The Eukaryote Genome In Development And Evolution

Author : John Bernard
Publisher : Springer Science & Business Media
ISBN 13 : 9401159912
Total Pages : 432 pages
Book Rating : 4.13/5 ( download)

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Download or read book The Eukaryote Genome in Development and Evolution written by John Bernard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

Author : John Bernard
Publisher : Springer
ISBN 13 : 9789401159920
Total Pages : 416 pages
Book Rating : 4.20/5 ( download)

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Download or read book The Eukaryote Genome in Development and Evolution written by John Bernard and published by Springer. This book was released on 2012-03-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

Author : Eric H. Davidson
Publisher : Elsevier
ISBN 13 : 9780080455570
Total Pages : 304 pages
Book Rating : 4.73/5 ( download)

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Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams

Author : Robert P Hirt
Publisher : CRC Press
ISBN 13 : 0203508939
Total Pages : 462 pages
Book Rating : 4.30/5 ( download)

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Download or read book Organelles, Genomes and Eukaryote Phylogeny written by Robert P Hirt and published by CRC Press. This book was released on 2004-06-28 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology has spread through every field of biology including systematics and evolution. Researchers can now analyze the genomes of different species relatively quickly, and this is generating a great deal of data and theories about relationships between taxa as well as how they originated and diversified. Org

Author : Rabindra N. Chatterjee
Publisher : Springer Science & Business Media
ISBN 13 : 3662118297
Total Pages : 262 pages
Book Rating : 4.90/5 ( download)

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Download or read book Genome Analysis in Eukaryotes written by Rabindra N. Chatterjee and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decades a breakthrough in the understanding of the mechanisms controlling development has been achieved. This has been possible, in great part, by the use of various experimental approaches. This book focuses on topics concerning some of the processes involved in development, the main emphasis being on the genetic and molecular mechanisms in the evolutionary context. Drosophila is used as an experimental model for the genetic approach to the understanding of behaviour.

Author : Laura A Katz
Publisher : OUP Oxford
ISBN 13 : 0191513857
Total Pages : 256 pages
Book Rating : 4.55/5 ( download)

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Download or read book Genomics and Evolution of Microbial Eukaryotes written by Laura A Katz and published by OUP Oxford. This book was released on 2006-09-07 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics and Evolution of Eukaryotic Microbes synthesizes the rapidly emerging fields of eukaryotic diversity and genome evolution. Eukaryotes (cells with nuclei) evolved as microbes and have existed on Earth for approximately two billion years. The tremendous diversity of eukaryotic microbes (protists) is often overlooked by those who study the macroscopic eukaryotic lineages: plants, animals, and fungi. Yet, eukaryotic microbes are of critical importance to ecosystems, human health, and our desire to understand biodiversity on Earth. By bringing together groundbreaking data from genome studies of diverse eukaryotic microbes, this book elucidates the many novelties among eukaryotic genomes and provides a single resource for otherwise widely dispersed information. Eukaryotic microorganisms impact both our health and our environment. These organisms include some of the deadliest known pathogens such as Plasmodium falciparum, a causative agent of malaria, and Entamoeba histolytica an agent of dysentery. Eukaryotic microbes also play a significant role in environments through their involvement in global biogeochemical cycles. Such roles are perhaps best exemplified by the coccolithophores, including the species Emiliania huxleyi, which can create 'blooms' in the oceans that are visible from outer space (i.e. as large as the state of Alaska). Despite the great importance and breadth of eukaryotic microbes (the vast majority of major ukaryotic lineages are microbial, with plants, animals and fungi representing just three of an estimated 60-200 major lineages), our understanding of their diversity and phylogeny is only now rapidly expanding, in part bolstered by genomic studies. This book presents analyses and interpretations from experts in the field. Recent advances, particularly in DNA sequencing technologies, have made eukaryotic microbes more accessible to genome analyses. Unravelling the wealth of information on eukaryotic genomes will invariably revolutionize our understanding of eukaryotes, including their physiology, systematics, and ecology.

Author : R. N. Chatterjee
Publisher : Springer Verlag
ISBN 13 : 9780387635248
Total Pages : 255 pages
Book Rating : 4.46/5 ( download)

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Download or read book Genome Analysis in Eukaryotes written by R. N. Chatterjee and published by Springer Verlag. This book was released on 1998-01-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Eric H. Davidson
Publisher : Elsevier
ISBN 13 : 9780080525594
Total Pages : 261 pages
Book Rating : 4.98/5 ( download)

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Download or read book Genomic Regulatory Systems written by Eric H. Davidson and published by Elsevier. This book was released on 2001-01-24 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest. The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist. * Contents Include * Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression * Regulation of Direct Cell-Type Specification in Early Development * The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts * Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans

Author : Laura Katz Olson
Publisher : Oxford University Press on Demand
ISBN 13 : 0198569742
Total Pages : 256 pages
Book Rating : 4.49/5 ( download)

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Download or read book Genomics and Evolution of Microbial Eukaryotes written by Laura Katz Olson and published by Oxford University Press on Demand. This book was released on 2006-09-07 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a unique combination of recently-emerged information on eukaryotic microbes, evolution and genomics. Eukaryotes, cells with nuclei, evolved as microbes and have existed on Earth for approximately 2 billion years. Although currently relatively understudied, eukaryotic microorganisms are of critical importance to ecosystems (through their involvement in global biogeochemical cycles), human health (they include some of the deadliest pathogens), and our desire tounderstand global biodiversity. Recent advances, particularly in DNA sequencing technologies, are making eukaryotic microbes more accessible through genome analyses. Insights from these studies are challenging previously held theories of genome evolution, based on studies of a limited number of plants,animals and fungi.

Author : Hervé Tettelin
Publisher : Springer Nature
ISBN 13 : 3030382818
Total Pages : 311 pages
Book Rating : 4.10/5 ( download)

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Download or read book The Pangenome written by Hervé Tettelin and published by Springer Nature. This book was released on 2020-04-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.