Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance

Author : John Wade
Publisher : Frontiers E-books
ISBN 13 : 2889191788
Total Pages : 140 pages
Book Rating : 4.89/5 ( download)

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Download or read book Biophysically based Computational Models of Astrocyte ~ Neuron Coupling and their Functional Significance written by John Wade and published by Frontiers E-books. This book was released on 2014-03-21 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscientists are increasingly becoming more interested in modelling brain functions where capturing the biophysical mechanisms underpinning these functions requires plausible models at the level of neuron cells. However, cell level models are still very much in the embryo stage and therefore there is a need to advance the level of biological realism at the level of neurons/synapses. Recent publications have highlighted that astrocytes continually exchange information with multiple synapses; if we are to fully appreciate this dynamic and coordinated interplay between these cells then more research on bidirectional signalling between astrocytes and neurons is required. A better understanding of astrocyte-neuron cell coupling would provide the building block for studying the regulatory capability of astrocytes networks on a large scale. For example, it is believed that local and global signalling via astrocytes underpins brain functions like synchrony, learning, memory and self repair. This Research Topic aims to report on current research work which focuses on understanding and modelling the interaction between astrocytes and neurons at the cellular level (Bottom up) and at network level (Top down). Understanding astrocytic regulation of neural activity is crucial if we are to capture how information is represented and processed across large neuronal ensembles in humans.

Author : Sharon Crook
Publisher : Frontiers Media SA
ISBN 13 : 2889638383
Total Pages : 279 pages
Book Rating : 4.83/5 ( download)

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Download or read book Reproducibility and Rigour in Computational Neuroscience written by Sharon Crook and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Dietmar Plenz
Publisher : John Wiley & Sons
ISBN 13 : 3527651020
Total Pages : 734 pages
Book Rating : 4.23/5 ( download)

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Download or read book Criticality in Neural Systems written by Dietmar Plenz and published by John Wiley & Sons. This book was released on 2014-04-14 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurowissenschaftler suchen nach Antworten auf die Fragen, wie wir lernen und Information speichern, welche Prozesse im Gehirn verantwortlich sind und in welchem Zeitrahmen diese ablaufen. Die Konzepte, die aus der Physik kommen und weiterentwickelt werden, können in Medizin und Soziologie, aber auch in Robotik und Bildanalyse Anwendung finden. Zentrales Thema dieses Buches sind die sogenannten kritischen Phänomene im Gehirn. Diese werden mithilfe mathematischer und physikalischer Modelle beschrieben, mit denen man auch Erdbeben, Waldbrände oder die Ausbreitung von Epidemien modellieren kann. Neuere Erkenntnisse haben ergeben, dass diese selbstgeordneten Instabilitäten auch im Nervensystem auftreten. Dieses Referenzwerk stellt theoretische und experimentelle Befunde internationaler Gehirnforschung vor zeichnet die Perspektiven dieses neuen Forschungsfeldes auf.

Author : Emili Balaguer-Ballester
Publisher : Frontiers Media SA
ISBN 13 : 2889454371
Total Pages : 152 pages
Book Rating : 4.72/5 ( download)

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Download or read book Metastable Dynamics of Neural Ensembles written by Emili Balaguer-Ballester and published by Frontiers Media SA. This book was released on 2018-03-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classical view of neural computation is that it can be characterized in terms of convergence to attractor states or sequential transitions among states in a noisy background. After over three decades, is this still a valid model of how brain dynamics implements cognition? This book provides a comprehensive collection of recent theoretical and experimental contributions addressing the question of stable versus transient neural population dynamics from complementary angles. These studies showcase recent efforts for designing a framework that encompasses the multiple facets of metastability in neural responses, one of the most exciting topics currently in systems and computational neuroscience.

Author : Carl Faingold
Publisher : Academic Press
ISBN 13 : 0124158641
Total Pages : 537 pages
Book Rating : 4.41/5 ( download)

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Download or read book Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Author : Věra Kůrková
Publisher : Springer
ISBN 13 : 303001424X
Total Pages : 866 pages
Book Rating : 4.47/5 ( download)

