Thermodynamics, Kinetics and Landscapes in Alpha-lytic Protease

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Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.27/5 ( download)

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Book Synopsis Thermodynamics, Kinetics and Landscapes in Alpha-lytic Protease by : Sheila Jaswal

Download or read book Thermodynamics, Kinetics and Landscapes in Alpha-lytic Protease written by Sheila Jaswal and published by . This book was released on 2000 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Decoupled Folding and Functional Landscapes Allow Alpha-lytic Protease and Streptomyces Griseus Protease B to Develop Novel Native-state Properties

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ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.85/5 ( download)

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Book Synopsis Decoupled Folding and Functional Landscapes Allow Alpha-lytic Protease and Streptomyces Griseus Protease B to Develop Novel Native-state Properties by : Stephanie Marie Truhlar

Download or read book Decoupled Folding and Functional Landscapes Allow Alpha-lytic Protease and Streptomyces Griseus Protease B to Develop Novel Native-state Properties written by Stephanie Marie Truhlar and published by . This book was released on 2004 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Folding

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Publisher : Nova Publishers
ISBN 13 : 9781594548352
Total Pages : 294 pages
Book Rating : 4.58/5 ( download)

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Book Synopsis Protein Folding by : Tony R. Obalinsky

Download or read book Protein Folding written by Tony R. Obalinsky and published by Nova Publishers. This book was released on 2006 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are one of the most basic components of all living cells and therefore serve a vital purpose in the cells of animals, plants and bacteria. They are comprised of chains of amino acids, which are held together by ribosome. These chains have many different patterns, which are known as `folds.' These folds are complicated, and therefore susceptible to irregularities that are known to be the source of many diseases. Cystic fibrosis, mad cow disease, Alzheimer's disease, emphysema and others are all initiated by improper protein folds. It is clear that, improving our understanding of protein folding is a key to fighting these diseases. This book presents recently performed research from around the world on this important subject.

Introduction to Proteins

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Publisher : CRC Press
ISBN 13 : 1498747213
Total Pages : 1489 pages
Book Rating : 4.19/5 ( download)

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Book Synopsis Introduction to Proteins by : Amit Kessel

Download or read book Introduction to Proteins written by Amit Kessel and published by CRC Press. This book was released on 2018-03-22 with total page 1489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website: http://ibis.tau.ac.il/wiki/nir_bental/index.php/Introduction_to_Proteins_Book. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012

Protein Homeostasis Diseases

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Publisher : Academic Press
ISBN 13 : 0128191333
Total Pages : 450 pages
Book Rating : 4.30/5 ( download)

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Book Synopsis Protein Homeostasis Diseases by : Angel L. Pey

Download or read book Protein Homeostasis Diseases written by Angel L. Pey and published by Academic Press. This book was released on 2020-02-13 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders. Provides an interdisciplinary examination of protein homeostasis disorders, with an emphasis on treatment strategies employing small natural and pharmacological ligands Offers applied approaches in employing high throughput sequencing and screening to develop pharmacological chaperones to treat protein homeostasis disease Gathers expertise from a range of international chapter authors who work across various biological methods and disease specific disciplines of relevance

Function and Destruction of Protein Folding Catalysts

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ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.50/5 ( download)

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Book Synopsis Function and Destruction of Protein Folding Catalysts by : Erin Lynn Cunningham

Download or read book Function and Destruction of Protein Folding Catalysts written by Erin Lynn Cunningham and published by . This book was released on 2003 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2452 pages
Book Rating : 4.3J/5 ( download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Advanced Techniques in Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 3540307869
Total Pages : 290 pages
Book Rating : 4.60/5 ( download)

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Book Synopsis Advanced Techniques in Biophysics by : José Luis R. Arrondo

Download or read book Advanced Techniques in Biophysics written by José Luis R. Arrondo and published by Springer Science & Business Media. This book was released on 2007-04-21 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

Handbook of Proteolytic Enzymes

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Publisher : Academic Press
ISBN 13 : 0123822203
Total Pages : 4097 pages
Book Rating : 4.08/5 ( download)

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Book Synopsis Handbook of Proteolytic Enzymes by : Alan J. Barrett

Download or read book Handbook of Proteolytic Enzymes written by Alan J. Barrett and published by Academic Press. This book was released on 2012-10-30 with total page 4097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. The only comprehensive book on proteolytic enzymes Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features Over 1000 peptidases included

Fundamentals of Neurodegeneration and Protein Misfolding Disorders

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Publisher : Springer
ISBN 13 : 3319221175
Total Pages : 378 pages
Book Rating : 4.75/5 ( download)

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Book Synopsis Fundamentals of Neurodegeneration and Protein Misfolding Disorders by : Martin Beckerman

Download or read book Fundamentals of Neurodegeneration and Protein Misfolding Disorders written by Martin Beckerman and published by Springer. This book was released on 2015-11-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on multiple fronts. These findings provide novel insights on how amyloidogenic oligomers and fibrils form, interconvert from one state to another, and propagate from cell to cell and region to region. Starting with protein folding and protein quality control basics, the reader will learn how misfolded proteins can cause diseases ranging from prion diseases to Alzheimer’s disease and Parkinson’s disease to Huntington’s disease, amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Authoritative but written in a clear and engaging style, Fundamentals of Neurodegeneration and Protein Misfolding Disorders addresses one of today’s forefront areas of science and medicine. The text emphasizes the new groundbreaking biophysical and biochemical methods that enable molecular-level explorations and the conceptual breakthroughs that result. It contains separate chapters on each of the major disease classes. Special emphasis is placed on those factors and themes that are common to the diseases, especially failures in synaptic transmission, mitochondrial control, and axonal transport; breakdowns in RNA processing; the potential role of environmental factors; and the confounding effects of neuroinflammation. The book is ideal for use in teaching at the advanced undergraduate and graduate levels, and serves as a comprehensive reference for a broad audience of students and researchers in neuroscience, molecular biology, biological physics and biomedical engineering.