Neuronal Networks Of The Hippocampus

Author : Roger D. Traub
Publisher : Cambridge University Press
ISBN 13 : 0521364817
Total Pages : 306 pages
Book Rating : 4.12/5 ( download)

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Download or read book Neuronal Networks of the Hippocampus written by Roger D. Traub and published by Cambridge University Press. This book was released on 1991-05-31 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The questions of how a large population of neurons in the brain functions, how synchronized firing of neurons is achieved, and what factors regulate how many and which neurons fire under different conditions form the central theme of this book. Important neurological techniques for the physiological reconstruction of a large biological neural network are presented.

Author : Carl Faingold
Publisher : Academic Press
ISBN 13 : 0124158641
Total Pages : 537 pages
Book Rating : 4.41/5 ( download)

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Download or read book Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Author : Mark A. Gluck
Publisher : MIT Press
ISBN 13 : 9780262571524
Total Pages : 470 pages
Book Rating : 4.28/5 ( download)

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Download or read book Gateway to Memory written by Mark A. Gluck and published by MIT Press. This book was released on 2001 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for students and researchers who have a specific interest in learning and memory and want to understand how computational models can be integrated into experimental research on the hippocampus and learning. It emphasizes the function of brain structures as they give rise to behavior, rather than the molecular or neuronal details. It also emphasizes the process of modeling, rather than the mathematical details of the models themselves. The book is divided into two parts. The first part provides a tutorial introduction to topics in neuroscience, the psychology of learning and memory, and the theory of neural network models. The second part, the core of the book, reviews computational models of how the hippocampus cooperates with other brain structures -- including the entorhinal cortex, basal forebrain, cerebellum, and primary sensory and motor cortices -- to support learning and memory in both animals and humans. The book assumes no prior knowledge of computational modeling or mathematics. For those who wish to delve more deeply into the formal details of the models, there are optional "mathboxes" and appendices. The book also includes extensive references and suggestions for further readings.

Author : Ronald MacGregor
Publisher : Elsevier
ISBN 13 : 0323143849
Total Pages : 656 pages
Book Rating : 4.44/5 ( download)

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Download or read book Neural and Brain Modeling written by Ronald MacGregor and published by Elsevier. This book was released on 2012-12-02 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural and Brain Modeling reviews models used to study neural interactions. The book also discusses 54 computer programs that simulate the dynamics of neurons and neuronal networks to illustrate between unit and systemic levels of nervous system functions. The models of neural and brain operations are composed of three sections: models of generic mechanisms; models of specific neuronal systems; and models of generic operations, networks, and systems. The text discusses the computational problems related to galvanizing a neuronal population though an activity in the multifiber input system. The investigator can use a computer technique to simulate multiple interacting neuronal populations. For example, he can investigate the case of a single local region that contains two populations of neurons: namely, a parent population of excitatory cells, and a second set of inhibitory neurons. Computer simulation models predict the various dynamic activity occurring in the complicated structure and physiology of neuronal systems. Computer models can be used in "top-down" brain/mind research where the systemic, global, and emergent properties of nervous systems are generated. The book is recommended for behavioral scientists, psychiatrists, psychologists, computer programmers, students, and professors in human behavior.

Author : Vincent Torre
Publisher : Springer Science & Business Media
ISBN 13 : 3642589553
Total Pages : 245 pages
Book Rating : 4.53/5 ( download)

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Download or read book Neural Circuits and Networks written by Vincent Torre and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of parallel processing and of the mechanisms underlying neural networks in the brain is certainly one of the most challenging problems of contemporary science. During the last decades significant progress has been made by the combination of different techniques, which have elucidated properties at a cellular and molecular level. However, in order to make significant progress in this field, it is necessary to gather more direct experimental data on the parallel processing occurring in the nervous system. Indeed the nervous system overcomes the limitations of its elementary components by employing a massive degree of parallelism, through the extremely rich set of synaptic interconnections between neurons. This book gathers a selection of the contributions presented during the NATO ASI School "Neuronal Circuits and Networks" held at the Ettore Majorana Center in Erice, Sicily, from June 15 to 27, 1997. The purpose of the School was to present an overview of recent results on single cell properties, the dynamics of neuronal networks and modelling of the nervous system. The School and the present book propose an interdisciplinary approach of experimental and theoretical aspects of brain functions combining different techniques and methodologies.

Author : Vassilis Cutsuridis
Publisher : Springer Science & Business Media
ISBN 13 : 1441909966
Total Pages : 619 pages
Book Rating : 4.61/5 ( download)

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Download or read book Hippocampal Microcircuits written by Vassilis Cutsuridis and published by Springer Science & Business Media. This book was released on 2010-02-01 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rich in detail, Hippocampal Microcircuits: A Computational Modeler’s Resource Book provides succinct and focused reviews of experimental results. It is an unparalleled resource of data and methodology that will be invaluable to anyone wishing to develop computational models of the microcircuits of the hippocampus. The editors have divided the material into two thematic areas. Covering the subject’s experimental background, leading neuroscientists discuss the morphological, physiological and molecular characteristics as well as the connectivity and synaptic properties of the various cell types found in the hippocampus. Here, ensemble activity, related to behavior, on the part of morphologically identified neurons in anesthetized and freely moving animals, lead to insights into the functions of hippocampal areas. In the second section, on computational analysis, computational neuroscientists present models of hippocampal microcircuits at various levels of detail, including single-cell and network levels. A full chapter is devoted to the single-neuron and network simulation environments currently used by computational neuroscientists in developing their models. In addition to the above, the chapters also identify outstanding questions and areas in need of further clarification that will guide future research by computational neuroscientists.

