Biochemical Aspects Of Copper

Author : Maria C. Linder
Publisher : Springer Science & Business Media
ISBN 13 : 1475794320
Total Pages : 534 pages
Book Rating : 4.28/5 ( download)

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Download or read book Biochemistry of Copper written by Maria C. Linder and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Copper has long been known as essential to living systems, in part through its fundamental role in electron transport and respiration. Over the years into the present, its involvement in an ever increasing number of processes in all kinds of organisms has become apparent, and new and exciting vistas of its roles in such areas as the central nervous system, and in humoral functions, are appearing on the horizon. Although the biochemistry of this element has not been studied nearly as much as that of many others, a for midable amount of work has been carried out. It has thus been a challenge to produce a summary of what has been found that provides both breadth and depth. My goal has been to try to be as comprehensive as possible, within some limitations. I have tried to provide basic information and basic data that should continue to be useful for a long time. The goal has also been to interpret where we currently stand in our knowledge of the structure, function, regulation, and metabolism of Cu-dependent processes and sub stances, especially proteins. Thus, I have tried to make this a source book for historic as well as current information on all aspects of copper bio chemistry, and a summary of our current knowledge of copper-dependent proteins and processes. Most of the research on copper has been carried out on vertebrates, especially mammals. This has played a role in the organization of the book.

Author : Charles Archibald Owen
Publisher : William Andrew
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.88/5 ( download)

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Download or read book Biochemical Aspects of Copper written by Charles Archibald Owen and published by William Andrew. This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: An authoritative reference text reviews the current body of knowledge concerning the isolation, characterization, and biochemical function of in vivo copper-containing species as related to copper metabolism and in vivo copper complexes for clinical biochemists and nutrition researchers. The material is organized among 3 principal categories: copper proteins and other copper-containing compounds (identified copper proteins (including enzymes) ill- defined copper proteins, possible copper enzymes, and copper porphyrins and other complexes), with references given for each of the 35 proteins and other compounds covered; the chemistry, isolation, function, assay, metabolism, and therapeutic use of ceruloplasmin, including deficiency and excess disorders; and the related topics of copper-protein binding and copper transport. (wz).

Author : Charles Archibald Owen
Publisher : William Andrew
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.14/5 ( download)

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Download or read book Physiological Aspects of Copper written by Charles Archibald Owen and published by William Andrew. This book was released on 1982 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309172209
Total Pages : 161 pages
Book Rating : 4.02/5 ( download)

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Download or read book Copper in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2000-04-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The safety of the nation's drinking water must be maintained to ensure the health of the public. The U.S. Environmental Protection Agency (EPA) is responsible for regulating the levels of substances in the drinking water supply. Copper can leach into drinking water from the pipes in the distribution system, and the allowable levels are regulated by the EPA. The regulation of copper, however, is complicated by the fact that it is both necessary to the normal functioning of the body and toxic to the body at too high a level. The National Research Council was requested to form a committee to review the scientific validity of the EPA's maximum contaminant level goal for copper in drinking water. Copper in Drinking Water outlines the findings of the committee's review. The book provides a review of the toxicity of copper as well as a discussion of the essential nature of this metal. The risks posed by both short-term and long-term exposure to copper are characterized, and the implications for public health are discussed. This book is a valuable reference for individuals involved in the regulation of water supplies and individuals interested in issues surrounding this metal.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309072793
Total Pages : 804 pages
Book Rating : 4.94/5 ( download)

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Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Author : David Evered
Publisher : John Wiley & Sons
ISBN 13 : 0470718307
Total Pages : 192 pages
Book Rating : 4.08/5 ( download)

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Download or read book Biological Roles of Copper written by David Evered and published by John Wiley & Sons. This book was released on 2009-09-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Author : Arturo Leone
Publisher : Springer Science & Business Media
ISBN 13 : 1461548594
Total Pages : 276 pages
Book Rating : 4.91/5 ( download)

