Understanding Breast Cancer Genetics

Author : Barbara T. Zimmerman
Publisher : Univ. Press of Mississippi
ISBN 13 : 1604730447
Total Pages : 128 pages
Book Rating : 4.49/5 ( download)

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Download or read book Understanding Breast Cancer Genetics written by Barbara T. Zimmerman and published by Univ. Press of Mississippi. This book was released on 2009-09-18 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic basis of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included.

Author : Clarissa Foster
Publisher :
ISBN 13 : 9781781611203
Total Pages : 0 pages
Book Rating : 4.03/5 ( download)

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Download or read book Understanding BRCA written by Clarissa Foster and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Do you have a close relative who has died from, or is experiencing, aggressive breast, ovarian or prostate cancer? Have they been tested for the BRCA gene mutation? Have you? At the age of 35 and following the death of her mother from ovarian cancer, Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast and ovarian cancer. She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation, the options available to her to lower her risk and, most importantly, how it would feel to undergo risk-reducing surgery. Finding nothing that answered her needs, she set about reading all the available medical literature and liaising with relevant medical professionals to answer her questions. This book is the result of that research and of the decision she took based on it – to have a bilateral mastectomy and salpingo-oophorectomy. Within the context of her own painful experience of family cancer and of elective surgery, Clarissa explains what the BRCA mutation is, what it signifies, what the individual’s choices are and what the fall out can be in terms of a woman’s body image, identity and sexual functioning."--Publisher's description.

Author : B.A. Ponder
Publisher : Springer Science & Business Media
ISBN 13 : 9401106770
Total Pages : 222 pages
Book Rating : 4.71/5 ( download)

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Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309174562
Total Pages : 150 pages
Book Rating : 4.65/5 ( download)

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Download or read book A Review of the Department of Defense's Program for Breast Cancer Research written by Institute of Medicine and published by National Academies Press. This book was released on 1997-07-31 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to current statistical data, one in eight women will be diagnosed with breast cancer. The five-year survival rate for breast cancer patients has improved in recent years, but the overall mortality rates have changed little. In 1993 Congress allocated $210 million for breast cancer research as part of the Department of Defense budget. An Institute of Medicine (IOM) committee was convened at that time to advise the U.S. Army Medical Research and Development Command on strategies for managing a breast cancer research program. This book evaluates the program's management and achievements to date. Although it is too early to evaluate the program in terms of breakthrough results and new insights produced by the funded projects or investigators, this book documents the process used to select research proposals for funding and analyzes the portfolio of funded projects in terms of their responsiveness to the recommendations and fundamental questions articulated in the 1993 IOM report.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309075505
Total Pages : 34 pages
Book Rating : 4.03/5 ( download)

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Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-06-04 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: X-ray mammography screening is the current mainstay for early breast cancer detection. It has been proven to detect breast cancer at an earlier stage and to reduce the number of women dying from the disease. However, it has a number of limitations. These current limitations in early breast cancer detection technology are driving a surge of new technological developments, from modifications of x-ray mammography such as computer programs that can indicate suspicious areas, to newer methods of detection such as magnetic resonance imaging (MRI) or biochemical tests on breast fluids. To explore the merits and drawbacks of these new breast cancer detection techniques, the Institute of Medicine of the National Academy of Sciences convened a committee of experts. During its year of operation, the committee examined the peer-reviewed literature, consulted with other experts in the field, and held two public workshops. In addition to identifying promising new technologies for early detection, the committee explored potential barriers that might prevent the development of new detection methods and their common usage. Such barriers could include lack of funding from agencies that support research and lack of investment in the commercial sector; complicated, inconsistent, or unpredictable federal regulations; inadequate insurance reimbursement; and limited access to or unacceptability of breast cancer detection technology for women and their doctors. Based on the findings of their study, the committee prepared a report entitled Mammography and Beyond: Developing Technology for Early Detection of Breast Cancer, which was published in the spring of 2001. This is a non-technical summary of that report.

Author : Dina Roth Port
Publisher : Penguin
ISBN 13 : 110144391X
Total Pages : 240 pages
Book Rating : 4.10/5 ( download)

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Download or read book Previvors written by Dina Roth Port and published by Penguin. This book was released on 2010-10-05 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first guide to all surgical and nonsurgical options for women with a high risk for breast cancer. Advances in genetic testing and risk assessment have changed the face of medicine, but with them has come a Pandora's box of dilemmas. Imagine discovering you had a significant risk for developing breast cancer. What would you do? Through the incredible true stories of five young friends, as well as interviews with more than seventy top breast cancer experts, health writer Dina Roth Port addresses the universal questions of women everywhere who have watched family members suffer from the disease and wondered, "Am I next?" Full of practical information, Previvors is the first comprehensive book to guide women through the difficult process of determining their risk, weighing the options, and coping with the emotions of deciding to undergo surgery. Readers will learn: •The pros and cons of getting tested for the BRCA gene •How to decide between surgical or nonsurgical options •The latest research in breast cancer surveillance •The advanced new world of breast reconstruction •How to overcome body image and sex issues post-surgery, and more From navigating health insurance coverage to finding the right medical team, Previvors is an invaluable resource for women facing decisions about their risk and future health. Watch a Video

Author : Kathy Steligo
Publisher : JHU Press
ISBN 13 : 1421444259
Total Pages : 496 pages
Book Rating : 4.53/5 ( download)

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Download or read book Living with Hereditary Cancer Risk written by Kathy Steligo and published by JHU Press. This book was released on 2022-09-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides a comprehensive overview of hereditary cancer for a general audience, with coverage of the genetic tests available for detecting risk for heritable cancers as well as options for medical and surgical treatment"--

Author : Piri Welcsh
Publisher : Springer Science & Business Media
ISBN 13 : 1441904778
Total Pages : 346 pages
Book Rating : 4.75/5 ( download)

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Download or read book The Role of Genetics in Breast and Reproductive Cancers written by Piri Welcsh and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.

Author : Kenneth D. Miller
Publisher : JHU Press
ISBN 13 : 142144190X
Total Pages : 457 pages
Book Rating : 4.00/5 ( download)

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Download or read book The Breast Cancer Book written by Kenneth D. Miller and published by JHU Press. This book was released on 2021-09-28 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Providing comprehensive, current, and reliable information on breast cancer, this book, written by an experienced oncologist, a surgeon, and a breast cancer survivor, informs and inspires readers, wherever they are in the breast cancer experience. Patient stories, essays from medical specialists, and illustrations add clarity and insight"--

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309169240
Total Pages : 160 pages
Book Rating : 4.40/5 ( download)

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Download or read book Cancer and the Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2002-08-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.