Alzheimers Disease And Infectious Causes

Author : Elaine A. Moore
Publisher : McFarland
ISBN 13 : 1476678618
Total Pages : 233 pages
Book Rating : 4.10/5 ( download)

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Download or read book Alzheimer's Disease and Infectious Causes written by Elaine A. Moore and published by McFarland. This book was released on 2020-04-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease.

Author : Elaine A. Moore
Publisher : McFarland
ISBN 13 : 1476638918
Total Pages : 233 pages
Book Rating : 4.11/5 ( download)

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Download or read book Alzheimer's Disease and Infectious Causes written by Elaine A. Moore and published by McFarland. This book was released on 2020-04-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease.

Author : J. Miklossy
Publisher : IOS Press
ISBN 13 : 1614997063
Total Pages : 420 pages
Book Rating : 4.61/5 ( download)

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Download or read book Handbook of Infection and Alzheimer's Disease written by J. Miklossy and published by IOS Press. This book was released on 2017-03-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is one of the biggest emerging public health problems in the world. Although the last four decades have yielded important insights into the pathogenesis of Alzheimer’s disease, its cause is still unclear, and if it is not discovered the world will face an unprecedented healthcare problem by the middle of this century. In recent years, evidence of the microbial origin of various chronic inflammatory disorders – including several neurodegenerative, neuropsychiatric and other systemic disorders – has been steadily growing. Accumulating new and historic observations are providing evidence of an association between Alzheimer’s disease and certain infectious agents, and may offer new opportunities for ground-breaking healthcare solutions. This handbook assembles and connects findings with regard to the infectious origin of Alzheimer’s disease, and the data presented in its chapters deserves the attention of the neuroscience community, physicians and the health departments of governments worldwide by virtue of its amount and quality. This handbook offers a comprehensive overview of the current knowledge regarding the topic of infection and Alzheimer’s disease, which could pinpoint the cause of this disease. Influential diagnosis, treatment and prevention strategies may also emerge from this crucial research area.

Author : Walter George Bradley
Publisher :
ISBN 13 : 9780750674690
Total Pages : 1672 pages
Book Rating : 4.95/5 ( download)

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Download or read book Neurology in Clinical Practice written by Walter George Bradley and published by . This book was released on 2004 with total page 1672 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

Author : Thimmaiah Govindaraju
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162740
Total Pages : 695 pages
Book Rating : 4.49/5 ( download)

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Download or read book Alzheimer's Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.

Author : Lawrence Broxmeyer, M.D.
Publisher :
ISBN 13 : 9781491287354
Total Pages : 190 pages
Book Rating : 4.57/5 ( download)

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Download or read book Alzheimer's Disease written by Lawrence Broxmeyer, M.D. and published by . This book was released on 2016-08-03 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: View video book trailer: https://www.youtube.com/watch'v=T4IHhHhCCds KIRKUS REVIEWS: "The author is an internist and a medical researcher, and his double mastery of both the scientific minutiae and historical nuances of his subject matter is breathtaking. This is more than an account of a scientific debate-it's also an examination of the sometimes-unempirical way that such debate proceeds, as it's conducted by human beings with agendas of their own. Although it's a relatively short book-less than 200 pages of text-it is by no means a quick read. Nevertheless, readers with strong sciencebackgrounds will be impressed by the author's undeniable competence, as well as his journalistic approach to chartering the evolution of thought regarding one of our era's most challenging diseases." Every seventy-two seconds someone in America develops Alzheimer's disease (AD). And it has been said that almost everyone living long enough will eventually show evidence of Alzheimer's disease. Thus far its cause has remained elusive. Nevertheless, recently, study after study, in which scientists have injected human Alzheimer diseased brain tissue into mice and other laboratory animals that later developed the disease have left little doubt that Alzheimer's arises from an infectious process-the focus of debate seeming to be which particular disease. And clearly, whatever the infectious cause behind Alzheimer's is, it must be a disease that is not only statistically widespread in the world today, but that was also prevalent at the time of Dr. Alzheimer. To be sure, it was German neuropathologist Oskar Fischer of the Prague school of neuropathology, Alzheimer's great rival, who was the first to suggest that infection might be causative for Alzheimer's. Fischer's credentials: he was the co-discoverer of Alzheimer's disease and tirelessly did autopsies on the brains of patients with Alzheimer's. Fischer's infectious view never gained immediate popularity, although today, more than a century later, a volume of data supporting such an approach has begun to accumulate. But was Fischer's specific microbe on the right track to discovering the cause of Alzheimer's to begin with? The evidence uncovered in this book seems to suggest that he was considerably closer than anyone else-either then or since. Now, internal medicine doctor and researcher Lawrence Broxmeyer, MD, takes readers on a journey back to the time of Dr. Alzheimer and his peers. Well-researched and documented, this important work explores a plausible, but overlooked, hypothesis about the etiology of this debilitating and widespread condition-and brings new information to the discussion about how to prevent a disease affecting millions of Americans today. So let us review that evidence.