Author : Michelangelo Colavita
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.12/5 ( download)

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Download or read book Dynamics of Hippocampal Networks Revealed by Voltage Sensitive Dye Imaging written by Michelangelo Colavita and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to better understand brain functioning we need to investigate all the structural domains present in it, from single cell to interconnected entire brain regions. However, while our knowledge in terms of single/few cells functioning is vast, very little is known about neuronal networks, which are interacting collections of neurons functionally related to the same task. Moreover, the balanced and concerted activity of excitatory and inhibitory networks plays a key role for proper cortical computations. However, while exist several tools to record excitatory networks activity, this is not the case for inhibitory networks. Voltage sensitive dye imaging (VSDI) is a technique that allows the recording of neuronal activity by mean of proportional emission of fluorescence according to changes in membrane potential. The advantage of using VSDI over other recording techniques using electrodes is that VSDI allows not invasive recording of neuronal activity from hundreds of sites at the same time. During my doctoral course I aimed at studying in detail excitatory and inhibitory neuronal networks in the CA1 area of mouse hippocampus with VSDI. To study excitatory networks more comprehensively, in collaboration with a team of mathematicians, we developed a mathematical algorithm that allowed measuring the velocity and the direction of spreading of the VSDI signal and it represents a new method to determine an optical flow. After successful validation of the algorithm with surrogate data to test its accuracy, we analysed two set of experiments in which network excitatory activity has been manipulated either by increasing Schaffer's collaterals stimulation intensity or by blocking GABAergic transmission with the GABAA receptor antagonist picrotoxin in order to increase the depolarization in the CA1 region of the hippocampus. The results of these manipulations significantly decreased signal velocity whereas picrotoxin application significantly modified the direction of spreading, making the depolarization-mediated VSDI signal less dispersed compared to control. Using VSDI I was able to fully characterize GABAA receptor-mediated hyperpolarizing signals in all the CA1 sublayers (field IPSPs), thus providing a new way of monitoring inhibitory events at network level. Moreover, I found that the activation of mGluR5 receptors induced an increase in a long-lasting manner of the VSDI-recorded field IPSPs, with duration and magnitude that relied on the specific CA1 sublayer considered. Overall, my work shows new methodologies and new findings that may represent a step forward in the quest for a better understanding of neuronal networks, both excitatory as well as inhibitory, which hopefully can contribute to reduce the gap of knowledge between single cell activity and behaviour.

Author : Reena Priti Murmu
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.18/5 ( download)

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Download or read book Refinement of Neuronal Networks in the Rodent Prefrontal Cortex and Hippocampus written by Reena Priti Murmu and published by . This book was released on 2007 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Karl Pribram
Publisher : Elsevier
ISBN 13 : 0323141501
Total Pages : 337 pages
Book Rating : 4.05/5 ( download)

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Download or read book Biology of Memory written by Karl Pribram and published by Elsevier. This book was released on 2012-12-02 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Memory investigates the biological basis of memory and covers topics ranging from short- and long-term post-perceptual memory to memory storage processes, memory microstructures, chemical transfer, and neuronal plasticity. The activity of neuronal networks in the thalamus of the monkey is also examined, along with integrative functions of the thalamocortical visual system of the cat. Comprised of 20 chapters, this book begins with an overview of the mechanisms that inhibit or interfere with short- and long-term memory, followed by a discussion on different retrieval mechanisms for short- and long-term memory. The reader is then introduced to the role of short- and long-term memory in the formation, retention, and utilization of associations, together with the link between memory and the medial temporal regions of the brain. Subsequent chapters focus on anatomical and chemical changes in the brain during primary learning; cellular models of learning and cellular mechanisms of plasticity in Aplysia; trace phenomena in single neurons of hippocampus and mammiliary bodies; and plasticity in single units in the mammalian brain. The book concludes with a description of Occam (Omnium-Gatherum Core Content Addressable Memory), a computer program for a content addressable memory in the central nervous system. This monograph will be useful to biologists, behavioral psychologists, neuropsychologists, neurophysiologists, biophysicists, and biochemists as well as computer scientists and mathematicians.

Author : Helmut L. Haas
Publisher : Springer Science & Business Media
ISBN 13 : 364273202X
Total Pages : 219 pages
Book Rating : 4.27/5 ( download)

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Download or read book Synaptic Plasticity in the Hippocampus written by Helmut L. Haas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.