Tumor Immune Microenvironment In Cancer Progression And Cancer Therapy

Author : Pawel Kalinski
Publisher : Springer
ISBN 13 : 331967577X
Total Pages : 271 pages
Book Rating : 4.70/5 ( download)

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Download or read book Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy written by Pawel Kalinski and published by Springer. This book was released on 2017-12-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.

Author : Ana Karina de Oliveira
Publisher : Frontiers Media SA
ISBN 13 : 283250132X
Total Pages : 309 pages
Book Rating : 4.20/5 ( download)

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Download or read book Tumor Microenvironment (TME) and Tumor Immune Microenvironment (TIME): New Perspectives for Prognosis and Therapy written by Ana Karina de Oliveira and published by Frontiers Media SA. This book was released on 2022-09-30 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Xu Wang
Publisher : Frontiers Media SA
ISBN 13 : 2889747549
Total Pages : 448 pages
Book Rating : 4.42/5 ( download)

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Download or read book Inflammatory Tumor Immune Microenvironment: Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis written by Xu Wang and published by Frontiers Media SA. This book was released on 2022-03-25 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Shoaquan Zheng
Publisher : Frontiers Media SA
ISBN 13 : 2832536557
Total Pages : 537 pages
Book Rating : 4.51/5 ( download)

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Download or read book Tumor Microenvironment and Cancer Therapy written by Shoaquan Zheng and published by Frontiers Media SA. This book was released on 2023-10-17 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well established that the tumor microenvironment(TME) plays a pivotal role in tumor initiation, progression and therapeutic resistance by creating a dynamic interaction with cancer cells. TME is comprised of extracellular matrix (ECM), growth factors, nutrients, blood and lymphatic vessels, and non-cancer stromal cells, which serve as a sustained niche for cancer cells to proliferate and metastasize. Notably, various cellular components in TME, including endothelial cells, fibroblasts, pericytes, adipocytes, immune cells, cancer stem cells, and vasculature, could promote tumor’s immune evasion and growth.

Author : Salem Chouaib
Publisher : Frontiers Media SA
ISBN 13 : 2889638170
Total Pages : 196 pages
Book Rating : 4.78/5 ( download)

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Download or read book Targeting the Tumor Microenvironment for a More Effective and Efficient Cancer Immunotherapy written by Salem Chouaib and published by Frontiers Media SA. This book was released on 2020-07-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Michael R Shurin
Publisher : Springer Science & Business Media
ISBN 13 : 9400762178
Total Pages : 745 pages
Book Rating : 4.76/5 ( download)

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Download or read book The Tumor Immunoenvironment written by Michael R Shurin and published by Springer Science & Business Media. This book was released on 2013-03-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of multidirectional immunological responses at the tumor site allows forming a new concept of The Tumor Immunoenvironment, which is introduced and discussed in the present book with a particular focus on the role of immune cells in controlling the tumor microenvironment at different stages of cancer development. The main goal of this publication is to provide an overview of the current knowledge on the complex and unique role of the immune system, tumor-associated inflammation and tumor-mediated immunomodulation in cancer progression in a way that allows understanding the logistics of cellular and molecular interactions in the tumor lesions.

Author : Xiaoran Yin
Publisher : Frontiers Media SA
ISBN 13 : 2832539505
Total Pages : 149 pages
Book Rating : 4.07/5 ( download)

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Download or read book Tumor Immune Microenvironment Topographies for Prediction and Evaluation: Unlock the Mystery of the Therapeutic Effects and Adverse Events of Tumor Immunotherapy written by Xiaoran Yin and published by Frontiers Media SA. This book was released on 2023-11-24 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Debabrata Banerjee
Publisher : Springer Nature
ISBN 13 : 3030832821
Total Pages : 171 pages
Book Rating : 4.27/5 ( download)

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Download or read book Tumor Microenvironment: Cellular, Metabolic and Immunologic Interactions written by Debabrata Banerjee and published by Springer Nature. This book was released on 2021-12-09 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, the tumor microenvironment has become one of the most important research areas in cancer biology, as cells within the tumor microenvironment, despite being outnumbered by healthy cells, are able to evade surveillance and immune-mediated destruction. While researchers have learned a great deal about the cellular and structural makeup of the tumor microenvironment, there has been a growing understanding of the metabolic interplay between the tumor micronenvironment’s various cellular constituents and how each of them contributes to overall tumor growth and metastases. This new volume will guide researchers, students, oncologists and academics through a rapidly developing and changing field with a thorough understanding of tumor microenvironment biology from a cellular, structural, metabolic, and immunological perspective.

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.68/5 ( download)

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Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Author : Petranel T. Ferrao
Publisher : Frontiers Media SA
ISBN 13 : 288963115X
Total Pages : 186 pages
Book Rating : 4.55/5 ( download)

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Download or read book Cancer Plasticity and the Microenvironment: Implications for Immunity and Therapy Response written by Petranel T. Ferrao and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells can change and adapt, especially within the host environment; a phenomenon known as cancer plasticity. Several factors, including the immune system can influence, and be influenced by, cancer plasticity which in turn can impact upon patient responses to treatment. As such, we currently face several challenges for implementing combination therapies as effective cancer treatment strategies. We have compiled a topic with a number of articles that emphasize the various aspects of cancer plasticity, describing in particular the important role of the tumor microenvironment. As we embark on a new era of precision medicine with multi-modal therapies for improving patient outcomes, this topic highlights some relevant points for consideration that are pertinent to the incorporation and effective use of new treatments as part of cancer treatment regimens, including immune-modulating drugs.