Bone Regulators And Osteoporosis Therapy

Author : Paula H. Stern
Publisher : Springer Nature
ISBN 13 : 3030573788
Total Pages : 518 pages
Book Rating : 4.82/5 ( download)

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Download or read book Bone Regulators and Osteoporosis Therapy written by Paula H. Stern and published by Springer Nature. This book was released on 2020-11-28 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.

Author : Pauline M. Camacho
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781786195
Total Pages : 246 pages
Book Rating : 4.93/5 ( download)

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Download or read book Osteoporosis written by Pauline M. Camacho and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a practical and comprehensive guide to the diagnosis and management of osteoporosis. The book covers all aspects of osteoporosis, from pathophysiology to diagnostic tests and therapies, and includes actual case studies with teaching points. Separate chapters focus on vitamin D deficiency and workup and recognition of secondary causes of bone loss. Coverage of treatment includes tailoring therapy to individual patients, determining the success of therapy, what to do when therapy fails, and future therapeutic options. The authors review the latest evidence and provide annotated references so readers can examine the methodology, results, and conclusions of the studies.

Author : Elaine Dennison
Publisher :
ISBN 13 : 9783030781293
Total Pages : 0 pages
Book Rating : 4.91/5 ( download)

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Download or read book Osteoporosis Treatment written by Elaine Dennison and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical overview of osteoporosis for the wide spectrum of clinicians that might encounter the osteoporotic patient. Concise and well-structured chapters examine the public health importance of the condition, the current treatment gap, how to identify individuals who would benefit from treatment, bone turnover and how this can be modified by osteoporosis therapies, adjuvant lifestyle modification, the calcium and vitamin D story, antiresorptive therapies, anabolic therapies, emerging therapies, adherence and compliance with therapy and the perception of fracture risk. Osteoporosis Treatment: A Clinical Overview meets the need for a book that improves awareness of this major public health problem and possible therapeutic approaches. Primary care physicians, endocrinologists, rheumatologists, orthopaedic surgeons and those providing specialist care for the elderly will all benefit from this highly accessible and informative guide to treating osteoporosis.

Author : Michael Kleerekoper
Publisher : CRC Press
ISBN 13 : 9781842140307
Total Pages : 130 pages
Book Rating : 4.02/5 ( download)

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Download or read book Drug Therapy for Osteoporosis written by Michael Kleerekoper and published by CRC Press. This book was released on 2004-12-02 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone replacement is clearly indicated for the prevention and treatment of osteoporosis. Although its importance in treating this disease is no longer questioned, much remains to be fully understood about its effective application in practice. Drug Therapy for Osteoporosis examines what is known about the progress of osteoporosis and describes the impact of hormone replacement therapy. The author reviews the option for using SERMs as opposed to conventional HRT regimens, discusses not only the effectiveness of treatment but also the recommended duration, and provides clear guidelines on the laboratory evaluation of osteoporosis.

Author : Stuart Silverman
Publisher : Springer
ISBN 13 : 3319236393
Total Pages : 349 pages
Book Rating : 4.91/5 ( download)

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Download or read book The Duration and Safety of Osteoporosis Treatment written by Stuart Silverman and published by Springer. This book was released on 2015-12-29 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.

Author : Benjamin Z. Leder
Publisher : Springer Nature
ISBN 13 : 3319692879
Total Pages : 518 pages
Book Rating : 4.76/5 ( download)

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Download or read book Osteoporosis written by Benjamin Z. Leder and published by Springer Nature. This book was released on 2020-01-31 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, including 300,000 hip fractures. Mortality rates after hip fracture approach 25%, with another 50% of patients experiencing a major decrease in their prior level of independence and quality of life. Despite the wide prevalence and severe consequences of osteoporosis, it remains a disorder that is severely under-diagnosed and treated. In this context, specialists and primary care physicians alike are having increasing difficulty keeping up with the rapid changes to the field and incorporating these advances to clinical care. In the years since the last edition of this book was published, the osteoporosis field has changed drastically. In addition to revising and updating existing chapters and removing a few that are no longer as relevant, new chapters discuss an advanced understanding of the cellular and molecular mechanisms underlying the disorder, the introduction of new diagnostic imaging techniques, a more nuanced appreciation of the risks and benefits of osteoporosis therapies, and the introduction of two new classes of osteoporosis medications. Following the format of the second edition, and including helpful key points at the opening of each chapter, this text will present a comprehensive overview of both the basic and clinical concepts relating to each topic, when appropriate. Chapter authors were chosen based on their high level of expertise and leadership in the field. Taken together, this text should thus be of great interest to physicians of multiple specialties, allied health professionals, as well as basic and clinical researchers.

Author : Yannis Dionyssiotis
Publisher : BoD – Books on Demand
ISBN 13 : 9535120271
Total Pages : 178 pages
Book Rating : 4.78/5 ( download)

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Download or read book Advances in Osteoporosis written by Yannis Dionyssiotis and published by BoD – Books on Demand. This book was released on 2015-03-04 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: A balanced regulation of bone formation and resorption in the healthy individual is required for a healthy bone. On the other side, there are many factors which can lead to alterations in bone density and microarchitecture. Menopause is a condition which can increase the remodeling process in favor of resorption. Moreover, there are also some diseases, i.e. chronic kidney bone disease, that increase the possibility of fractures and the subsequent disability leading to increased mortality. However, it is clear that drugs are an essential element of the therapy and this issue is analyzed extensively in this book. Some novel pathophysiological mechanisms are also presented, offering advanced knowledge to the reader. The book includes chapters from scientific departments and researchers from all over the world.

Author : James F. Whitfield
Publisher : CRC Press
ISBN 13 : 1482234033
Total Pages : 288 pages
Book Rating : 4.39/5 ( download)

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Download or read book Anabolic Treatments for Osteoporosis written by James F. Whitfield and published by CRC Press. This book was released on 2013-11-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at increasing bone mass. However, exciting new developments are on the verge of changing the treatment of this debilitating disorder. Two anabolic agents, the parathyroid hormone (PTH) and the fluoride ion, show tremendous promise as tools for building and retaining bone - with no adverse side effects. Anabolic Treatments for Osteoporosis is a comprehensive account of the latest studies that have been carried out on these two agents, and a thorough assessment of their prospects as osteoporosis therapeutics. This unique book combines basic science and up-to-date clinical data to present a complete picture of this breakthrough in the treatment of a globally significant health issue.

Author : Margarita Valdés-Flores
Publisher : BoD – Books on Demand
ISBN 13 : 9535110667
Total Pages : 292 pages
Book Rating : 4.68/5 ( download)

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Download or read book Topics in Osteoporosis written by Margarita Valdés-Flores and published by BoD – Books on Demand. This book was released on 2013-05-15 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis affects the osteo-articular system. However, there are hormonal, kidney related, gastrointestinal and neuromuscular factors among other, that can be involved in the etiopathogenesis of the disease. In the other hand, for osteoporosis prevention there are many lifestyle conditions that are very important, as dietary habits, physical activity, drugs and caffeine intake, smoking, associated diseases, etc. Based on the above, treatment and prevention of osteoporosis have to be addressed in a multidisciplinary and integral approach. The knowledge about bone metabolism and the related disorders represents an extensive field that is currently increasing through many investigations conducted in the world. The purpose of this book is to show several reviews and original investigations related with osteoporosis.

Author : Piet Geusens
Publisher : Springer Science & Business Media
ISBN 13 : 0857294024
Total Pages : 262 pages
Book Rating : 4.29/5 ( download)

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Download or read book Osteoporosis in Clinical Practice written by Piet Geusens and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: When I was a young intern in internal medicine,osteoporosis was defined mainly as a fracture occurring in elderly people. However,although plain X-ray examination was recognized as an insensitive way to detect osteoporosis, hypodense bone was already considered as the reflection of the disease. Over the past 20 years, con siderable progress has been accomplished. In terms of prevalence, incidence, risk factors, and the burden of osteoporosis and low-energy fracture, we can appreciate the magnitude of the problem and its impact on quality oflife. Weare wellaware that vertebral fracture, which can be acutely associated with a low clinical expression, leads to significant long-term impairments. The costs for the individual and for the health budget, Le. society,are estimated better. Wenow have a clear definition of the disease, such as low bone mass and architectural defects, resulting in increased fragility. For the former part of the definition, the clinician can use accurate and pre cise tools allowing them to distinguish how their patient's bone mineral content differs from that of a young healthy population in which fracture occurs very rarely. For the second series of fragility determinants, i. e. structure, methods are in rapid progress and will provide information to clinicians on these variables in the near future. Basicand clinical research have allowed major improvements in the understand ing of the pathophysiology of the disease. Newgenes implicated in lowand/or high bone mass have been characterized.