Tick Host Pathogen Interactions

Author : Sarah Irène Bonnet
Publisher : Frontiers Media SA
ISBN 13 : 2889455424
Total Pages : 543 pages
Book Rating : 4.23/5 ( download)

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Download or read book Tick-Host-Pathogen Interactions written by Sarah Irène Bonnet and published by Frontiers Media SA. This book was released on 2018-08-24 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Besides causing direct damage associated with blood feeding and in some cases through the excretion of toxins with their saliva, the main relevance of ticks lies in the wide variety of pathogens that they can transmit, including viruses, bacteria, protozoa and helminths. Owing to socioeconomic and environmental changes, tick distribution is changing with incursions of ticks and tick-borne diseases occurring in different regions of the world when the widespread deployment of chemical acaricides and repellents has led to the selection of resistance in multiple populations of ticks. New approaches that are environmentally sustainable and that provide broad protection against current and future tick-borne pathogen (TBP) are thus urgently needed. Such development, however, requires improved understanding of factors resulting in vector competence and tick-host-pathogen interactions. This Research Topic provides an overview of known molecular tick-host-pathogen interactions for a number of TBPs and highlights how this knowledge can contribute to novel control and prevention strategies for tick-borne diseases.

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.14/5 ( download)

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Download or read book Tick-Host-Pathogen Interactions written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Besides causing direct damage associated with blood feeding and in some cases through the excretion of toxins with their saliva, the main relevance of ticks lies in the wide variety of pathogens that they can transmit, including viruses, bacteria, protozoa and helminths. Owing to socioeconomic and environmental changes, tick distribution is changing with incursions of ticks and tick-borne diseases occurring in different regions of the world when the widespread deployment of chemical acaricides and repellents has led to the selection of resistance in multiple populations of ticks. New approaches that are environmentally sustainable and that provide broad protection against current and future tick-borne pathogen (TBP) are thus urgently needed. Such development, however, requires improved understanding of factors resulting in vector competence and tick-host-pathogen interactions. This Research Topic provides an overview of known molecular tick-host-pathogen interactions for a number of TBPs and highlights how this knowledge can contribute to novel control and prevention strategies for tick-borne diseases.

Author : Frans Jongejan
Publisher : Springer Science & Business Media
ISBN 13 : 9401735263
Total Pages : 315 pages
Book Rating : 4.61/5 ( download)

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Download or read book Ticks and Tick-Borne Pathogens written by Frans Jongejan and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the Proceedings of the 4th International Conference on Ticks and Tick-borne Pathogens (TTP-4), held in Banff, Alberta, Canada, from 21 to 26 July 2002. TTP-4 continues an important tradition established in 1992 at the first Conference in St. Paul, Minnesota, USA, and developed subsequently at the Kruger National Park, South Africa (1995) and the High Tatra Mountains, Slovakia (1999). The 31 papers published in this special issue are divided between six sessions, with a keynote address as an introduction. The first session, which deals with biosystematics, genomics and proteomics of ticks, contains the most recent world list of valid tick names. The papers deal with a broad range of tick-host-pathogen interactions, including remote sensing and mapping of ticks and tick-borne pathogens as well as practical aspects of tick control. It is recommended reading for anyone working on ticks and tick-borne pathogens, which are of increasing medical and veterinary importance worldwide.

Author : Agustín Estrada-Peña
Publisher : Frontiers Media SA
ISBN 13 : 288919406X
Total Pages : 180 pages
Book Rating : 4.63/5 ( download)

