Update On Polymers For Ocular Drug Delivery

Author : Atish S Mundada
Publisher : Smithers Rapra
ISBN 13 : 1847355641
Total Pages : 210 pages
Book Rating : 4.45/5 ( download)

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Download or read book Update on Polymers for Ocular Drug Delivery written by Atish S Mundada and published by Smithers Rapra. This book was released on 2011-12-20 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the instilled dose is ocularly absorbed. The effective dose of medication administered ophthalmically may be altered by increasing the retention time of medication in contact with the surface of the eye. To date, Pharmaceutical Technologists have tried to develop different novel formulations like gel, ocular inserts, collagen shields, implants, liposomes, nanoparticles, penetration enhancers and in-situ gelling systems, in order to increase the bioavailability and duration of the therapeutic action of ocular drugs and polymers plays an important role in all these approaches. This book provides detailed information regarding all such polymers which have been used and shown to be excellent in improving the bioavailability of ocular drugs.

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.81/5 ( download)

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Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Author : Andrea Haesslein
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.37/5 ( download)

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Download or read book Development of Ocular Drug Delivery Systems Using Biodegradable Polymers written by Andrea Haesslein and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Nigel M. Davies
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.27/5 ( download)

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Download or read book Mucoadhesive Polymers in Ocular Drug Delivery written by Nigel M. Davies and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher : Academic Press
ISBN 13 : 0128179104
Total Pages : 810 pages
Book Rating : 4.09/5 ( download)

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Download or read book Basic Fundamentals of Drug Delivery written by and published by Academic Press. This book was released on 2018-11-30 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.28/5 ( download)

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Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Author : Ashim K. Mitra
Publisher : Bentham Science Publishers
ISBN 13 : 1608051757
Total Pages : 301 pages
Book Rating : 4.55/5 ( download)

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Download or read book Treatise on Ocular Drug Delivery written by Ashim K. Mitra and published by Bentham Science Publishers. This book was released on 2013-06-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Author : Deepak Thassu
Publisher : CRC Press
ISBN 13 : 1439848017
Total Pages : 461 pages
Book Rating : 4.12/5 ( download)

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Download or read book Ocular Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2012-10-02 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Ba

Author : Richard T. Addo
Publisher : Springer
ISBN 13 : 3319476912
Total Pages : 185 pages
Book Rating : 4.19/5 ( download)

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Download or read book Ocular Drug Delivery: Advances, Challenges and Applications written by Richard T. Addo and published by Springer. This book was released on 2016-11-16 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Author : M.F. Saettone
Publisher : Springer Science & Business Media
ISBN 13 : 1475741758
Total Pages : 193 pages
Book Rating : 4.59/5 ( download)

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Download or read book Ophthalmic Drug Delivery written by M.F. Saettone and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the International Symposium on Ophthalmie Drug Delivery, which was held in Pisa in October 1986. Topical ophthalmic therapy is a matter of interest to specialists from different fields (medical, pharmaceutical, chemical, technological, etc.), who, unfortunately, have a tendency to meet separately, thus limiting a diffusion of knowledge, ideas and experience that would greatly favour the overall pro gress in this area of research. The Symposium, for the first time in Europe, provided the opportunity for specialists from different disciplines and from different countfies to meet, to discuss and to share their experience. This multidisciplinary approach is reflected in the wide variety of topics that appear in the book. The papers are aimed at reviewing many of the complex, interrelated, medical pharmaceutical and technological facets of topical ophthalmic therapy. lt is our hope that they may stimulate further thought in this fascinating field, and may provide possible guidelines for future research. The editors wish to express their appreciation to the sponsors of the Symposium: Fidia Research Laboratories, whose generosity permitted the meeting tobe held, and the ltalian National Research Council (CNR, Progetto Finalizzato Chimica Fine e Secondaria) who gave its scientific tutorship. Thanks are also due to the other Symposium contributors, ACRAF SpA, Rome, and Allergan Italia SpA, Rome. The assistance, support and coopera tion given before, during and after the Symposium by Dr. Patrizia Chetoni, Dr. Maria Tilde Torracca and Dr. Elena Parolini arealso gratefully acknowledged.