Clinical Challenges

Author : William Clarke
Publisher : Elsevier
ISBN 13 : 9780128020258
Total Pages : 0 pages
Book Rating : 4.53/5 ( download)

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Download or read book Clinical Challenges in Therapeutic Drug Monitoring written by William Clarke and published by Elsevier. This book was released on 2016-05-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.

Author : Veronica Bishop
Publisher : Bloomsbury Publishing
ISBN 13 : 1403937370
Total Pages : 208 pages
Book Rating : 4.77/5 ( download)

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Download or read book Challenges in Clinical Practice written by Veronica Bishop and published by Bloomsbury Publishing. This book was released on 2017-03-14 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Challenges in Clinical Practice aims to support nurses and other health care workers in taking the health care agenda forward. With the constant bombardment of changes in policy initiatives, and the accompanying challenges which face nurses and other health care professionals this book will be a welcome asset to a strained labour market. It addresses the key issues and critical challenges facing the health care services today such as clinical governance, managing change, supervision in practice and research based practice. Nurses represent the fastest growing users of IT and as such the importance and simplicity of IT in supporting current challenges is also explored. The demystification of IT is brilliantly executed here and useful samplers are provided. Central to all changes are the needs of clients and patients, and partnerships in care - the power bases of service provision. The complex realities of this are probed, sometimes disconcertingly, within this important text. Written and edited by key professionals in the field, this text is an invaluable resource for pre- and post-registration students, those in middle and senior management positions and all teaching staff within the health sector. It is essential reading for anyone who wants to accept the challenge of providing the best in health care services.

Author : David R Ramsdale
Publisher : World Scientific Publishing Company
ISBN 13 : 9814365289
Total Pages : 256 pages
Book Rating : 4.84/5 ( download)

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Download or read book 100 Diagnostic Challenges in Clinical Medicine written by David R Ramsdale and published by World Scientific Publishing Company. This book was released on 2009-03-04 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: 100 Diagnostic Challenges in Clinical Medicine is composed of one hundred well-illustrated clinical scenarios and their appropriate investigations. A wide variety of specialties are covered including cardiology, neurology, dermatology, endocrinology, tropical medicine, haematology, metabolic medicine, radiology, ophthalmology, venereology, and infectious diseases. Presenting the relevant investigations corresponding to each case in an interesting and easy-to-read Q&A format concerning diagnosis and management, this book serves as an ideal, and hopefully enjoyable, study aid for medical students and junior doctors who are preparing for clinical examinations in medicine. By solving the problems posed by these challenging clinical cases, the reader will gain additional practice in diagnosis and treatment strategies.

Author : JUDY. PICONE LUMBY (DEBBIE.)
Publisher : Routledge
ISBN 13 : 9780367717698
Total Pages : 240 pages
Book Rating : 4.97/5 ( download)

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Download or read book Clinical Challenges written by JUDY. PICONE LUMBY (DEBBIE.) and published by Routledge. This book was released on 2021-03-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nurses work across the health care system in a great variety of roles. From patient care to administration, nurses see where the pressures are, and how well we are managing to look after some of the most vulnerable people in our society. Clinical Challenges explores contemporary issues central to nurses' work. Part I explores clinical concerns such as pain and wound management, the role of the nurse practitioner, and the effects of extending life. For many years the health sector has been coping with cutbacks in government funding, and Part II examines how this impacts on the way we handle social illnesses such as suicide and drug dependence, as well as the needs of our growing ageing population. Part III looks at management issues affecting nurses including the growing use of business strategies and rhetoric in the health care system, and the introduction of information systems and of more flexible ways of working. Written by nurses working in a variety of professional roles in the system and critiqued by experts in the field, Clinical Challenges offers valuable insights for nurses at every level, including students.

Author : Mauricio Tohen
Publisher : Academic Press
ISBN 13 : 0124051766
Total Pages : 192 pages
Book Rating : 4.68/5 ( download)

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Download or read book Clinical Trial Design Challenges in Mood Disorders written by Mauricio Tohen and published by Academic Press. This book was released on 2015-01-24 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. Summarizes common trial design problems and their solutions Encompasses funding, subject selection, regulatory issues and more Identifies best practices for definitive and generalizable results Includes traditional trial designs and novel analytic techniques Represents academia, industry, regulatory agencies, and advocacy groups

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309262011
Total Pages : 159 pages
Book Rating : 4.19/5 ( download)

