Translational Anatomy And Cell Biology Of Autism Spectrum Disorder

Author : Michael J. Schmeisser
Publisher : Springer
ISBN 13 : 3319524984
Total Pages : 211 pages
Book Rating : 4.86/5 ( download)

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Download or read book Translational Anatomy and Cell Biology of Autism Spectrum Disorder written by Michael J. Schmeisser and published by Springer. This book was released on 2017-05-25 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field including several members of the EU-AIMS initiative launched by the European Union to develop novel treatments for ASD have contributed chapters on several topics covering all crucial aspects of translational ASD research with a special emphasis on ASD model systems including stem cells and animals. Primary objective is to clarify how anatomical and cell biological phenotypes of ASD will help to translate basic mechanisms to clinical practice and to efficiently treat affected individuals in the near future.

Author :
Publisher : Academic Press
ISBN 13 : 0128212438
Total Pages : 404 pages
Book Rating : 4.31/5 ( download)

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Download or read book Autism written by and published by Academic Press. This book was released on 2020-07-23 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism, Volume 173 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. Chapters in this new release include updates on atypical brain development in autism spectrum disorder, predicting early diagnosis of autism spectrum disorder using neural and behavioral measures, the roles of the endocannabinoid system in autism spectrum disorder, the neurobiology of sensory processing in autism spectrum disorder, the effects of oxytocin administration on individuals with ASD, resting-state abnormalities of posterior cingulate in autism spectrum disorder, and more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Author : Maria de los Angeles Robinson-Agramonte
Publisher : Springer
ISBN 13 : 3319163213
Total Pages : 218 pages
Book Rating : 4.15/5 ( download)

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Download or read book Translational Approaches to Autism Spectrum Disorder written by Maria de los Angeles Robinson-Agramonte and published by Springer. This book was released on 2015-06-10 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any, proven therapies for the majority of the disorders. Among the topic addressed are neural plasticity, neuroimmunology, neuroinflammation, neuroimaging, and appropriate animal and genetic models.

Author : Paul Spencer
Publisher : American Medical Publishers
ISBN 13 : 9781639279029
Total Pages : 0 pages
Book Rating : 4.24/5 ( download)

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Download or read book Translational and Clinical Research in Autism Spectrum Disorders written by Paul Spencer and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects how a person perceives and interacts with others, leading to problems in social interaction and communication. Limited and repetitive patterns of conduct are also part of the disorder. While autism is a lifelong disease, the extent to which these challenges limit a person's capacity to function varies from person to person. The term 'spectrum disorders' signifies the wide variety of symptoms and severity associated with autism. Genetic factors are primarily the reason for the disorder's occurrence. ASD appears early in childhood and is related to social, scholastic, and occupational challenges. Autism signs appear as early as the first year of life. Some of the complications linked with the disease include difficulties in school and successful learning, work issues, inability to live independently, social isolation, and family stress. This book is a collection of translational and clinical researches on autism. The readers would gain knowledge that would broaden their perspective about autism spectrum disorders.

Author : Anna Strunecka
Publisher :
ISBN 13 : 9781608053964
Total Pages : 234 pages
Book Rating : 4.62/5 ( download)

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Download or read book Cellular and Molecular Biology of Autism Spectrum Disorders written by Anna Strunecka and published by . This book was released on 2010-12 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades the incidence of autism spectrum disorders (ASD) has increased dramatically. The etiology of ASD remains an unsolved puzzle to scientists, physicians, pediatricians, psychiatrists, and pharmacologists. This book will address what is presently known concerning the pathophysiology of ASD from a cellular and molecular perspective. Our explanation is based on the interaction between repetitive systemic immune stimulation with concomitant chronic brain activation of microglia, which leads to overstimulation of glutamate receptors and inflammatory cytokine receptors. The book will explain, for the first time, the effects of immunoexcitotoxicity on the brain development, neurophysiology, and pathology. This book will not only attempt to explain the finding in ASD, but will offer treatment proposals that address each of these mechanisms. It will also explain how previous, often successful treatment methods, may indeed operate through the immunoexcitotoxic mechanism.

Author : Detlev Boison
Publisher : Oxford University Press
ISBN 13 : 0199322295
Total Pages : 657 pages
Book Rating : 4.99/5 ( download)

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Download or read book Homeostatic Control of Brain Function written by Detlev Boison and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Author : S.H. Fatemi
Publisher : Springer Science & Business Media
ISBN 13 : 0387767614
Total Pages : 473 pages
Book Rating : 4.11/5 ( download)

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Download or read book Reelin Glycoprotein written by S.H. Fatemi and published by Springer Science & Business Media. This book was released on 2008-06-04 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reelin glycoprotein is a serine protease with important roles in embryogenesis and during adult life. This comprehensive and integrative book examines the role that reelin plays in the etiology of various neuropsychiatric disorders, including schizophrenia and autism. The book provides an unprecedented analysis of this emerging and novel protein by examining evidence from genetic, neuroanatomic, biochemical, and behavioral studies.

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.45/5 ( download)

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Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author :
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.21/5 ( download)

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Download or read book Diagnostic History and Treatment of School-aged Children with Autism Spectrum Disorder and Special Health Care Needs written by and published by . This book was released on 2012 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Joseph I. Tracy
Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.43/5 ( download)

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Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.