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Download or read book The biology and ecology of ticks shape the potential for the transmission of zoonotic pathogens. written by Agustín Estrada-Peña and published by Frontiers Media SA. This book was released on 2015-02-24 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ticks are noticeable by the high diversity of pathogens they can transmit, most of them with implications in human and animal health. Ticks are arachnids, meaning that they do not share the biological and ecological features of the mosquitoes and other parasitic Diptera. The natural foci of tick-borne pathogens may be as large as a continent, or be restricted to small portions of a country, without apparently too many similar features. The life cycle of the ticks involved three developing instars. The precise relationships of ticks and their hosts, the specific seasonal pattern of activity of ticks, and the still poorly known molecular relationships between ticks and the pathogens they can transmit, make these vectors a specially fecund field of research. Importantly, extensive studies on the biological and ecological relationships of ticks and abiotic (climate and vegetation) conditions have revealed the fine-tuning of the ticks and the pathogens they transmit, together with the biological effects of host and the driving features by the climate. The studies on tick-transmitted pathogens have been on the rise in the last years. There is a growing interest in understand the somewhat complex relationships between the landscape, the climate, the vectors and the pathogens, because the concerns of spread, probably driven by subtle changes in climate and man made alterations of the landscape. Studies on Lyme borreliosis are addressing the interesting issue of the relationships between the climate, the tick activity patterns, and the selection of strains according to the reservoir availability. Furthermore, the expanding field of habitat suitability modeling has been applied with different degrees of success to evaluate and quantify the risk of disease transmission. In such exponentially growing field, revisionary books are clearly welcome additions to the bibliographical tools of researchers. It is however necessary the compilation of works devoted to explore the tip of the iceberg in the field of research. In this Research Topic, we wish to summarize and review the studies on ecology, molecular biology, and tick-host-pathogens interactions, provided to resolve the important issues of ticks and pathogens. We want not only the results obtained by newly developed molecular tools, but rigorous reviews of the most recent advances in these issues. This Topic will cover aspects of both human and animal health, with special interest on zoonoses. Aspects of the biology of the ticks, as affecting the transmission of pathogens, are of special interest in this Topic. Studies on ticks of the poorly known family Argasidae, as related to their involvement on pathogen transmission, are especially welcome. We also wish to describe the perspective of the field in the future. Finally, the presentation of ongoing original works is greatly encouraged.

Author : Pat Nuttall
Publisher :
ISBN 13 : 9781789249644
Total Pages : 0 pages
Book Rating : 4.43/5 ( download)

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Download or read book Climate, Ticks and Disease written by Pat Nuttall and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of 77 expert opinions arranged in three sections. Section 1 on "Climate" sets the scene, including predictions of future climate change, how climate change affects ecosystems, and how to model projections of the spatial distribution of ticks and tick-borne infections under different climate change scenarios. Section 2 on "Ticks" focuses on ticks (although tick-borne pathogens creep in) and whether or not changes in climate affect the tick biosphere, from physiology to ecology. Section 3 on "Disease" focuses on the tick-host-pathogen biosphere, ranging from the triangle of tick-host-pathogen molecular interactions to disease ecology in various regions and ecosystems of the world. Each of these three sections ends with a synopsis that aims to give a brief overview of all the expert opinions within the section. The book concludes with Section 4 (Final Synopsis and Future Predictions). This synopsis attempts to summarize evidence provided by the experts of tangible impacts of climate change on ticks and tick-borne infections. In constructing their expert opinions, contributors give their views on what the future might hold. The final synopsis provides a snapshot of their expert thoughts on the future.

Author : Ala E. Tabor
Publisher : Frontiers Media SA
ISBN 13 : 2889740188
Total Pages : 187 pages
Book Rating : 4.85/5 ( download)

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Download or read book Ticks and Host Immunity – New Strategies for Controlling Ticks and Tick-Borne Pathogens written by Ala E. Tabor and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Alan G. Goodman
Publisher : Frontiers Media SA
ISBN 13 : 2889459179
Total Pages : 125 pages
Book Rating : 4.79/5 ( download)

