Introduction To Cancer Metastasis

Author : Aamir Ahmad
Publisher : Academic Press
ISBN 13 : 0128040335
Total Pages : 416 pages
Book Rating : 4.31/5 ( download)

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Download or read book Introduction to Cancer Metastasis written by Aamir Ahmad and published by Academic Press. This book was released on 2016-11-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives. Includes basic biology and translational approaches to organ-specific cancer sites Provides readers with information on emerging therapeutic targets for cancer metastasis Contains contributions from leading researchers around the globe

Author : Venkateshwar Keshamouni
Publisher : Springer Science & Business Media
ISBN 13 : 1441907726
Total Pages : 409 pages
Book Rating : 4.21/5 ( download)

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Download or read book Lung Cancer Metastasis written by Venkateshwar Keshamouni and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.

Author : Momna Hejmadi
Publisher : Bookboon
ISBN 13 : 8776814785
Total Pages : 46 pages
Book Rating : 4.86/5 ( download)

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Download or read book Introduction to Cancer Biology written by Momna Hejmadi and published by Bookboon. This book was released on 2014* with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Introduction to Cancer Biology is a short primer on how cancers develop and grow. The aim of this book is to provide a gentle exploration of the fundamental concepts in a easy-to-understand format, using examples and key figures for illustration. It is written in a style to help the reader understand the six basic principles that inform our current understanding of cancer, at the molecular, cellular and physiological level. The text can be used either as a first step towards a deeper understanding of the mechanisms of cancer progression or it can be used as a quick revision guide. It would be suitable for anyone, with or without a background in biology."--Website.

Author : Yasemin Basbinar
Publisher : BoD – Books on Demand
ISBN 13 : 1789846323
Total Pages : 154 pages
Book Rating : 4.24/5 ( download)

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Download or read book Cancer Metastasis written by Yasemin Basbinar and published by BoD – Books on Demand. This book was released on 2018-12-05 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis.

Author : Anastasia Malek
Publisher : Springer Science & Business Media
ISBN 13 : 940077835X
Total Pages : 210 pages
Book Rating : 4.51/5 ( download)

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Download or read book Experimental Metastasis: Modeling and Analysis written by Anastasia Malek and published by Springer Science & Business Media. This book was released on 2013-12-02 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic cancer dissemination and metastases development. The book is structured in according with various metastatic pathways reflecting molecular specificity of metastatic process as well as anatomical specificity of aria of dissemination. Each chapter is introduced by short discussion of clinical aspects of certain metastatic pathway. Especial attention is paid for methods of visualization, quantification and analysis of the modeled metastases. Additional chapter is devoted to methods of mathematic modeling of tumor spread. The data presented in the book may be helpful for cancer researchers and oncologists.

Author : J.M. Debois
Publisher : Springer Science & Business Media
ISBN 13 : 0306476789
Total Pages : 757 pages
Book Rating : 4.85/5 ( download)

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Download or read book TxNxM1 written by J.M. Debois and published by Springer Science & Business Media. This book was released on 2006-05-08 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although distant metastases are the most dreaded situation in the evolution of cancer of every organ, the medical literature has surprisingly given little attention to the anatomical relationship between the primary tumor and metastasic sites. Only risk factors, treatment possibilities, and survival results are extensively examined. Stimulated by the occurrence in his practice of some puzzling and unexpected metastases, the author reviewed more than 12,000 references. He looked for anatomical relationships highlighting the relation between the location of the primary tumors and the particular patterns of metastasis observed. It would seem that the `pathways and flows' are apparently a more decisive factor in the implantation of the metastases than the `seed and soil' properties of the cancer cells and the metastatic site. Aided by his colleague Dr. T. Geukens, M.D., the author includes original anatomical drawings, illustrating the sometimes unexpected pathways the cancer cells follow in order to reach the organs where they will become lodged and give rise to metastatic tumors. The subject has apparently not been exhausted in the literature and several ideas are given for further research.

Author : Beata Ujvari
Publisher : Academic Press
ISBN 13 : 0128043806
Total Pages : 290 pages
Book Rating : 4.06/5 ( download)

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Download or read book Ecology and Evolution of Cancer written by Beata Ujvari and published by Academic Press. This book was released on 2017-02-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies

Author : Ammad Ahmad Farooqi
Publisher : Academic Press
ISBN 13 : 0128217901
Total Pages : 342 pages
Book Rating : 4.00/5 ( download)

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Download or read book Unraveling the Complexities of Metastasis written by Ammad Ahmad Farooqi and published by Academic Press. This book was released on 2022-05-14 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis. Explains the mechanism of metastasis from basic to advanced level through easy and comprehensive chapters written by internationally distinguished researchers Provides simplified version of important process of metastasis for the readers to comprehend the latest advancements made in the field Presents colorful diagrams to make different aspects of scientifically difficult topics easier for young researchers and newcomers in the field of cancer metastasis

Author : Gajanan V. Sherbet
Publisher : Academic Press
ISBN 13 : 9780080542485
Total Pages : 338 pages
Book Rating : 4.84/5 ( download)

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Download or read book The Genetics of Cancer written by Gajanan V. Sherbet and published by Academic Press. This book was released on 1997-06-22 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology. Clonal evolution of the metastasis phenotype Cell Cycle regulation Apoptosis in tumour growth and metastasis Angiogenesis in cancer Cell surface glycoproteins and their receptors Proteinases and their inhibitors in cancer invasion Oncogenes and cancer metastasis Developmental genes Tumour suppressor genes Metastasis suppressor genes Dominant metastasis-associated genes

Author : Kamal Dua
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 572 pages
Book Rating : 4.99/5 ( download)

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Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems