Translational Neuroimaging

Author : Robert A. McArthur
Publisher : Academic Press
ISBN 13 : 0123869455
Total Pages : 464 pages
Book Rating : 4.56/5 ( download)

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Download or read book Translational Neuroimaging written by Robert A. McArthur and published by Academic Press. This book was released on 2012-10-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders.

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0128025964
Total Pages : 776 pages
Book Rating : 4.63/5 ( download)

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Download or read book Conn's Translational Neuroscience written by P. Michael Conn and published by Academic Press. This book was released on 2016-09-28 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

Author : Robert A. McArthur
Publisher : Academic Press
ISBN 13 : 0123869978
Total Pages : 463 pages
Book Rating : 4.75/5 ( download)

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Download or read book Translational Neuroimaging written by Robert A. McArthur and published by Academic Press. This book was released on 2012-10-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders Critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers Identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders

Author : Drozdstoy Stoyanov
Publisher : Frontiers Media SA
ISBN 13 : 2889639541
Total Pages : 175 pages
Book Rating : 4.40/5 ( download)

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Download or read book Progress in Translational Neuroimaging: Integrating Pathways, Systems and Phenomenology in Neurology and Psychiatry written by Drozdstoy Stoyanov and published by Frontiers Media SA. This book was released on 2020-08-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 412 pages
Book Rating : 4.79/5 ( download)

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Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Georgios P. D. Argyropoulos
Publisher : Springer Nature
ISBN 13 : 3030356876
Total Pages : 300 pages
Book Rating : 4.73/5 ( download)

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Download or read book Translational Neuroscience of Speech and Language Disorders written by Georgios P. D. Argyropoulos and published by Springer Nature. This book was released on 2020-02-27 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative brain abnormalities on speech and language. To this end, this edited volume brings together contributions from several leading experts in a markedly broad range of disciplines, comprising Neurology, Neurosurgery, Genetics, Engineering, Neuroimaging and Neurostimulation, Neuropsychology, and Speech and Language Therapy.

Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 458 pages
Book Rating : 4.05/5 ( download)

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Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Author : Trevor W. Robbins
Publisher : Springer
ISBN 13 : 3319339133
Total Pages : 503 pages
Book Rating : 4.39/5 ( download)

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Download or read book Translational Neuropsychopharmacology written by Trevor W. Robbins and published by Springer. This book was released on 2016-09-22 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.

Author : Sergiu Groppa
Publisher : Humana
ISBN 13 : 9781071612125
Total Pages : 335 pages
Book Rating : 4.23/5 ( download)

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Download or read book Translational Methods for Multiple Sclerosis Research written by Sergiu Groppa and published by Humana. This book was released on 2021-08-03 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

Author : Lori A. Whitten
Publisher : RTI Press
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4./5 ( download)

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Download or read book Functional magnetic resonance imaging (fMRI) written by Lori A. Whitten and published by RTI Press. This book was released on 2012-12-11 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sophisticated methods of neuroscience—including molecular genetics, structural and functional neuroimaging, animal models, and experimental tasks that approximate real-world behaviors in human research—have yielded important insights about typical functioning and neurobehavioral disorders. Translational neuroscience endeavors to use this knowledge to improve the human condition by developing and improving interventions for these disorders. This paper reviews the literature on the contribution of functional magnetic resonance imaging (fMRI) and two related techniques, resting-state fMRI (rs-fMRI) and real-time fMRI (rt-fMRI), to the diagnosis and treatment of behavioral problems and psychiatric disorders. It also explains how incorporating neuroscience principles and techniques into research on the prevention of substance misuse and antisocial behavior may spur advances and innovations in this important area. This article argues that fMRI’s potential contribution to these prevention efforts has yet to be fully realized, explores new ways in which the technique could be adapted to that end, highlights some of the work by researchers in the vanguard of this effort, and notes limitations of fMRI and ethical concerns the technique raises.