Flow Cytometry Of Hematological Malignancies

Author : Claudio Ortolani
Publisher : John Wiley & Sons
ISBN 13 : 111961127X
Total Pages : 464 pages
Book Rating : 4.71/5 ( download)

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Download or read book Flow Cytometry of Hematological Malignancies written by Claudio Ortolani and published by John Wiley & Sons. This book was released on 2021-04-19 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow, and lymph nodes. However, in the fast-moving and expanding field of clinical hematology, in can be challenging to remain up to speed with the latest biological research and technological innovations. Flow Cytometry of Hematological Malignancies has been designed to provide all those working in hematological oncology with a practical, cutting-edge handbook, featuring clear and fully illustrated guidance on all aspects of cytometry’s role in diagnosis and analysis. This essential second edition includes: Explorations of more than 70 antigens Full-color illustrations throughout New descriptions of recently discovered markers WHO classifications of hematological neoplastic diseases Helpful tips for result interpretation and analysis Featuring all this and more, Flow Cytometry of Hematological Malignancies, Second Edition, is an invaluable resource for both trainee and experienced hematologists, hematopathologists, oncologists, and pathologists, as well as medical students and diagnostic lab technicians.

Author : Anna Porwit
Publisher : Cambridge University Press
ISBN 13 : 1108548830
Total Pages : 248 pages
Book Rating : 4.30/5 ( download)

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Download or read book Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies written by Anna Porwit and published by Cambridge University Press. This book was released on 2018-01-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.

Author : Tsieh Sun
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451180640
Total Pages : 449 pages
Book Rating : 4.40/5 ( download)

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Download or read book Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms written by Tsieh Sun and published by Lippincott Williams & Wilkins. This book was released on 2012-01-19 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.

Author : Mike Leach
Publisher : John Wiley & Sons
ISBN 13 : 9780470671207
Total Pages : 0 pages
Book Rating : 4.03/5 ( download)

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Download or read book Practical Flow Cytometry in Haematology Diagnosis written by Mike Leach and published by John Wiley & Sons. This book was released on 2013-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditionsCarefully chosen real-life cases in each chapter, complemented by high quality morphological images Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide.

Author : Ortolani
Publisher : Wiley-Blackwell
ISBN 13 : 9781394245147
Total Pages : 0 pages
Book Rating : 4.49/5 ( download)

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Download or read book Flow Cytometry of Hematological Malignancies, 3rd Edition written by Ortolani and published by Wiley-Blackwell. This book was released on 2026-09-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Doyen T. Nguyen
Publisher : Springer Science & Business Media
ISBN 13 : 1592593542
Total Pages : 231 pages
Book Rating : 4.45/5 ( download)

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Download or read book Flow Cytometry in Hematopathology written by Doyen T. Nguyen and published by Springer Science & Business Media. This book was released on 2002-11-26 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow cytometry immunophenotyping of hematopoietic disorders is a complex and demanding exercise that requires a good understanding of cell lineages, developmental pathways, and physiological changes, as well as broad experience in hematopathology. The process includes several interrelated stages, from the initial medical decision regarding which hematologic c- dition is appropriate for FCM assay, to the final step of diagnosis whereby the FCM data is correlated with other relevant clinical and laboratory information. The actual FCM testing involves three major steps: pre-analytical (specimen processing, antibody staining), analytical (acquiring data on the flow cytometer) and post-analytical (data analysis and interpretation). The literature, including the latest FCM textbooks, provides ample information on the te- nical principles of FCM such as instrumentation, reagents and laboratory methods, as well as quality control and quality assurance. Similarly, correlations of morphologic findings and p- notypic profiles have been well covered in many publications. In contrast, much less attention has been given to the other equally important aspects of FCM immunophenotyping, especially data analysis. The latter is a crucial step by which a phenotypic profile is established. To bridge this gap in the literature, the focus of this book is more on FCM data analysis than laboratory methods and technical details. For the reader to become familiar with our data analysis strategy, an overview of our approach to the pre-analytical and analytical steps is also presented, with an emphasis on the pre-analytical aspects, which have been rarely touched upon in the literature.

Author : Mike Leach
Publisher : John Wiley & Sons
ISBN 13 : 1118746899
Total Pages : 415 pages
Book Rating : 4.99/5 ( download)

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Download or read book Practical Flow Cytometry in Haematology written by Mike Leach and published by John Wiley & Sons. This book was released on 2015-06-01 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: Provides a practical, example-based resource for flow cytometry Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care Includes both malignant and benign conditions Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.

Author : Tsieh Sun
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781784009
Total Pages : 362 pages
Book Rating : 4.0X/5 ( download)

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Download or read book Flow Cytometry and Immunohistochemistry for Hematologic Neoplasms written by Tsieh Sun and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a detailed guide to the use of flow cytometry, immunohistochemistry, and molecular genetic techniques for diagnosis of hematologic neoplasms. Dr. Sun explains the principles of these techniques and demonstrates their utility in 39 clinical cases covering all important entities. Each case represents a comprehensive diagnostic approach including a clinical history and flow cytometric, immunohistochemical, and molecular genetic findings. Abundant full-color illustrations show histologic sections, immunohistochemical stains, bone marrow, peripheral blood, and body fluid smears, and each case includes a complete set of flow cytometric histograms. Over 100 tables compare and differentiate the diagnostic features of similar diseases. An image bank will be available on a companion Website.

Author : Wojciech Gorczyca
Publisher : CRC Press
ISBN 13 : 1841847445
Total Pages : 350 pages
Book Rating : 4.43/5 ( download)

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Download or read book Flow Cytometry in Neoplastic Hematology written by Wojciech Gorczyca and published by CRC Press. This book was released on 2010-02-25 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly illustrated, practical guide contains comprehensive coverage of all the important factors for clinical diagnosis with flow cytometry. It explains the general parameters and correlation with color histomorphological findings throughout, taking a systematic approach from basic cases to complicated problem areas. Hematopathologists and neoplastic hematologists will find this book an important resource for keeping up to date with developments in clinical practice. This second edition includes a chapter on antigen expression during myeloid and lymphoid differentiation.

Author : Barbara Buldini
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.32/5 ( download)

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Download or read book Flow Cytometry Application in Hematological Malignancies of Childhood written by Barbara Buldini and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: