California Cures How The California Stem Cell Program Is Fighting Your Incurable Disease

Author : Reed Don C
Publisher : World Scientific
ISBN 13 : 9813231386
Total Pages : 352 pages
Book Rating : 4.82/5 ( download)

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Download or read book California Cures!: How The California Stem Cell Program Is Fighting Your Incurable Disease! written by Reed Don C and published by World Scientific. This book was released on 2018-03-16 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirteen years ago, America faced an epidemic of chronic disease: cancer, paralysis, blindness, arthritis, Alzheimer's disease, diabetes and more. But California voters said "YES!" to a $3 billion stem cell research program: the awkwardly-named California Institute for Regenerative Medicine (CIRM). Born into battle, the scrappy little state agency was immediately blocked by three years of anti-science lawsuits — but it defeated them all. And then? A quiet triumph. With a focused intensity like the Manhattan Project (but for peaceful purposes, not to build a bomb), scientists funded by CIRM took on the challenges: disease and disability called chronic: incurable. In a series of connected stories, accurate though written to entertain, "California Cures" relates a war: science against disease, with lives on the line. Think what it means for a paralyzed young man to recover the use of his hands, or for a formerly-blind mother to see her teenaged children — for the first time! Do you know the "bubble-baby" syndrome? Infants without a proper immune system typically die young; a common cold can kill. But for eighteen babies in a stem cell clinical trial, a different future: they were cured of their disease. No one can predict the pace of science, nor say when cures will come; but California is bringing the fight. The reader will meet the scientists involved, the women and men behind the microscope, and share their struggle. Above all, "California Cures" is a call for action. Washington may argue about the expense of health care (and who will get it), but California works to bring down the mountain of medical debt: stem cell therapies to ease suffering, and save lives. Will California build on success — and invest $5 billion more in stem cell research? "We have the momentum," says author Don C Reed, "We dare not stop short. Chronic disease threatens everyone — we are fighting for your family, and mine!" Contents: Introduction: Evangelina and the Golden State The Absolute Minimum You Need to Know First To Breathe, or Not to Breathe The Strongest Man in the World When the Dolphin Broke My Ear The Boy with Butterfly Skin The Great Baldness "Comb-Over" Replacement? "He Sees! He Sees!" Cop at the Window "Go West, Young (Wo)Man" — To a Biomed Career? And How Will You be Paying for that New Heart? The Answer to Cancer? A Political Obstacle to Heart Disease Cure? Your Friend, the Liver! "Bring 'em Back Alive" The Color of Fat Revenge for My Sister A Story with No Happy Ending? Aging and Stem Cells The "Impending Alzheimer's Healthcare Disaster" President Trump's Great Stem Cell Opportunity Leiningen's Ants and Parkinson's Disease On the Morality of Fetal Cell Research Democracy and Gloria's Knees Three Children, and the Eternal Flame Autism, Mini-Brains, and the Zika Virus Why "The Big Bang Theory" Matters to Me Musashi and the Two-Sword Solution "The Magnificent Seven" The Connecticut Commitment In Memory of Beau To Relocate Alligators, or Turn a Country on to Biomed? Whale Sharks and Outer Space Mr Science Goes to Washington? When Oklahoma is Not Ok James Bond and Melanoma Neurological Diseases vs. California Driving to the Storm Door into Tomorrow Stem Cell Battles — On Times Square? Annette, Richard Pryor, and Multiple Sclerosis Mike Pence, and Reproductive Servitude Motorcycle Wrecks and Complex Fractures Even Dracula Gets Arthritis Tugboat for Cure Wheelchair Warriors, Take Back Your Rights! Sickle Cell Dis

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9811213305
Total Pages : 369 pages
Book Rating : 4.04/5 ( download)

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Download or read book Revolutionary Therapies: How The California Stem Cell Program Saved Lives, Eased Suffering - And Changed The Face Of Medicine Forever written by Don C Reed and published by World Scientific. This book was released on 2020-03-04 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: For author Don C Reed, father of a paralyzed son, the California Institute for Regenerative Medicine (CIRM) is the greatest medical advance since penicillin.REVOLUTIONARY THERAPIES is Reed's third book about the $3 billion stem cell program.Voted into law in November 2004, CIRM is now running out of money.Should its funding be renewed? Thereby hangs a tale, or rather several dozen of them, for each of the book's 71 short chapters is framed by a yarn or vignette.The factual background is accurate, vetted by the scientists, but Reed's goal is clearly both entertainment and education.A favorite example is a little girl named Evie, imprisoned in a plastic bubble: her body's immune system did not work, and she would die outside. She joined a CIRM clinical trial ... Imagine how Evie's parents felt — when she got well.Some stories are comical, like 'How Stem Cell Research Saved My Car'; others surprising, like the comparison between politics and the giant crocodile Gustave; others are tragic or inspiring: but all point to this: More than 100 million Americans suffer chronic disease, causing mountains of medical debt — and the only way to reduce that expense ($3 trillion last year) — is cure.Related Link(s)

