Recoding Expansion Of Decoding Rules Enriches Gene Expression

Author : John F. Atkins
Publisher : Springer Science & Business Media
ISBN 13 : 0387893822
Total Pages : 473 pages
Book Rating : 4.22/5 ( download)

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Download or read book Recoding: Expansion of Decoding Rules Enriches Gene Expression written by John F. Atkins and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Author : John F. Atkins
Publisher : Springer
ISBN 13 : 9780387893815
Total Pages : 466 pages
Book Rating : 4.14/5 ( download)

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Download or read book Recoding: Expansion of Decoding Rules Enriches Gene Expression written by John F. Atkins and published by Springer. This book was released on 2009-12-16 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Author : John F. Atkins
Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.58/5 ( download)

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Download or read book Recoding written by John F. Atkins and published by . This book was released on 2010 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic code is dynamic - it, or its readout, can be specifically changed by mRNA signals that modify the behavior of on-board ribosomes. This book describes specific recoding examples to understand the mechanisms and the mRNA signals.

Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1608058964
Total Pages : 300 pages
Book Rating : 4.69/5 ( download)

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Download or read book Frontiers in Clinical Drug Research: HIV written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2015-04-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The first volume of this series features 7 chapters that cover a variety of topics including: -Antiretroviral drug development -HIV-1 genomics -HIV drug targets such as ribosomes and HIV Integrase -HAART associated nephrotoxicity

Author : Eddy C. Agbo
Publisher : BoD – Books on Demand
ISBN 13 : 9535100963
Total Pages : 478 pages
Book Rating : 4.66/5 ( download)

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Download or read book Innovations in Biotechnology written by Eddy C. Agbo and published by BoD – Books on Demand. This book was released on 2012-02-17 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovations in Biotechnology provides an authoritative crystallization of some of the evolving leading-edge biomedical research topics and developments in the field of biotechnology. It is aptly written to integrate emerging basic research topics with their biotechnology applications. It also challenges the reader to appreciate the role of biotechnology in society, addressing clear questions relating to biotech policy and ethics in the context of the research advances. In an era of interdisciplinary collaboration, the book serves an excellent indepth text for a broad range of readers ranging from social scientists to students, researchers and policy makers. Every topic weaves back to the same bottom line: how does this discovery impact society in a positive way?

Author : Daniel L. Kiss
Publisher : Frontiers Media SA
ISBN 13 : 2889765903
Total Pages : 135 pages
Book Rating : 4.04/5 ( download)

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Download or read book mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation written by Daniel L. Kiss and published by Frontiers Media SA. This book was released on 2022-07-25 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Alejandro Ferrando
Publisher : Frontiers Media SA
ISBN 13 : 2889454134
Total Pages : 138 pages
Book Rating : 4.36/5 ( download)

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Download or read book Relevance of Translational Regulation on Plant Growth and Environmental Responses written by Alejandro Ferrando and published by Frontiers Media SA. This book was released on 2018-02-19 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, as sessile organisms, are exposed to a large array of challenging external and internal alterations that may restrict plant growth. These limiting growth conditions activate plant signalling responses which eventually target the protein synthesis machinery to rapidly reprogram plant metabolism to adapt to the new situation. Thus, the control of mRNA translation is one key regulatory step of gene expression and it is an essential molecular mechanism used by plants to bring about impressive growth plasticity. Compared to the vast number of studies aimed to identify plant transcriptional changes upon hormonal or environmental cues, the subsequent steps of mRNA transport, stability, storage, and eventually translational regulation, have been less studied in plants. This lack of knowledge concerns not only the fate of protein-coding transcripts in plants, but also the biogenesis and maturation of rRNAs, tRNAs and the plant translation factors involved. In this eBook we have focused on how internal cues and external signals of either biotic or abiotic origin impact translation to adjust plant growth and development. We have collected altogether ten scientific contributions to extend the knowledge on plant post-transcriptional and translational events that regulate the production of proteins that execute the required cellular functions. We hope that this compilation of original research articles and reviews will provide the readers with a detailed update on the state of knowledge in this field, and also with additional motivation to improve plant growth adaptation to future environmental challenges.

Author : Paola Londei
Publisher : Frontiers Media SA
ISBN 13 : 2889741419
Total Pages : 164 pages
Book Rating : 4.10/5 ( download)

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Download or read book Archaeal Ribosomes: Biogenesis, Structure and Function written by Paola Londei and published by Frontiers Media SA. This book was released on 2022-01-24 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Assen Marintchev
Publisher : Academic Press
ISBN 13 : 0123864976
Total Pages : 267 pages
Book Rating : 4.70/5 ( download)

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Download or read book Fidelity and Quality Control in Gene Expression written by Assen Marintchev and published by Academic Press. This book was released on 2012-01-27 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting. Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting

Author : Chandrasekar Raman
Publisher : Springer
ISBN 13 : 331924244X
Total Pages : 251 pages
Book Rating : 4.46/5 ( download)

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Download or read book Short Views on Insect Genomics and Proteomics written by Chandrasekar Raman and published by Springer. This book was released on 2015-12-10 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entomology is a super science, embracing interdisciplinary approaches in genomics, proteomics, and interdependent fields of biochemistry, physiology, molecular entomology, and biotechnology. An urgent need to manage available resources for the benefit of the planet and humankind has led to remarkable progress since publication of the fruit fly genome in 2000. “Short Views on Insect Genomics and Proteomics” presents multiple perspectives of recognized experts from around the world in genomics, bioinformatics, molecular biology, biochemistry, physiology, and immunology, emphasizing fast-moving areas of current research on insects and other arthropods. Concise, accessible, topical reviews include body lice and white fly genome projects, aphid phenotypic plasticity, insect regulatory genomics, the complex tick sialome, protein expression systems, therapeutic potential of insect antimicrobial peptides, nanoparticle insecticides, and novel uses for recombinant and synthetic spider silks.