Radiochemical Synthesis

Author : Boris Ildusovich Kharisov
Publisher : CRC Press
ISBN 13 : 1466505230
Total Pages : 586 pages
Book Rating : 4.30/5 ( download)

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Download or read book Radiation Synthesis of Materials and Compounds written by Boris Ildusovich Kharisov and published by CRC Press. This book was released on 2016-04-19 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers and engineers working in nuclear laboratories, nuclear electric plants, and elsewhere in the radiochemical industries need a comprehensive handbook describing all possible radiation-chemistry interactions between irradiation and materials, the preparation of materials under distinct radiation types, the possibility of damage of material

Author : Peter J. H. Scott
Publisher :
ISBN 13 :
Total Pages : 343 pages
Book Rating : 4.11/5 ( download)

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Download or read book Radiochemical Synthesis written by Peter J. H. Scott and published by . This book was released on 2012 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Peter J. H. Scott
Publisher : John Wiley & Sons
ISBN 13 : 1118834003
Total Pages : 288 pages
Book Rating : 4.08/5 ( download)

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Download or read book Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production written by Peter J. H. Scott and published by John Wiley & Sons. This book was released on 2015-05-05 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes methods and procedures for preparing PETradiopharmaceuticals, and highlights new methods for conductingradiochemical reactions with carbon-11 (C11) and fluorine-18 (F18),which are two of the most commonly used radionuclides in positronemission tomography (PET) imaging. • Provides reliable methods forradiochemical syntheses and reactions, including all essentialinformation to duplicate the procedure • Eliminates the time-consuming process ofsearching journal articles and extracting pertinent details fromlengthy experimental sections or supporting information • Focuses on an emerging and important areafor pharmaceutical and medical applications • Encompasses technical, regulatory, andapplication aspects • Includes solid-phase radiochemistry,transition-metal catalyzed radiochemistry, microfluidics, clickchemistry, green radiochemistry and new strategies forradiopharmaceutical quality control

Author : Michael R. Kilbourn
Publisher : John Wiley & Sons
ISBN 13 : 1119500540
Total Pages : 768 pages
Book Rating : 4.44/5 ( download)

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Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Author : Rolf Voges
Publisher : John Wiley & Sons
ISBN 13 : 9780470743430
Total Pages : 682 pages
Book Rating : 4.33/5 ( download)

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Download or read book Preparation of Compounds Labeled with Tritium and Carbon-14 written by Rolf Voges and published by John Wiley & Sons. This book was released on 2009-03-12 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.

Author : Gregory Choppin
Publisher : Butterworth-Heinemann
ISBN 13 : 0750674636
Total Pages : 726 pages
Book Rating : 4.38/5 ( download)

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Download or read book Radiochemistry and Nuclear Chemistry written by Gregory Choppin and published by Butterworth-Heinemann. This book was released on 2002 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Origin of Nuclear Science; Nuclei, Isotopes and Isotope Separation; Nuclear Mass and Stability; Unstable Nuclei and Radioactive Decay; Radionuclides in Nature; Absorption of Nuclear Radiation; Radiation Effects on Matter; Detection and Measurement Techniques; Uses of Radioactive Tracers; Cosmic Radiation and Elementary Particles; Nuclear Structure; Energetics of Nuclear Reactions; Particle Accelerators; Mechanics and Models of Nuclear Reactions; Production of Radionuclides; The Transuranium Elements; Thermonuclear Reactions: the Beginning and the Future; Radiation Biology and Radiation Protection; Principles of Nuclear Power; Nuclear Power Reactors; Nuclear Fuel Cycle; Behavior of Radionuclides in the Environment; Appendices; Solvent Extraction Separations; Answers to Exercises; Isotope Chart; Periodic Table of the Elements; Quantities and Units; Fundamental Constants; Energy Conversion Factors; Element and Nuclide Index; Subject Index.

Author : Peter J. H. Scott
Publisher : John Wiley & Sons
ISBN 13 : 0470588950
Total Pages : 368 pages
Book Rating : 4.56/5 ( download)

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Download or read book Radiopharmaceuticals for Positron Emission Tomography, Volume 1 written by Peter J. H. Scott and published by John Wiley & Sons. This book was released on 2012-03-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate reference guide to the synthesis of radiopharmaceuticals The Radiochemical Syntheses series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory. Volume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience. Readers have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.

Author :
Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.63/5 ( download)

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Download or read book Radiochemical Analysis written by and published by . This book was released on 1964 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Yuji Kuge
Publisher : Springer
ISBN 13 : 4431558942
Total Pages : 326 pages
Book Rating : 4.41/5 ( download)

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Download or read book Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy written by Yuji Kuge and published by Springer. This book was released on 2016-04-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.

Author : H.Gerhard Vogel
Publisher : Springer Science & Business Media
ISBN 13 : 3540898905
Total Pages : 576 pages
Book Rating : 4.00/5 ( download)

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Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".