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9811261431
Total Pages : 336 pages
Book Rating : 4.35/5 ( download)

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Download or read book Science, Politics, Stem Cells And Genes: California's War On Chronic Disease written by Don C Reed and published by World Scientific. This book was released on 2023-02-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is there a way to fight back against 'incurable' disease? California thought so — and put its money where its mind was — three billion dollars' worth! And when that was gone, how about five and a half billion dollars more — to build and expand the California Institute for Regenerative Medicine?For some, science excites; it is the great adventure, to challenge the impossible: like a real-life battle with a giant squid, or the proposed disassembly of the Eiffel Tower, or ejecting from a jet in the sky, from a height greater than Mount Everest.For others, regenerative medicine is a mystery — could the urge to do murder have a genetic cause — which might be reduced?And for everyone, there is the fight to protect our loved ones' lives— 133 million of us, suffering from chronic disease — from America alone, a colossal cost of $3 trillion dollars last year.An epic battle, 'Science, Politics, Stem Cells and Genes: CALIFORNIA'S WAR ON CHRONIC DISEASE' takes the reader behind the scenes.An award-winning teacher, Reed shares science in stories — including the systematic assault on Alzheimer's disease, cancer, autism, epilepsy, liver failure, schizophrenia, obesity, stroke, sickle cell, arthritis, blindness, paralysis, kidney failure, ALS, aging, and much, much more.Readers can expect a greater understanding of the intricate adventure of stem cell research, as well as the political wrestling it took to make progress possible — that California's effort may benefit the world.From early research to clinical trials, America should take pride in the accomplishments of the California Institute for Regenerative Medicine.Read on.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309265908
Total Pages : 177 pages
Book Rating : 4.04/5 ( download)

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Download or read book The California Institute for Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2013-03-27 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The California Institute for Regenerative Medicine (CIRM) was created in 2005 by The California Stem Cell Research and Cures Act (Proposition 71) to distribute $3 billion in state funds for stem cell research. The passage of Proposition 71 by the voters of California occurred at a time when federal funding for research involving human embryonic stem cells was uncertain, given the ethical questions raised by such research. During its initial period of operations, CIRM has successfully and thoughtfully provided more than $1.3 billion in awards to 59 California institutions, consistent with its stated mission. As it transitions to a broadened portfolio of grants to stimulate progress toward its translational goals, the Institute should obtain cohesive, longitudinal, and integrated advice; restructure its grant application review process; and enhance industry epresentation in aspects of its operations. CIRM's unique governance structure, while seful in its initial stages, might diminish its effectiveness moving forward. The California Institute for Regenerative Medicine: Science, Governance, and the Pursuit of Cures recommends specific steps to enhance CIRM's organization and management, as well as its scientific policies and processes, as it transitions to the critical next stages of its research and development program.

Author : Khawaja Husnain Haider
Publisher : World Scientific
ISBN 13 : 981120554X
Total Pages : 281 pages
Book Rating : 4.45/5 ( download)

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Download or read book Stem Cells: From Hype To Hope written by Khawaja Husnain Haider and published by World Scientific. This book was released on 2020-03-19 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, stem cells have progressed from merely a concept to a vibrant field of regenerative medicine which is aimed at addressing the root cause of the problem rather than conventional methods of intervention that mostly provide symptomatic relief.Stem cell therapy either alone or in combination with the other established treatment strategies is a hope for patients who suffer from the 'incurable' diseases such as Alzheimer, diabetes, myocardial infarction etc. Besides aspirations in the clinical perspective, stem cells provide excellent in vitro disease models for drug development.Given the significance of the field, the proposed book will be a compilation of the bench experience of experts from various research labs involved in the cutting edge area of stem cell research.

Author : Don C. Reed
Publisher : World Scientific
ISBN 13 : 9814618292
Total Pages : 432 pages
Book Rating : 4.98/5 ( download)

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Download or read book Stem Cell Battles: Proposition 71 and Beyond written by Don C. Reed and published by World Scientific. This book was released on 2015-10-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: ' This is a one-of-a-kind book: combining easy-to-understand science, in-the-trenches political warfare, and inspirational stories. It aims to give hope to individuals and families who suffer from chronic disease or disability; to point out how ordinary people can make an extraordinary difference in the battle to ease suffering and save lives through supporting medical research; to share in “people talk” some of the amazing progress already achieved in the new field of stem cell research; to show how even such a magnificent success as the California stem cell program is under constant attack from ideological groups; to offer medical research as a force for international cooperation; to suggest how cure research lessens the need for the mountainous costs of endless care. Unparalleled background: the author has been involved in virtually every important stem cell battle (state, national, and international) since embryonic stem cell research began. The author works closely with Robert N. Klein, sponsor of the California stem cell program, the largest source of such stem cell research funding in the world. In addition, the author is an award-winning teacher as well as writer, and seeks to entertain as well as educate. His book is not only substantive, but also fun. The book would be a treasured gift: for anyone suffering an “incurable” illness or who is a caregiver for a loved one; for a college student considering a rewarding career in biomedicine; for scientists who want to protect and enhance their research funding; and for anyone who wants to see government respond to the needs of its citizenry. Chronic disease and disability are a prison: cure is the triumphant escape — wheelchairs should be for temporary occupancy only. Contents:Foreword by Christopher ReeveAcknowledgementsThe World''s Deadliest KillersThe Naked Face of HateTo Clone, or Not to Clone?Season of StormsThe Trial(S) of the California Stem Cell ProgramWhen Changing the World, What Do You Do First?Battles With a FriendTime-Lapse ScriptographyIdeology, Science or Bible Quoting Vampires?Joan of Arc, and the Republican Stem Cell Reversal?Deadly DefinitionsWhat are We Fighting for?Suffer Little ChildrenKlein Must Resign!Last Day in the Wolverine StateGetting Up in the Morning and Going to — Washington?The Boy Who Loved Stanford Too MuchStem Cell Summit, Stem Cell WorldHow Not to Have Sex in a Personhood StateFighting the Killers: Leukemia and CancerThe Thief of MemoryThe Anti-Science SocietyStem Cell ThanksgivingSwimming from AlcatrazBridge to a New LifeSkidding on IceHow to Mend a Broken HeartHelen Keller and Stem Cell ResearchHow to Mend a Broken HeartWhy We Can''t Afford Not to Cure ParalysisThe War We Must Not LoseIn Which I Get CancerSickle-Cell Anemia and the Politics of PainMowgli and the Matrix: A Year in the Life of the California Stem Cell ProgramTo Whom Goes the Kingdom?The Liver ListThe Will of ConnecticutChampions Find a WayDisenfranchise the Disabled?Adventures in Intellectual PropertySpartacus Fights Back Against StrokeDiabetes Going Down?Jamie Thomson, or, How Do You Follow an Act of Genius?Sherley V SebeliusThe Woman Who Would Not be SilencedThe Gorilla Gynecologist, or, the Pera-Chen Anti-Urinary-Incontinence MethodTurning Over Rocks: The Battle for Paralysis CureIn Memory Still Green: The Passing of Three GiantsInvitation to MexicoOf Presidents, and the Valley of DeathLittle Hoover and the Institute of MedicineStudying the Moon, Looking Through a StrawThe Great Nebraska CompromiseStem Cell TourismThe Man Who Could Fly Without a PlaneThief of LivesSingapore, Biopolis, and the Power of the SmallSingapore ScientistsFighters Against Parkinson''sInternational FriendsA Texas Miracle, or Thirty-TwoThe Stem Cell Musketeers of BrazilAdventures in ChinaProfessor Forever and the Giant SquidA Double Baker''s Dozen of Disease Team Grants?The Greatest Speech You Never HeardA Stem Cell Mystery: The Resignation of Mahendra RaoArthritis and the Fifty StatesWould You Drink from a Fountain of Youth?When Things Go RightWhere Did the Money Go? (and a New Year''s Delight at the End...)The End?Appendices:Interview with Lim Chuan Poh, Chairman of A*Star and BiopolisAn Interview with Hans KeirsteadInterview with Bob Klein Keywords:Stem Cell Research;Cure;Roman Reed Spinal Cord Injury Research Act;Don C Reed;Americans for Cures Foundation;Proposition 71;Bob Klein;California Institute for Regenerative Medicine (CIRM) “A well-written book on a technical and challenging subject, Stem Cell Battles is a real page-turner. Don Reed writes from a layman''s point of view; his credentials and advocacy experience position him to thoroughly cover his subject and present the subject of stem cell research in an interesting and entertaining way. The book is appropriate for students doing research, for any general reader, and for anyone who is or knows the one in two Americans with an incurable disease or disability. The book fills a gap in public library collections, and is useful in academic collections as well because it covers the subject very well. The author carefully and thoroughly footnotes and documents his material; the reader can see the reliability of the subject coverage, and know here to follow up as interested.” Sandi Pantages Fremont, California "Impassioned advocacy for stem cell research … recommended for anyone interested in the California Institute for Regenerative Medicine, its origins, and its accomplishments so far …" Dr James Till co-recipient (with Ernest McCulloch) of Lasker Award Toronto, Canada "It''s a highly recommended pick for any involved in stem cell concerns; whether it be from a scientist''s perspective, a politician''s viewpoint, or from a patient seeking relief. Its focus on California achievements, in particular, lends to a discussion that juxtaposes the personal with the political in a rare, wide-ranging discussion that no health collection should be without. Add insights into how ordinary people can help and you have a key acquisition not to be missed by readers with any degree of interest or curiosity in stem cell research''s promises, controversies, and very human concerns; or by acquisition librarians who will appreciate its fresh, new perspective on the subject." Midwest Book Review "Reed''s voice is warm, optimistic, and determined, while he acknowledges that such political battles are hard on both patients and caregivers. His attitude of calm hope in the face of obstacles both public and personal is admirable and encouraging. Stem Cell Battles is a prime example of how a small group of people can bring about significant change for many. It''s a valuable book for that reason alone, but the human stories Reed includes make it more so." Foreword Reviews "As founder of the Student Society for Stem Cell Research with chapters throughout the United States and the world, I encourage young men and women to enter stem cell research and pursue a career in regenerative medicine. Everyone should read Don Reed''s new book, STEM CELL BATTLES, which is an inspiring account, with the pages bounded by a father''s love for his son and the most powerful of human principles, hope. The treatise is a historical account of California''s stem cell program and the development of a nascent field that is united by humanity''s quest for cures. I have known Don for many years and we have worked together to help pass pro-research legislation. This book impresses upon the reader the impact of working with visionaries such as Bob Klein, who developed Proposition 71 and led it to become the California Institute for Regenerative Medicine. Because of that initiative, we are closer to cures in various areas like diabetes and macular degeneration." Joe Riggs Founder of the 19-nation organization Students for Stem Cell Research "This book is like no other; a monumental achievement! Due to 20 years of Parkinson''s disease I am too weak to hold it for very long, so it will take the rest of my life to finish it. It contains the personal stories of people with every known disease and disability, all of which could someday be helped or cured by stem cell research. You cannot read it without becoming inspired to engage in the battle for medical research. As Don has documented, it is a difficult struggle but eventually we will prevail. It has been a great honor to have known this great man and advocate." Rayilyn Lee Brown Surprise, Arizona, USA "This solid primer should be useful to anyone interested in stem cells and their potential to change the world." Kirkus Reviews '

