Tryptophan Metabolism Implications For Biological Processes Health And Disease

Author : Atilla Engin
Publisher : Humana Press
ISBN 13 : 3319156306
Total Pages : 385 pages
Book Rating : 4.09/5 ( download)

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Download or read book Tryptophan Metabolism: Implications for Biological Processes, Health and Disease written by Atilla Engin and published by Humana Press. This book was released on 2015-04-28 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacterial tryptophan biosynthesis and novel antimicrobials. Tryptophan Metabolism: Implications for Biological Processes, Health and Disease presents fundamental information on tryptophan related metabolic pathways and metabolites, implications of these products for specific biological processes, diseases and conditions. This book focuses on effects of tryptophan metabolites on human health and will appeal to researchers, clinicians and students within this field.

Author : Graziella Allegri
Publisher : Springer Science & Business Media
ISBN 13 : 1461501350
Total Pages : 736 pages
Book Rating : 4.50/5 ( download)

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Download or read book Developments in Tryptophan and Serotonin Metabolism written by Graziella Allegri and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the Tenth International Meeting of the International Study Group for Tryptophan Research (ISTR V), held at the University of Padova, Padova, Italy, from 25-29 June, 2002 under the auspices of the Ministry of Education, University and Research (MIUR) in Roma, the University of Padova, the Italian Chemical Society - Division of Pharmaceutical Chemistry, the Veneto Region and the City of Padova. The meeting was organized to cover the recent developments in the field of tryptophan research. Weare very honoured that so many speakers accepted our invitation to give plenary lectures which, with the other communications, demonstrated the high scientific value of the Meeting. The publications in this volume are subdivided into nine main chapters, and cover all the major aspects in immunology, neurobiology, psychiatry, pathology, clinics, metabolism, enzymology, pharmacology, toxicology, melatonin, exercise and analytical chemistry. The volume includes the contributions of 325 scientists from 24 countries, and the Musajo Memorial Lecture delivered by Prof. Osamu Hayaishi during the Opening Ceremony.

Author : Bruce Spiegelman
Publisher : Springer
ISBN 13 : 3319727907
Total Pages : 108 pages
Book Rating : 4.05/5 ( download)

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Download or read book Hormones, Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Author : Gerald Huether
Publisher : Springer Science & Business Media
ISBN 13 : 9780306462047
Total Pages : 880 pages
Book Rating : 4.44/5 ( download)

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Download or read book Tryptophan, Serotonin, and Melatonin written by Gerald Huether and published by Springer Science & Business Media. This book was released on 1999-10-31 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the Ninth Meeting of the "International Study Group for Tryptophan Research" (lSTRY), held at the University of Hamburg, Germany, from October 10 to 14, 1998. At this meeting the recent developments in the field of tryptophan research were presented by leading researchers from all over the world in 81 oral and 48 poster contri butions. Research on tryptophan and its derivatives provides an inexhaustible subject. At the conference we tried to compose a multifacetted picture of the recent investiga tions through contributions from the major disciplines involved. Thus, we tried to strike a balance between basic research topics and clinical, nutritional or industrial applica tions. We offered workshops on tryptophan (in sleep and mood), melatonjn, IDO-acti vation and the eosinophilia-myalgia syndrome (EMS) as a platform for intensive discussion for the participants. In these proceedings many contributions are multidisciplinary and have practical or theoretical implications for different research fields. Hence, we have organized this volume in nine main chapters according to basic disciplines and subjects. We are aware that this classification is artificial, but we hope that it is the best compromise for contributors and readers.

Author : Robert Schwarcz
Publisher : Springer
ISBN 13 : 9781468459548
Total Pages : 0 pages
Book Rating : 4.46/5 ( download)

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Download or read book Kynurenine and Serotonin Pathways written by Robert Schwarcz and published by Springer. This book was released on 2012-07-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Study Group for Tryptophan Research: Sixth International Meeting, held in Baltimore, Maryland, May 9--12, 1989

Author : Sandeep Mittal
Publisher : Springer
ISBN 13 : 9783319363219
Total Pages : 430 pages
Book Rating : 4.12/5 ( download)

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Download or read book Targeting the Broadly Pathogenic Kynurenine Pathway written by Sandeep Mittal and published by Springer. This book was released on 2016-08-23 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism. The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.

Author : Robert Schwarcz
Publisher : Springer Science & Business Media
ISBN 13 : 146845952X
Total Pages : 690 pages
Book Rating : 4.24/5 ( download)

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Download or read book Kynurenine and Serotonin Pathways written by Robert Schwarcz and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Study Group for Tryptophan Research: Sixth International Meeting, held in Baltimore, Maryland, May 9--12, 1989

Author : Martin Kohlmeier
Publisher : Elsevier
ISBN 13 : 0080537898
Total Pages : 841 pages
Book Rating : 4.94/5 ( download)

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Download or read book Nutrient Metabolism written by Martin Kohlmeier and published by Elsevier. This book was released on 2003-10-01 with total page 841 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.68/5 ( download)

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Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Author : Laura A. Sordillo
Publisher : Academic Press
ISBN 13 : 0128227915
Total Pages : 222 pages
Book Rating : 4.16/5 ( download)

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Download or read book Biophotonics, Tryptophan and Disease written by Laura A. Sordillo and published by Academic Press. This book was released on 2021-10-09 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophotonics, Tryptophan and Disease is a comprehensive resource on the key role of tryptophan in wide range of diseases as seen by using optics techniques. It explores the use of fluorescence spectroscopy, Raman, imaging techniques and time-resolved spectroscopy in normal and diseased tissues and shows the reader how light techniques (i.e. spectroscopy and imaging) can be used to detect, distinguish and evaluate diseases. Diseases covered include cancer, neurodegenerative diseases and other age-related diseases. Biophotonics, Tryptophan and Disease offers a clear presentation of techniques and integrates material from different disciplines into one resource. It is a valuable reference for students and interdisciplinary researchers working on the interface between biochemistry and molecular biology, translational medicine, and biophotonics. Shows the key role of tryptophan in diseases Emphasizes how optical techniques can be potent means of assessing many diseases Points to new ways of understanding autism, aging, depression, cancer and neurodegenerative diseases