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Download or read book The Role of Telehealth in an Evolving Health Care Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2012-12-20 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996, the Institute of Medicine (IOM) released its report Telemedicine: A Guide to Assessing Telecommunications for Health Care. In that report, the IOM Committee on Evaluating Clinical Applications of Telemedicine found telemedicine is similar in most respects to other technologies for which better evidence of effectiveness is also being demanded. Telemedicine, however, has some special characteristics-shared with information technologies generally-that warrant particular notice from evaluators and decision makers. Since that time, attention to telehealth has continued to grow in both the public and private sectors. Peer-reviewed journals and professional societies are devoted to telehealth, the federal government provides grant funding to promote the use of telehealth, and the private technology industry continues to develop new applications for telehealth. However, barriers remain to the use of telehealth modalities, including issues related to reimbursement, licensure, workforce, and costs. Also, some areas of telehealth have developed a stronger evidence base than others. The Health Resources and Service Administration (HRSA) sponsored the IOM in holding a workshop in Washington, DC, on August 8-9 2012, to examine how the use of telehealth technology can fit into the U.S. health care system. HRSA asked the IOM to focus on the potential for telehealth to serve geographically isolated individuals and extend the reach of scarce resources while also emphasizing the quality and value in the delivery of health care services. This workshop summary discusses the evolution of telehealth since 1996, including the increasing role of the private sector, policies that have promoted or delayed the use of telehealth, and consumer acceptance of telehealth. The Role of Telehealth in an Evolving Health Care Environment: Workshop Summary discusses the current evidence base for telehealth, including available data and gaps in data; discuss how technological developments, including mobile telehealth, electronic intensive care units, remote monitoring, social networking, and wearable devices, in conjunction with the push for electronic health records, is changing the delivery of health care in rural and urban environments. This report also summarizes actions that the U.S. Department of Health and Human Services (HHS) can undertake to further the use of telehealth to improve health care outcomes while controlling costs in the current health care environment.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.44/5 ( download)

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Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Author : Lindsey Biel
Publisher : W. W. Norton & Company
ISBN 13 : 0393709086
Total Pages : 296 pages
Book Rating : 4.87/5 ( download)

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Download or read book Sensory Processing Challenges: Effective Clinical Work with Kids & Teens written by Lindsey Biel and published by W. W. Norton & Company. This book was released on 2014-02-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Equipping clinicians with “sensory smarts” to treat their child clients. Many children, teens, and even adults experience sensory processing challenges including out-of-proportion reactions to certain sensory experiences that most of us find commonplace. These challenges can range from mild to severe—from difficulty tolerating fluorescent lights and discomfort with certain clothing textures, to fight-or-flight reactions to unexpected or loud noises such as sirens or automatic hand dryers, or such strong oral sensitivities that the individual can tolerate eating just a few foods. They may struggle with one or more “sensory channels," or, more often, be quickly overwhelmed by the demand to process multisensory input (especially in busy environments with competing sights, sounds, and smells), leading to poor self-regulation, acting out, and tuning out. Sensory challenges, sometimes referred to as Sensory Processing Disorder when they interfere with daily function, are frequently seen in tandem with autism, anxiety, attention disorders, oppositional defiant disorder, and other diagnoses. This book equips clinicians with all the information they need to know to recognize and understand sensory sensitivities; connect the dots between behavior and underlying sensory processing problems; when to refer and collaborate with sensory processing professionals; and essential “sensory smart” strategies that can help clients feel and function at their best at home, in school, and in the community.

Author : Patrick Coppens
Publisher : Jones & Bartlett Learning
ISBN 13 : 1284042715
Total Pages : 494 pages
Book Rating : 4.19/5 ( download)

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Download or read book Aphasia Rehabilitation written by Patrick Coppens and published by Jones & Bartlett Learning. This book was released on 2017-01-05 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aphasia Rehabilitation: Challenging Clinical Issues focuses on specific aphasia symptoms and clinical issues that present challenges for rehabilitation professionals. These topics are typically not addressed as separate topics, even in clinical texts. This heavily clinical text will also include thorough discussions of theoretical underpinnings. For chapters that focus on specific clinical challenges, practical suggestions to facilitate clinical application and maximize clinical usefulness. This resource integrates theoretical and practical information to aid a clinician in planning treatment for individuals with aphasia.

Author : Lucia Siegel Sommers
Publisher : Springer Science & Business Media
ISBN 13 : 1461468124
Total Pages : 311 pages
Book Rating : 4.27/5 ( download)

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Download or read book Clinical Uncertainty in Primary Care written by Lucia Siegel Sommers and published by Springer Science & Business Media. This book was released on 2013-07-05 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Power of Colleagues What happens when primary care clinicians meet together on set aside time in their practice settings to talk about their own patients? .....Complimenting quality metrics or performance measures through discussing the actual stories of individual patients and their clinician-patient relationships In these settings, how can clinicians pool their collective experience and apply that to ‘the evidence’ for an individual patient? .....Especially for patients who do not fit the standard protocols and have vague and worrisome symptoms, poor response to treatment, unpredictable disease courses, and/or compromised abilities for shared decision making What follows when discussion about individual patients reveals system-wide service gaps and coordination limitations? .....Particularly for patients with complex clinical problems that fall outside performance monitors and quality screens How can collaborative engagement of case-based uncertainties with one’s colleagues help combat the loneliness and helplessness that PCPs can experience, no matter what model or setting in which they practice? .....And where they are expected to practice coordinated, evidence-based, EMR-directed care These questions inspired Lucia Sommers and John Launer and their international contributors to explore the power of colleagues in “Clinical Uncertainty in Primary Care: The Challenge of Collaborative Engagement” and offer antidotes to sub-optimal care that can result when clinicians go it alone. From the Foreword: “Lucia Sommers and John Launer, with the accompanying input of their contributing authors, have done a deeply insightful and close-to-exhaustive job of defining clinical uncertainty. They identify its origins, components and subtypes; demonstrate the ways in which and the extent to which it is intrinsic to medicine...and they present a cogent case for its special relationship to primary care practice...‘Clinical Uncertainty in Primary Care’ not only presents a model of collegial collaboration and support, it also implicitly legitimates it.’’ Renee Fox, Annenberg Professor Emerita of the Social Sciences, University of Pennsylvania.