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309672988
Total Pages : 127 pages
Book Rating : 4.86/5 ( download)

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Download or read book Exploring Novel Clinical Trial Designs for Gene-Based Therapies written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-27 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the workshop discussed patient recruitment and selection for gene-based clinical trials, explored how the safety of new therapies is assessed, reviewed the challenges involving dose escalation, and spoke about ethical issues such as informed consent and the role of clinicians in recommending trials as options to their patients. The workshop also included discussions of topics related to gene therapies in the context of other available and potentially curative treatments, such as bone marrow transplantation for hemoglobinopathies. This publication summarizes the presentation and discussion of the workshop.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921484X
Total Pages : 383 pages
Book Rating : 4.41/5 ( download)

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Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Author : Tony Robbins
Publisher : Simon and Schuster
ISBN 13 : 1982121734
Total Pages : 720 pages
Book Rating : 4.30/5 ( download)

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Download or read book Life Force written by Tony Robbins and published by Simon and Schuster. This book was released on 2022-02-08 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSTANT #1 NEW YORK TIMES BESTSELLER Transform your life or the life of someone you love with Life Force—the newest breakthroughs in health technology to help maximize your energy and strength, prevent disease, and extend your health span—from Tony Robbins, author of the #1 New York Times bestseller Money: Master the Game. What if there were scientific solutions that could wipe out your deepest fears of falling ill, receiving a life-threatening diagnosis, or feeling the effects of aging? What if you had access to the same cutting-edge tools and technology used by peak performers and the world’s greatest athletes? In a world full of fear and uncertainty about our health, it can be difficult to know where to turn for actionable advice you can trust. Today, leading scientists and doctors in the field of regenerative medicine are developing diagnostic tools and safe and effective therapies that can free you from fear. In this book, Tony Robbins, the world’s #1 life and business strategist who has coached more than fifty million people, brings you more than 100 of the world’s top medical minds and the latest research, inspiring comeback stories, and amazing advancements in precision medicine that you can apply today to help extend the length and quality of your life. This book is the result of Robbins going on his own life-changing journey. After being told that his health challenges were irreversible, he experienced firsthand how new regenerative technology not only helped him heal but made him stronger than ever before. Life Force will show you how you can wake up every day with increased energy, a more bulletproof immune system, and the know-how to help turn back your biological clock. This is a book for everyone, from peak performance athletes, to the average person who wants to increase their energy and strength, to those looking for healing. Life Force provides answers that can transform and even save your life, or that of someone you love.

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309498511
Total Pages : 103 pages
Book Rating : 4.17/5 ( download)

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Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.