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Download or read book Copper Transport and Its Disorders written by Arturo Leone and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of presentations at the first meeting devoted to the mo lecular and cellular biology of copper transport. When we first considered the possible program for the meeting, we felt that a forum to integrate the recent advances in molecular understanding of copper transport with the older knowledge of copper metabolism was needed. In addition we wished to have a strong emphasis on the diseases of copper includ ing the genetic diseases, Menkes and Wilson, and other possible health aspects of this met al seen from a molecular perspective. Overall we were very happy with the success of the meeting, and most participants were very enthusiastic. Unfortunately we were not able to obtain manuscripts from every contributor, but the selection in this book covers most of the topics discussed. The history of biological research into copper dates from the latter half of the last century when the presence of copper as a component of living systems was first noted, but it was not until the 1920s that the essential role of copper was first recognized. l. S. McHargue found that plants and animals needed copper for optimal growth and health and proposed that copper was needed for life (McHargue, 1925). Other groups soon confirmed these observations in plants. In animals the requirement of copper for hematopoiesis was discovered in 1928 (Hart et aI.

Author : Charles Archibald Owen
Publisher : William Andrew
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.04/5 ( download)

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Download or read book Copper Deficiency and Toxicity written by Charles Archibald Owen and published by William Andrew. This book was released on 1981 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: A reference text for biochemical and clinical researchers reviews current knowledge of clinical and biochemical aspects of copper (Cu) deficiency and toxicity. Topics include: observations of acquired Cu deficiency in animal species; Cu deficiency arising from in vivo Cu complexing agents; inherited Cu deficiency (Menkes' desease and animal models thereof); acquired Cu toxicity in microorganisms, plants, and animals; human acquired Cu toxicity (intentional and unintentional Cu toxicity; medicalaspects of human Cu toxicity; toxicity treatment; non-Wilsonian liver disease); and beneficial applications ofCu toxicity and Cu therapy (e.g., antitumor therapy; treating infectious diseases; anti-inflammatory applications; Cu intrauterine devices; Cu supplementation. (wz).

Author : C Kies
Publisher : Springer Science & Business Media
ISBN 13 : 1461305373
Total Pages : 309 pages
Book Rating : 4.78/5 ( download)

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Download or read book Copper Bioavailability and Metabolism written by C Kies and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition is truly a science of the 20th century. That physiological disabilities could be caused by a lack of exogenous substances which could be supplied by foods is a concept of relatively recent origins. It is not surprising, therefore, that, until the last few years, much of nutritional science research was tied to: 1) establishing a cause and effect relationship between a physiological problem and its cure/prevention by a chemical substance in food; 2) quantifying the amount of the substance (nutrient) needed to prevent deficiency symptoms; and 3) quantifying the amounts of nutrients found in various food substances. That a nutrient might be present in apparently adequate amounts in foods consumed by an individual but could not be fully utilized because of the concurrent consumption of anti-nutrients has been recognized as being an important problem as, for example, iodine-deficiency goiters resulting from consumption of gOitrigens. That less specific, less dramatic interactions among nutrients and among nutrients and other food components might enhance or inhibit the absorption of nutrients from the intestines or of the metabolism of nutrients within the body is an area of current concern.

Author : Rene Lontie
Publisher : CRC Press
ISBN 13 : 1351087797
Total Pages : 460 pages
Book Rating : 4.97/5 ( download)

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Download or read book Copper Proteins and Copper Enzymes written by Rene Lontie and published by CRC Press. This book was released on 2018-02-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes of Copper Proteins and Copper Enzymes are intended to describe the contemporary spectroscopy and other biophysical chemistry now being applied to copper proteins in order to determine the structures of their active sites. Several chapters of the treatise describe the functional understanding which is emerging from the new work. The authors are all major contributors to research progress on copper proteins and the volumes will be found to be definitive and authoritative.