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Download or read book Host-Pathogen Interactions During Arboviral Infections written by Alan G. Goodman and published by Frontiers Media SA. This book was released on 2019-07-19 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arboviruses, or arthropod-borne viruses, such as West Nile virus, Dengue virus, and Zika virus, pose a serious threat to public health worldwide. West Nile virus was introduced to the United States in 1999, and is now endemic, causing over 2,000 domestically acquired cases in the U.S. annually in mammals. Similarly, dengue and Zika viruses are endemic in the Americas and pose novel threats to the human population. Tick-borne viruses such as Powassan virus and Heartland virus are increasing in frequency in the U.S. At this time, there is no commercially available vaccine or therapeutic to treat these viral infections. Because nearly every mammalian case of these virus infections originates from the insect vector, it is imperative that we also understand viral pathogenesis, transmission, and the immune response in insect models as well as pathogenesis and the host responses in infected mammals. The development of methods to block arbovirus transmission from the vector may be effective at ceasing arthropod-to-human infection since the current recommendation to prevent these viral infections is to decrease contact with mosquitoes. Additionally, improving our understanding of epidemiology and ecology will also help develop measures to reduce virus spread. In order to better study mammalian and insect host responses to infection, a number of genetic tools are available, such as fly, mosquito, and tick models, recombinant viruses, mouse models, and bioinformatics tools. The studies described in this eBook will illustrate host responses to infection using mammalian and insect models, identify critical signaling nodes of the innate immune response, and discuss virus transmission from insect to mammal or among infected hosts. Taken together, these studies will elucidate means of decreasing infections in human populations and provide potential targets for future study and therapeutic design.

Author : Ryan Oliver Marino Rego
Publisher : Frontiers Media SA
ISBN 13 : 2889662438
Total Pages : 145 pages
Book Rating : 4.32/5 ( download)

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Download or read book Biological Drivers Of Vector-Pathogen Interactions written by Ryan Oliver Marino Rego and published by Frontiers Media SA. This book was released on 2020-12-14 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Muhammad Abubakar
Publisher : BoD – Books on Demand
ISBN 13 : 1789857651
Total Pages : 184 pages
Book Rating : 4.58/5 ( download)

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Download or read book Ticks and Tick-Borne Pathogens written by Muhammad Abubakar and published by BoD – Books on Demand. This book was released on 2019-03-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.

Author : Tanja Petnicki-Ocwieja
Publisher : Frontiers Media SA
ISBN 13 : 2889195570
Total Pages : 116 pages
Book Rating : 4.72/5 ( download)

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Download or read book Lyme Disease: Recent Advances and Perspectives written by Tanja Petnicki-Ocwieja and published by Frontiers Media SA. This book was released on 2015-08-08 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with novel mechanisms of detection. Because the majority of Lyme disease pathology is due to an over-exuberant immune response, much research in Borrelia burgdorferi pathogenesis has been devoted to understanding the mammalian host response to the bacterium. Immunological studies continue to be an active area of research employing emerging techniques, such as intra-vital imaging. These studies have furthered our understanding of inflammatory processes during long-term infection and provided some surprising insights, such as the continued presence of bacterial products after clearance. The field of Lyme disease has long debated the etiology of long-term inflammation and recent studies in the murine host have shed light on relevant cell types and inflammatory mediators that participate in the pathology of Lyme arthritis. Live imaging and bioluminescent studies have allowed for a novel view of the bacterial life cycle, including the tick mid-gut, tick-to-mammal transmission and dissemination throughout a mouse. A number of tick and bacterial proteins have been shown to participate in the completion of the enzootic cycle. Novel mechanisms of gene regulation are continuously being identified. However, B. burgdorferi lacks many traditional virulence factors, such as toxins or specialized secretion systems. Many genes in the B. burgdorferi genome have no known homolog in other bacteria. Therefore, studies focusing on host-pathogen interactions have therefore been limited by an incomplete understanding of the repertoire of bacterial virulence factors. Questions such as how the pathogen causes disease, colonizes the tick and evades host immune-surveillance have been difficult to address. Genetic studies involving single gene deletions have identified a number of important bacterial proteins, but a large-scale genomics approach to identify virulence factors has not been attempted until recently. The generation of a site-directed mutagenesis library is an important step towards a detailed analysis of the B. burgdorferi genome and pathogenome. Using this library, high-throughput genomic studies, utilizing techniques such as massively parallel sequencing have been promising and could be used to identify novel virulence determinants of disease in the mammalian host or persistence in the tick vector. Continued research on this unique pathogen and its specific interaction with host and vector may have far reaching consequences and provide insights for diverse disciplines including ecology, infectious disease, and immunology. Here, several reviews will discuss the most recent advances and future studies to be undertaken in the field of B. burgdorferi biology.