this volume begins with an overview of the current burden of human genetic disease and the biochemical mechanisms of mutation. It then discusses practical and feasible methods that use a variety of organisms to screen potential mutagenic agents, increased mutation rates in human populations, mutagens that are currently used commercially, and the interrelationships between mutagenicity, carcinogenicity, and teratogenicity. The reader is also introduced to genetic toxicology, detection of chemically induced mutations in experimental animals, and chromosome and somatic mutations in humans. This book is a valuable resource for scientists, policymakers, and administrators of environmental programs.

Environmental Mutagenesis

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Publisher :
ISBN 13 :
Total Pages : 78 pages
Book Rating : 4.12/5 ( download)

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Book Synopsis Environmental Mutagenesis by : Environmental Mutagen Society. Meeting

Download or read book Environmental Mutagenesis written by Environmental Mutagen Society. Meeting and published by . This book was released on 2003 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Program, 1999 Environmental Mutagen Society Meeting

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Publisher :
ISBN 13 :
Total Pages : 83 pages
Book Rating : 4.15/5 ( download)

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Book Synopsis Program, 1999 Environmental Mutagen Society Meeting by : Environmental Mutagen Society. Meeting

Download or read book Program, 1999 Environmental Mutagen Society Meeting written by Environmental Mutagen Society. Meeting and published by . This book was released on 2000 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Trends in Environmental Mutagenesis

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Author :
Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.39/5 ( download)

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Book Synopsis Trends in Environmental Mutagenesis by :

Download or read book Trends in Environmental Mutagenesis written by and published by . This book was released on 1999 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutation, Cancer, and Malformation

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Publisher : Springer Science & Business Media
ISBN 13 : 1461323991
Total Pages : 852 pages
Book Rating : 4.90/5 ( download)

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Book Synopsis Mutation, Cancer, and Malformation by : Ernest H.Y. Chu

Download or read book Mutation, Cancer, and Malformation written by Ernest H.Y. Chu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early 1930s, when I was a graduate student and later a post-doctoral researcher at the National Research Council for the University of Wisconsin at Madison, we had the opportunity to get acquainted with many graduate students from China who were sent to the University for training in modern basic sciences as well as social sciences. The University of Wisconsin continues to graduate a large number of Chinese students. Economic conditions in the 1930s were very precarious for the United States and other parts of the world. Many of us students grew closer together because we were living on similarly tight budgets. As a matter of fact, we subleased a part of our apartment in Madison to some Chinese graduate students. This was a very nice opportunity for us to learn about the scientific and cultural back ground of our Chinese friends. Many of them came from the interior of China and had had very little opportunity to become acquainted with people from a western culture. Living with these students was a very pleasant and educational experience which gave us a good pic ture of the cultural life and educational system of China at that time--an intimate picture that one normally would not see without travelling in that country.