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Download or read book Artificial Neural Networks and Machine Learning – ICANN 2018 written by Věra Kůrková and published by Springer. This book was released on 2018-10-02 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set LNCS 11139-11141 constitutes the refereed proceedings of the 27th International Conference on Artificial Neural Networks, ICANN 2018, held in Rhodes, Greece, in October 2018. The papers presented in these volumes was carefully reviewed and selected from total of 360 submissions. They are related to the following thematic topics: AI and Bioinformatics, Bayesian and Echo State Networks, Brain Inspired Computing, Chaotic Complex Models, Clustering, Mining, Exploratory Analysis, Coding Architectures, Complex Firing Patterns, Convolutional Neural Networks, Deep Learning (DL), DL in Real Time Systems, DL and Big Data Analytics, DL and Big Data, DL and Forensics, DL and Cybersecurity, DL and Social Networks, Evolving Systems – Optimization, Extreme Learning Machines, From Neurons to Neuromorphism, From Sensation to Perception, From Single Neurons to Networks, Fuzzy Modeling, Hierarchical ANN, Inference and Recognition, Information and Optimization, Interacting with The Brain, Machine Learning (ML), ML for Bio Medical systems, ML and Video-Image Processing, ML and Forensics, ML and Cybersecurity, ML and Social Media, ML in Engineering, Movement and Motion Detection, Multilayer Perceptrons and Kernel Networks, Natural Language, Object and Face Recognition, Recurrent Neural Networks and Reservoir Computing, Reinforcement Learning, Reservoir Computing, Self-Organizing Maps, Spiking Dynamics/Spiking ANN, Support Vector Machines, Swarm Intelligence and Decision-Making, Text Mining, Theoretical Neural Computation, Time Series and Forecasting, Training and Learning.

Author : Vladimir Parpura
Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.21/5 ( download)

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Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Author : Enrica Boda
Publisher : Frontiers Media SA
ISBN 13 : 2889762858
Total Pages : 255 pages
Book Rating : 4.59/5 ( download)

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Download or read book The Role of Astroglia and Oligodendroglia in CNS Development, Plasticity, and Disease – Novel Tools and Investigative Approaches written by Enrica Boda and published by Frontiers Media SA. This book was released on 2022-05-31 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Ioan Opris
Publisher : Frontiers Media SA
ISBN 13 : 2889456153
Total Pages : 403 pages
Book Rating : 4.54/5 ( download)

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Download or read book Augmentation of Brain Function: Facts, Fiction and Controversy written by Ioan Opris and published by Frontiers Media SA. This book was released on 2018-09-14 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Volume II is entitled “Neurostimulation and pharmacological approaches”. This volume describes augmentation approaches, where improvements in brain functions are achieved by modulation of brain circuits with electrical or optical stimulation, or pharmacological agents. Activation of brain circuits with electrical currents is a conventional approach that includes such methods as (i) intracortical microstimulation (ICMS), (ii) transcranial direct current stimulation (tDCS), and (iii) transcranial magnetic stimulation (TMS). tDCS and TMS are often regarded as noninvasive methods. Yet, they may induce long-lasting plastic changes in the brain. This is why some authors consider the term “noninvasive” misleading when used to describe these and other techniques, such as stimulation with transcranial lasers. The volume further discusses the potential of neurostimulation as a research tool in the studies of perception, cognition and behavior. Additionally, a notion is expressed that brain augmentation with stimulation cannot be described as a net zero sum proposition, where brain resources are reallocated in such a way that gains in one function are balanced by costs elsewhere. In recent years, optogenetic methods have received an increased attention, and several articles in Volume II cover different aspects of this technique. While new optogenetic methods are being developed, the classical electrical stimulation has already been utilized in many clinically relevant applications, like the vestibular implant and tactile neuroprosthesis that utilizes ICMS. As a peculiar usage of neurostimulation and pharmacological methods, Volume II includes several articles on augmented memory. Memory prostheses are a popular recent development in the stimulation-based BMIs. For example, in a hippocampal memory prosthesis, memory content is extracted from hippocampal activity using a multiple-input, multiple-output non-linear dynamical model. As to the pharmacological approaches to augmenting memory and cognition, the pros and cons of using nootropic drugs are discussed.

Author : Christoph von der Malsburg
Publisher : MIT Press
ISBN 13 : 0262014718
Total Pages : 367 pages
Book Rating : 4.17/5 ( download)

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Download or read book Dynamic Coordination in the Brain written by Christoph von der Malsburg and published by MIT Press. This book was released on 2010 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nervous systems do not live by the rate code alone. The ceaseless activities of groups of neurons are choregraphed into waves, oscillations, synchronized rhythms, and transient coalitions; it is these that underlie behavior, memory, and conscious perception. This exuberant manifesto masterfully summarizes and reflects upon the relevant evidence of these patterns from all manner of brains, small and large." --