Innovative Drug Development For Headache Disorders

Author : Jes Olesen
Publisher : Oxford University Press
ISBN 13 : 0199552762
Total Pages : 240 pages
Book Rating : 4.64/5 ( download)

DOWNLOAD NOW!

Download or read book Innovative Drug Development for Headache Disorders written by Jes Olesen and published by Oxford University Press. This book was released on 2008-08-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This latest volume of the Frontiers in Headache Research series summarizes the several promising new avenues for the development of future drugs for the treatment of migraine.

Author : Hans-Christoph Diener
Publisher : Springer Science & Business Media
ISBN 13 : 3642733271
Total Pages : 174 pages
Book Rating : 4.77/5 ( download)

DOWNLOAD NOW!

Download or read book Drug-Induced Headache written by Hans-Christoph Diener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Author : Zoran M. Pavlovic
Publisher : Springer Nature
ISBN 13 : 303087480X
Total Pages : 623 pages
Book Rating : 4.03/5 ( download)

DOWNLOAD NOW!

Download or read book Glutamate and Neuropsychiatric Disorders written by Zoran M. Pavlovic and published by Springer Nature. This book was released on 2022-04-10 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.

Author : Jes Olesen
Publisher : Oxford University Press
ISBN 13 : 0199584680
Total Pages : 198 pages
Book Rating : 4.80/5 ( download)

DOWNLOAD NOW!

Download or read book Headache Care, Research and Education Worldwide written by Jes Olesen and published by Oxford University Press. This book was released on 2010-05-27 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings the theme of a global campaign to the forefront. Researchers, scientists, and respected clinicians from around the world discuss aspects of access to care, individual and societal burden.

Author : Jeffrey Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.45/5 ( download)

DOWNLOAD NOW!

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : Elizabeth Loder
Publisher : PMPH-USA
ISBN 13 : 9781550091809
Total Pages : 212 pages
Book Rating : 4.08/5 ( download)

DOWNLOAD NOW!

Download or read book Migraine in Women written by Elizabeth Loder and published by PMPH-USA. This book was released on 2004 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifteen specialists serve as chapter authors, covering sex hormones and genetics, as well as the social, cultural, psychiatric, and psychological factors that contribute to headache disorders. Their approach is evidence-based, but where there are gaps in research, the authors provide advice based on expert consensus and clinical experience. Each chapter opens with a case report that synthesizes the chapter's treatment recommendations, as well as key points listing the chapter's contents. The main body of the chapter features an introductory overview, a closing summary, tables, and an extensive list of suggestive reading.

Author : Katherine Foxhall
Publisher : Johns Hopkins University Press
ISBN 13 : 1421429489
Total Pages : 293 pages
Book Rating : 4.89/5 ( download)

DOWNLOAD NOW!

Download or read book Migraine written by Katherine Foxhall and published by Johns Hopkins University Press. This book was released on 2019-06-18 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deeply researched and beautifully written, this fascinating and accessible study of one of our most common, disabling—and yet often dismissed—disorders will appeal to physicians, historians, scholars in medical humanities, and people living with migraine alike.

Author : Dimos D. Mitsikostas
Publisher : Springer
ISBN 13 : 3319199110
Total Pages : 253 pages
Book Rating : 4.15/5 ( download)

DOWNLOAD NOW!

Download or read book Pharmacological Management of Headaches written by Dimos D. Mitsikostas and published by Springer. This book was released on 2015-08-26 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, headache experts summarize all the currently available therapies for primary headaches and most importantly, describe the ‘tricks’ that can ensure the success of headache pharmacotherapy. Prevention and acute treatment of migraine and cluster headache receive particular attention and individual chapters are devoted to the treatment of primary headaches in special groups, i.e. children, pregnant women and the elderly. Further chapters focus on selected secondary headache disorders and cranial neuralgias for which pharmacotherapy is available. The book is designed to meet the daily practice needs of general physicians, general neurologists, neurologists in training and medical students. Headache remains a leading reason for people to seek medical consultation, and migraine and other primary headache disorders are classified by the WHO as among the most disabling medical conditions in the general population, often affecting individuals during their most productive years. Unfortunately, under treatment and mismanagement are the fate of many headache patients and this book provides a sound basis for optimizing treatment.

Author : Paul R. Daugherty
Publisher : Harvard Business Press
ISBN 13 : 1647827213
Total Pages : 177 pages
Book Rating : 4.12/5 ( download)

DOWNLOAD NOW!

Download or read book Human + Machine, Updated and Expanded written by Paul R. Daugherty and published by Harvard Business Press. This book was released on 2024-09-10 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: AI—including generative AI—is radically transforming business. Are you ready? Accenture technology leaders Paul Daugherty and Jim Wilson provide crucial insights and advice to help you meet the challenge. Look around you. Artificial intelligence is no longer just a futuristic notion. It's here right now—in software that senses what we need, supply chains that "think" in real time, and now generative AI that is radically reshaping work and productivity. Twenty-first-century pioneer companies are already using AI to innovate and grow fast. The bottom line is this: Businesses that understand how to harness AI can surge ahead. Those that neglect it will fall behind. Which side are you on? In this updated and expanded edition of Human + Machine—including a new chapter on gen AI—Accenture technology leaders Paul Daugherty and Jim Wilson show that the essence of the AI paradigm shift is the transformation of all business processes within an organization, whether related to breakthrough innovation, everyday customer service, or personal productivity habits. As humans and smart machines collaborate ever more closely, work processes become more fluid and adaptive, enabling companies to change them on the fly—or completely reimagine them. Based on the authors' experience and research with fifteen hundred organizations, the book reveals how companies are using the new rules of AI to leap ahead on innovation and profitability and what you can do to achieve similar results. It describes six entirely new types of hybrid human + machine roles that every company must develop, and it includes a "leader's guide" with the five crucial principles required to become an AI-fueled business. Human + Machine provides the missing and much-needed management playbook for success in the new age of AI.

Author : Seymour Diamond
Publisher : Academic Press
ISBN 13 : 0128011629
Total Pages : 334 pages
Book Rating : 4.21/5 ( download)

DOWNLOAD NOW!

Download or read book Headache and Migraine Biology and Management written by Seymour Diamond and published by Academic Press. This book was released on 2015-03-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field. A practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs Features chapters from leading physicians and researchers in headache medicine Full-color text that includes both an overview of multiple disciplines and discusses the measures that can be used to treat headaches