The Biology Of Melanomas

Author : Anja K. Bosserhoff
Publisher : Springer
ISBN 13 : 3319413198
Total Pages : 447 pages
Book Rating : 4.98/5 ( download)

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Download or read book Melanoma Development written by Anja K. Bosserhoff and published by Springer. This book was released on 2017-01-20 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Author : Kristian M. Hargadon
Publisher : Humana
ISBN 13 : 9781071612071
Total Pages : 674 pages
Book Rating : 4.77/5 ( download)

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Download or read book Melanoma written by Kristian M. Hargadon and published by Humana. This book was released on 2022-03-26 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive book brings together leading melanoma researchers from across the world and highlights many of the cutting-edge protocols and experimental systems currently being used to investigate questions surrounding this disease. The volume opens with sections on 2D and 3D cell culture-based approaches for studying melanoma biology, and continues with collections of chapters examining various approaches for detecting, isolating, and characterizing circulating melanoma cells, circulating tumor DNA, and exosomes, as well as experimental procedures for studying and detecting melanoma metastasis in both pre-clinical and clinical settings, bioinformatics-based approaches, protocols for quantifying and characterizing immune cell infiltrates in both melanoma tumors and tertiary lymphoid structures, and development and evaluation of therapeutic strategies for melanoma treatment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Melanoma: Methods and Protocols aims to serve basic research scientists and clinicians who bring questions from the clinic into the lab in order to translate observations in the laboratory into improved patient care for this highly malignant form of cancer. Chapter 14 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : U. Reinhold
Publisher : Springer Science & Business Media
ISBN 13 : 3642595375
Total Pages : 284 pages
Book Rating : 4.70/5 ( download)

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Download or read book Minimal Residual Disease in Melanoma written by U. Reinhold and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about diagnostic procedures in melanoma has in creased rapidly within the past few years. Single tumor cells have been identified in normal tissue such as sentinel lymph nodes, as well as in bone marrow, peripheral blood, and other bodily fluids and cells, by molecular technologies. The introduction of polymerase chain reaction-based methods can be regarded as a prototype of this dramatic development towards molecular approaches in new diagnostic procedures. This fact opens up the possibility of clinical use in patients and of influencing treatment strategies. Considerable discrepancies have been described, how ever, in the success rates of these new techniques for the detec tion of minimal residual disease in cancer patients. Despite fav orable results reported by different groups of investigators, it will take several years to define the clinical and pathophysiological relevance of new diagnostic procedures. The 1st International Symposium "Minimal Residual Disease in Melanoma: Biology, Detection and Clinical Relevance of Microme tastases", held in September 1999 in Homburg/Saar, Germany, fo cused on recent developments in this particular area of cancer re search. The purpose of the meeting was to stimulate discussion and exchange of new data and ideas by renowned international scientists. The aim of this volume is to summarize major topics of basic research and clinical investigations presented by invited experts in this fascinating but still. controversial field of melanoma re search.

Author : Myron Gordon
Publisher :
ISBN 13 :
Total Pages : 606 pages
Book Rating : 4.58/5 ( download)

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Download or read book The Biology of Melanomas written by Myron Gordon and published by . This book was released on 1948 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.14/5 ( download)

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Download or read book Cutaneous Melanoma written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Eric H. Bernicker
Publisher : Springer Nature
ISBN 13 : 3030781178
Total Pages : 229 pages
Book Rating : 4.70/5 ( download)

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Download or read book Uveal Melanoma written by Eric H. Bernicker and published by Springer Nature. This book was released on 2021-08-03 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive examination of uveal melanoma, a rare neoplasm that carries a very high mortality and whose natural history makes it fairly unique among adult tumors. Split into three sections, this book explores the basic science behind the disease and inherited genetic syndromes that predispose some patients, as well as the pathology and use of gene expression profiling to determine risk of recurrence. It also focuses on the management of the primary tumor in the eye, including surgical intervention and lesion imaging. Elucidating treatment options for metastatic disease, the book reviews chemotherapy agents and immunotherapy approaches, as well as liver-directed therapies, cellular therapies, and various treatments after primary treatment but before the development of metastases. Uveal Melanoma: Biology and Management is the most up-to-date and comprehensive text devoted solely to this disease and will be useful to medical oncologists, ophthalmologists, radiation therapists, interventional radiologists, pathologists, molecular biologists and immunology researchers, as well as trainees in those fields.

Author : Vincent J. Hearing
Publisher : Springer Science & Business Media
ISBN 13 : 159259994X
Total Pages : 673 pages
Book Rating : 4.43/5 ( download)

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Download or read book From Melanocytes to Melanoma written by Vincent J. Hearing and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Author : Larry Nathanson
Publisher : Springer Science & Business Media
ISBN 13 : 1461317517
Total Pages : 206 pages
Book Rating : 4.17/5 ( download)

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Download or read book Malignant Melanoma: Biology, Diagnosis, and Therapy written by Larry Nathanson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can cer, genitourinary cancer, pediatric oncology, etc.; second, by asking emi nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Author : Meenhard Herlyn
Publisher : R. G. Landes
ISBN 13 :
Total Pages : 116 pages
Book Rating : 4.08/5 ( download)

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Download or read book Molecular and Cellular Biology of Melanoma written by Meenhard Herlyn and published by R. G. Landes. This book was released on 1993 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Charles M. Balch
Publisher : Springer
ISBN 13 : 9783030050689
Total Pages : 0 pages
Book Rating : 4.88/5 ( download)

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Download or read book Cutaneous Melanoma written by Charles M. Balch and published by Springer. This book was released on 2020-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide. Providing the most up-to-date and comprehensive information needed for the clinical management and scientific study of melanoma, Cutaneous Melanoma, 6th edition covers everything from precursors of melanoma to advanced stages of metastatic disease.