Analysis Of Cardiac Development

Author : Rafael Beyar
Publisher : John Wiley & Sons
ISBN 13 : 1573317470
Total Pages : 241 pages
Book Rating : 4.74/5 ( download)

DOWNLOAD NOW!

Download or read book Analysis of Cardiac Development written by Rafael Beyar and published by John Wiley & Sons. This book was released on 2010-03-22 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, the result of three days of interactive sessions among world leaders in the cardiac sciences, summarizes the most up-to-date information about development and cardiogenesis signaling in cell-based therapy, as well as developmental aspects of the formation of the embryonic heart, including the effect of mechanical load on differentiation. Other topics covered include: signaling and repair strategies, cell and gene therapy for the treatment of postmyocardial infarction, signaling, vascularization methods in engineering embryonic cardiac tissue, and molecular methods to improve survival of human embryonic stem cell–derived cardiomyocytes; developmental and evolutional cardiology; novel strategies for treatment of atrial fibrillation and channel molecular physiology in remodeling and hypertrophy; multiscale modeling for metabolism and flows, including force development, mechanics of cardiac contraction, and ATP supply and demand aspects; aging, interactions, and interference aspects include fibroblast-myocyte-capillary communications, nonuniformities in contraction, calcium channels as oxygen sensors, and epigenetics of heart failure; and macroscale phenomena and clinical aspects, including various clinical aspects of modern cardiology such as navigation methods for cardiac interventions and control of cardiac function by changes in energetic demand. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Author : Hongyi Sun
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Gene Investigation and Analysis in Cardiac Development written by Hongyi Sun and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Alexandre Tanios Soufan
Publisher :
ISBN 13 :
Total Pages : 95 pages
Book Rating : 4.82/5 ( download)

DOWNLOAD NOW!

Download or read book Three Dimensional Visualization and Analysis of Cardiac Development written by Alexandre Tanios Soufan and published by . This book was released on 2006 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.19/5 ( download)

DOWNLOAD NOW!

Download or read book Analysis of Gene Expression in Cardiac Development and Disease written by and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Richard P. Harvey
Publisher : Gulf Professional Publishing
ISBN 13 : 9780123298607
Total Pages : 574 pages
Book Rating : 4.01/5 ( download)

DOWNLOAD NOW!

Download or read book Heart Development written by Richard P. Harvey and published by Gulf Professional Publishing. This book was released on 1999 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...

Author : Margaret L. Kirby
Publisher : Oxford University Press
ISBN 13 : 019972086X
Total Pages : 288 pages
Book Rating : 4.66/5 ( download)

DOWNLOAD NOW!

Download or read book Cardiac Development written by Margaret L. Kirby and published by Oxford University Press. This book was released on 2007-03-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.

Author : Bohuslav Ost'ádal
Publisher : Springer Science & Business Media
ISBN 13 : 146150967X
Total Pages : 296 pages
Book Rating : 4.77/5 ( download)

DOWNLOAD NOW!

Download or read book Cardiac Development written by Bohuslav Ost'ádal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. This book is based on contributions presented at the international symposium The Developing Heart in Prague in May 2000. It is our contention that the biological, electrophysiological, morphological, functional, biochemical and functional approaches employed by distinguished scientists worldwide will provide the reader with a global picture for changes characterizing the developing heart. It should stimulate the curiosity of cardiovascular scientists in gaining insight into the mechanisms of normal and pathological development.

Author : David Muren Hwang
Publisher : National Library of Canada = Bibliothèque nationale du Canada
ISBN 13 : 9780612414433
Total Pages : 368 pages
Book Rating : 4.34/5 ( download)

DOWNLOAD NOW!

Download or read book Analysis of Gene Expression in Cardiac Development and Disease [microform] written by David Muren Hwang and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1998 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Nadia Rosenthal
Publisher : Academic Press
ISBN 13 : 0123813336
Total Pages : 1126 pages
Book Rating : 4.36/5 ( download)

DOWNLOAD NOW!

Download or read book Heart Development and Regeneration written by Nadia Rosenthal and published by Academic Press. This book was released on 2010-05-28 with total page 1126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. Authored by world experts in heart development and disease New research on epigenetic modifiers in cardiac development Comprehensive coverage of stem cells and prospects for cardiac regeneration Up-to-date research on transcriptional and proteomic circuits in cardiac disease Full-color, detailed illustrations

Author : David Muren Hwang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.63/5 ( download)

DOWNLOAD NOW!

Download or read book Analysis of Gene Expression in Cardiac Development and Disease written by David Muren Hwang and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Large-scale partial sequencing of randomly selected cDNA clones to generate expressed sequence tags (ESTs) is an efficient means of discovering novel genes and characterizing transcription in different tissues. To characterize gene expression and its changes in cardiac development and disease, an EST project was initiated using adult and fetal human heart cDNA libraries. Generation of 3,874 ESTs from an adult heart library, representing the first catalogue of genes expressed in the cardiovascular system, revealed that approximately half of all transcripts represented genes of unknown function. Analysis of the remaining half of transcripts representing known genes demonstrated expression patterns consistent with physiologic function of the heart. Comparison of these patterns with those derived from 2,244 ESTs generated from fetal heart, and with patterns obtained from other tissues, found several differences in gene expression between fetal and adult heart suggestive of a rapidly growing, less differentiated phenotype in the fetal heart relative to the adult heart. Further acquisition of larger numbers of ESTs from nine cardiac cDNA libraries, coupled with development of new strategies for data analysis, allowed for detailed prediction of individual genes exhibiting differential expression in cardiac development and disease. These strategies were applied to analyze gene expression in hypertrophic failing heart, and to study the expression of cell cycle regulators in cardiac development and hypertrophy. In the former analysis, a total of 64 genes was predicted to be differentially expressed in cardiac hypertrophy. Supporting the validity of these predictions, RT-PCR analysis of 12 of these genes confirmed 11 to be differentially expressed. In the latter analysis, transcripts of cell cycle regulators were suggested to be differentially expressed between fetal and adult hearts. Subsequent ' in vitro' analyses confirmed down-regulation of S- and G2/M-phase regulators in adult heart relative to fetal heart, and also found re-induction of several S-phase (e.g., cyclin A, PCNA), but not G2/M-phase (e.g., cyclin B, cdc2), regulators in hypertrophy. These results extend, at a molecular level, current understanding of cardiovascular function, while suggesting several new avenues of investigation. Further, they demonstrate the power of EST-based expression analyses for exploring questions of cardiovascular biology and medicine.