Adverse Effects Of Engineered Nanomaterials

Author : Bengt Fadeel
Publisher : Academic Press
ISBN 13 : 0128094907
Total Pages : 486 pages
Book Rating : 4.07/5 ( download)

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Download or read book Adverse Effects of Engineered Nanomaterials written by Bengt Fadeel and published by Academic Press. This book was released on 2017-02-14 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population. Uses a schematic, non-exhaustive approach to summarizes the most important research data in this field Discusses the health implications of experimental data in nanotoxicology Presents a completely revised edition that focuses on the human health impacts of engineered nanomaterials, including many organ-specific chapters

Author : Bengt Fadeel
Publisher : Academic Press
ISBN 13 : 0123869404
Total Pages : 367 pages
Book Rating : 4.01/5 ( download)

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Download or read book Adverse Effects of Engineered Nanomaterials written by Bengt Fadeel and published by Academic Press. This book was released on 2012-01-27 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety.

Author : Ashok K Singh
Publisher : Academic Press
ISBN 13 : 012801492X
Total Pages : 554 pages
Book Rating : 4.29/5 ( download)

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Download or read book Engineered Nanoparticles written by Ashok K Singh and published by Academic Press. This book was released on 2015-11-24 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM. The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health. It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects. Provides state-of-the-art physicochemical descriptions and methodologies for the characterization of engineered nanomaterials (ENM) Describes the potential toxicological effects of ENM and the nanotoxicological mechanisms of action Presents how to apply theory to practice in a public health and risk assessment setting

Author : Marina Dobrovolskaia
Publisher : World Scientific
ISBN 13 : 9814390259
Total Pages : 721 pages
Book Rating : 4.55/5 ( download)

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Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Marina Dobrovolskaia and published by World Scientific. This book was released on 2013 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Author : Jamie R. Lead
Publisher : Springer Nature
ISBN 13 : 3030798089
Total Pages : 263 pages
Book Rating : 4.86/5 ( download)

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Download or read book Nanotoxicology in Humans and the Environment written by Jamie R. Lead and published by Springer Nature. This book was released on 2021-12-13 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the area of ‘Nanotoxicology’ but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely.

Author : Alexandra Maertens
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164409
Total Pages : 307 pages
Book Rating : 4.08/5 ( download)

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Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.

Author : Chaudhery Mustansar Hussain
Publisher : John Wiley & Sons
ISBN 13 : 1119592968
Total Pages : 580 pages
Book Rating : 4.69/5 ( download)

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Download or read book The ELSI Handbook of Nanotechnology written by Chaudhery Mustansar Hussain and published by John Wiley & Sons. This book was released on 2020-03-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309253314
Total Pages : 230 pages
Book Rating : 4.14/5 ( download)

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Download or read book A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials written by National Research Council and published by National Academies Press. This book was released on 2012-05-09 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanotechnology sector, which generated about $225 billion in product sales in 2009, is predicted to expand rapidly over the next decade with the development of new technologies that have new capabilities. The increasing production and use of engineered nanomaterials (ENMs) may lead to greater exposures of workers, consumers, and the environment, and the unique scale-specific and novel properties of the materials raise questions about their potential effects on human health and the environment. Over the last decade, government agencies, academic institutions, industry, and others have conducted many assessments of the environmental, health, and safety (EHS) aspects of nanotechnology. The results of those efforts have helped to direct research on the EHS aspects of ENMs. However, despite the progress in assessing research needs and despite the research that has been funded and conducted, developers, regulators, and consumers of nanotechnology-enabled products remain uncertain about the types and quantities of nanomaterials in commerce or in development, their possible applications, and their associated risks. A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials presents a strategic approach for developing the science and research infrastructure needed to address uncertainties regarding the potential EHS risks of ENMs. The report summarizes the current state of the science and high-priority data gaps on the potential EHS risks posed by ENMs and describes the fundamental tools and approaches needed to pursue an EHS risk research strategy. The report also presents a proposed research agenda, short-term and long-term research priorities, and estimates of needed resources and concludes by focusing on implementation of the research strategy and evaluation of its progress, elements that the committee considered integral to its charge.

Author : Igor Linkov
Publisher : Springer Science & Business Media
ISBN 13 : 1402094914
Total Pages : 459 pages
Book Rating : 4.10/5 ( download)

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Download or read book Nanomaterials written by Igor Linkov and published by Springer Science & Business Media. This book was released on 2008-12-26 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential questions regarding the risks associated with the development and use of wide-ranging technologies enabled through engineered nanomaterials. For example, with over 600 consumer products available globally, what information exists that describes their risk to human health and the environment? What en- neering or use controls can be deployed to minimize the potential environmental health and safety impacts of nanomaterials throughout the manufacturing and product lifecycles? How can the potential environmental and health benefits of nanotechnology be realized and maximized? The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – started with building a foundation to harmonize risks and benefits associated with nanomaterials to develop risk management approaches and policies. More than 70 experts, from 19 countries, in the fields of risk assessment, decision-analysis, and security discussed the current state-of-knowledge with regard to nanomaterial risk and benefits. The discussion focused on the adequacy of available risk assessment tools to guide nanomaterial applications in industry and risk governance. The workshop had five primary purposes: Describe the potential benefits of nanotechnology enabled commercial products. Identify and describe what is known about environmental and human health risks of nanomaterials and approaches to assess their safety. Assess the suitability of multicriteria decision analysis for reconciling the benefits and risks of nanotechnology.

Author : Saura C. Sahu
Publisher : John Wiley & Sons
ISBN 13 : 1119896223
Total Pages : 453 pages
Book Rating : 4.27/5 ( download)

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Download or read book Impact of Engineered Nanomaterials in Genomics and Epigenomics written by Saura C. Sahu and published by John Wiley & Sons. This book was released on 2023-08-14 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impact of Engineered Nanomaterials in Genomics and Epigenomics Overview of current research and technologies in nanomaterial science as applied to omics science at the single cell level Impact of Engineered Nanomaterials in Genomics and Epigenomics is a comprehensive and authoritative compilation of the genetic processes and instructions that specifically direct individual genes to turn on or off, focusing on the developing technologies of engineering nanomaterials and their role in cell engineering which have become important research tools for pharmaceutical, biological, medical, and toxicological studies. Combining state-of-the art information on the impact of engineered nanomaterials in genomics and epigenomics, from a range of internationally recognized investigators from around the world, this edited volume offers unique insights into the current trends and future directions of research in this scientific field. Impact of Engineered Nanomaterials in Genomics and Epigenomics includes detailed information on sample topics such as: Impact of engineered nanomaterials in genomics and epigenomics, including adverse impact on glucose energy metabolism Toxicogenomics, toxicoepigenomics, genotoxicity and epigenotoxicity, and mechanisms of toxicogenomics and toxicoepigenomics Adverse effects of engineered nanomaterials on human environment and metabolomics pathways leading to ecological toxicity Meta-analysis methods to identify genomic toxicity mechanisms of engineered nanomaterials and biological effects of engineered nanomaterial exposure Artificial intelligence and machine learning of single-cell transcriptomics of engineered nanoparticles and trends in plant nano-interaction to mitigate abiotic stresses This comprehensive work is a valuable and excellent source of authoritative and up-to-date information for advanced students and researchers, toxicologists, the drug industry, risk assessors and regulators in academia, industry, and government, as well as for clinical scientists working in hospital and clinical environments.