Dna Damage Dna Repair And Disease Volume 2

Author : Miral Dizdaroglu
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162562
Total Pages : 509 pages
Book Rating : 4.65/5 ( download)

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Download or read book DNA Damage, DNA Repair and Disease written by Miral Dizdaroglu and published by Royal Society of Chemistry. This book was released on 2020-11-11 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

Author : Jac A. Nickoloff
Publisher : Springer Science & Business Media
ISBN 13 : 1592594557
Total Pages : 1050 pages
Book Rating : 4.59/5 ( download)

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Download or read book DNA Damage and Repair written by Jac A. Nickoloff and published by Springer Science & Business Media. This book was released on 1998-08-12 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.

Author : Miral Dizdaroglu
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160861
Total Pages : 429 pages
Book Rating : 4.68/5 ( download)

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Download or read book DNA Damage, DNA Repair and Disease written by Miral Dizdaroglu and published by Royal Society of Chemistry. This book was released on 2020-11-11 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

Author : Jac A. Nickoloff
Publisher : Springer Science & Business Media
ISBN 13 : 1592590950
Total Pages : 417 pages
Book Rating : 4.57/5 ( download)

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Download or read book DNA Damage and Repair written by Jac A. Nickoloff and published by Springer Science & Business Media. This book was released on 2001-03-13 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, and explains the important functional relationships among different DNA repair pathways and the relationship between DNA repair pathways, cancer etiology, and cancer therapies.

Author : Jac A. Nickoloff
Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.50/5 ( download)

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Download or read book DNA Damage and Repair written by Jac A. Nickoloff and published by Springer Science & Business Media. This book was released on 1998-01-21 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the tradition of presenting information on DNA damage and repair, this 3rd volume provides the latest reviews by leading researchers. They illuminate key aspects of DNA repair in mammalian systems and its relationship to human disease.

Author : Errol C. Friedberg
Publisher : American Society for Microbiology Press
ISBN 13 : 1555813194
Total Pages : 2587 pages
Book Rating : 4.92/5 ( download)

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Download or read book DNA Repair and Mutagenesis written by Errol C. Friedberg and published by American Society for Microbiology Press. This book was released on 2005-11-22 with total page 2587 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Author :
Publisher :
ISBN 13 : 9780929600871
Total Pages : 1118 pages
Book Rating : 4.78/5 ( download)

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Download or read book DNA Repair and Mutagenesis written by and published by . This book was released on 2006 with total page 1118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely reorganized, the new edition presents a significant overhaul of the existing chapters and introduces important new material, reflective of the major changes and developments that have occurred in the field over the last decade. As with the first edition, this new volume presents the field within a strong historical framework and all aspects of biological responses to DNA damage are detailed. The book consists of 30 chapters divided into five main parts, covering: sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage. Basic principles are appropriately stressed; however, the book focuses on the significant progress to date and future research directions.

Author : Michael G. Simic
Publisher : Springer Science & Business Media
ISBN 13 : 1461594626
Total Pages : 567 pages
Book Rating : 4.28/5 ( download)

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Download or read book Mechanisms of DNA Damage and Repair written by Michael G. Simic and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.

Author : Roger J. A. Grand
Publisher : Garland Science
ISBN 13 : 0429876548
Total Pages : 368 pages
Book Rating : 4.47/5 ( download)

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Download or read book DNA Repair and Replication written by Roger J. A. Grand and published by Garland Science. This book was released on 2018-09-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways. Key Selling Features: Chapters written by leading researchers Includes description of replication processes, causes of damage, and methods of repair

Author : Shamim Ahmad
Publisher : Springer Science & Business Media
ISBN 13 : 1441964487
Total Pages : 282 pages
Book Rating : 4.89/5 ( download)

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Download or read book Diseases of DNA Repair written by Shamim Ahmad and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer. The purpose of this book is to present an updated detailed account of some important additional diseases of DNA repair. It has not been possible to cover all the DNA repair deficient diseases in this volume, hence diseases such as Bloom’s syndrome, Werner’s syndrome, Nijmegen breakage syndrome, ataxia telangiectasia‐like disorder, RA D 50 deficiency, RIDDLE syndrome and others will be presented in a forthcoming volume.