Author : Deng-Feng Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2889715434
Total Pages : 153 pages
Book Rating : 4.35/5 ( download)

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Download or read book Infection, Inflammation, Cardiovascular diseases and Neurodegeneration written by Deng-Feng Zhang and published by Frontiers Media SA. This book was released on 2021-10-25 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Carolyn Merchant JD
Publisher : AuthorHouse
ISBN 13 : 1546259791
Total Pages : 623 pages
Book Rating : 4.94/5 ( download)

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Download or read book The Origin of Disease written by Carolyn Merchant JD and published by AuthorHouse. This book was released on 2018-10-12 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: US REVIEW OF BOOKS, Michael Radon theusreview.com/reviews/The-Origin-of-Disease-by-Carolyn-Merchant-JD-and-Christopher-Merchant-MD.html#.XLBmAehKi5o Containing exciting information and thought, this book could help people find ways to improve or avoid diseases that can dramatically alter lives. This book challenges a lot of accepted thinking in Western medicine, but all truly impactful ideas have to shatter the old to move [thought] forward. [T]he authors identify a pattern of the root causes of chronic illnesses and what can be done to fight maladies that many medical professionals say just happen and have to be lived with. For many people, medical books can be a hard hurdle to jump, but this book is written in an accessible style and format, and contains information useful to the layperson, not just medical professionals. PACIFIC BOOK REVIEW. Anthony Avina pacificbookreview.com/the-origin-of-disease-the-war-within This book does a great job of creating a conversation. It is a detailed, knowledgeable and thorough book filled with fascinating theories that all readers should have the opportunity to explore themselves. This is definitely an interesting book that will fascinate patients suffering from illnesses as well as doctors seeking new answers or medical researchers alike. It is a new perspective that is interesting to see, as the authors relay the causes of various chronic illnesses. The authors command over the medical expertise is both technical and yet relayed easily enough for patients and doctors alike to understand. If you enjoy medical books, suffer from an ailment or are curious about health overall, then you’ll want to grab your copy of The Origin of Disease: The War Within, Today! www.facebook.com/carolyn.merchant/39 www.theoriginofdiseases.com

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.51/5 ( download)

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Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Author : Louis Dvonch
Publisher : iUniverse
ISBN 13 : 0595262201
Total Pages : 418 pages
Book Rating : 4.05/5 ( download)

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Download or read book The Heart Attack Germ written by Louis Dvonch and published by iUniverse. This book was released on 2003-02-07 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perhaps you've read about the Heart Attack Germ in Reader's Digest. Or you may have seen the story about it on Dateline NBC. But The Heart Attack Germ is the first and only book that reveals the full story behind this astonishing and revolutionary medical breakthrough. A germ named Chlamydia pneumoniae has been identified by medical researchers the world over as the Heart Attack Germ. People infected by this germ are at a significantly increased risk for stroke, heart attack and other cardiovascular problems, including the symptoms of Alzheimer's disease. Several other common bacteria and viruses have also been associated with an increased risk of stroke and heart attack. All of these germs are contagious and easily transmitted from person to person. In fact, the odds are that you've already been infected by one or more of the germs of cardiovascular disease. The discovery of the Heart Attack Germ has produced improved treatments that, for the first time, attack the underlying cause of cardiovascular trouble. Vividly written and illustrated, The Heart Attack Germ will show you how to dramatically reduce your risk of stroke, heart attack and the symptoms of Alzheimer's: safely, painlessly, inexpensively and without surgery.