Microbial And Phenotypic Definition Of Rats And Mice

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309172829
Total Pages : 113 pages
Book Rating : 4.20/5 ( download)

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Download or read book Microbial and Phenotypic Definition of Rats and Mice written by National Research Council and published by National Academies Press. This book was released on 1999-07-26 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309065917
Total Pages : 114 pages
Book Rating : 4.17/5 ( download)

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Download or read book Microbial and Phenotypic Definition of Rats and Mice written by National Research Council and published by National Academies Press. This book was released on 1999-08-26 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 9780309073899
Total Pages : 110 pages
Book Rating : 4.98/5 ( download)

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Download or read book Microbial and Phenotypic Definition of Rats and Mice written by National Research Council and published by National Academies Press. This book was released on 1999-07-26 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.

Author : Trenton R Schoeb
Publisher : Academic Press
ISBN 13 : 0128045833
Total Pages : 428 pages
Book Rating : 4.31/5 ( download)

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Download or read book Gnotobiotics written by Trenton R Schoeb and published by Academic Press. This book was released on 2017-08-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309171474
Total Pages : 166 pages
Book Rating : 4.72/5 ( download)

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Download or read book Microbial Status and Genetic Evaluation of Mice and Rats written by National Research Council and published by National Academies Press. This book was released on 2000-10-30 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: US/Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US/Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes. In addition to these publications, the meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats. In cooperation with the Comparative Medicine section of NCRR/NIH, the ILAR Council and staff are pleased to become the host for this important annual meeting and look forward to participating in future meetings. The support and sponsorship of NCRR (P40 RR 11611) in the United States and the Central Institute for Experimental Animals in Japan are gratefully acknowledged. Bringing together the leading scientists in the field of laboratory animal care has resulted in increased understanding of American and Japanese approaches to laboratory animal science and should continue to strengthen efforts to harmonize approaches aimed at resolving common challenges in the use of animal models for biomedical research and testing. This effort to improve understanding and cooperation between Japan and the United States should also be useful in developing similar interaction with other regions of the world including Europe, Australia, and Southeast Asia.

Author : Edward C. Jr. Melby
Publisher : Elsevier
ISBN 13 : 0323157033
Total Pages : 301 pages
Book Rating : 4.32/5 ( download)

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Download or read book The Importance of laboratory animal genetics Health, and the Environment in Biomedical Research written by Edward C. Jr. Melby and published by Elsevier. This book was released on 2012-12-02 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Importance of Laboratory Animal Genetics, Health, and the Environment in Biomedical Research documents the proceedings of the Fifth Charles River International Symposium on Laboratory Animals, in Heidelberg, Federal Republic of Germany, March 14-16, 1983. These papers examine how the health and genetic monitoring of laboratory animals, coupled with environmental influences, affect the investigations of oncologists, toxicologists, or pharmacologists. The book is organized into four parts. Part I focuses on the health monitoring of laboratory animals for biomedical research. It includes studies on the effects of health and health monitoring in toxicology studies, oncology studies, and pharmacologic studies. Part II deals with the genetic monitoring of laboratory animals. It examines the causes of genetic alternation in laboratory animals and ways to prevent them. Part III considers the environmental monitoring that is necessary for research on laboratory animals. Part IV on new research frontiers includes studies on the production of monoclonal antibodies for the experimental and therapeutic modulation of laboratory animals, and the quality control aspects of animal experimentation.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.57/5 ( download)

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Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Author : Maclyn McCarty
Publisher : W. W. Norton & Company
ISBN 13 : 9780393304503
Total Pages : 258 pages
Book Rating : 4.07/5 ( download)

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Download or read book The Transforming Principle written by Maclyn McCarty and published by W. W. Norton & Company. This book was released on 1986 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forty years ago, three medical researchers--Oswald Avery, Colin MacLeod, and Maclyn McCarty--made the discovery that DNA is the genetic material. With this finding was born the modern era of molecular biology and genetics.

Author : Peggy J. Danneman
Publisher : CRC Press
ISBN 13 : 143985422X
Total Pages : 247 pages
Book Rating : 4.28/5 ( download)

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Download or read book The Laboratory Mouse written by Peggy J. Danneman and published by CRC Press. This book was released on 2012-09-25 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a

Author : Beverley Isherwood
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160799
Total Pages : 273 pages
Book Rating : 4.90/5 ( download)

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Download or read book Phenotypic Drug Discovery written by Beverley Isherwood and published by Royal Society of Chemistry. This book was released on 2020-12-09 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of new medical entities. How many marketed drugs are derived from phenotypic screens? From the most recent examples, what were the factors enabling target identification and validation? This book answers these questions by elaborating on fundamental capabilities required for phenotypic drug discovery and using case studies to illustrate approaches and key success factors. Written and edited by experienced practitioners from both industry and academia, this publication will equip researchers with a thought-provoking guide to the application and future development of contemporary phenotypic drug discovery for clinical success.