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Author : Pradeep Chhaya
Publisher : Springer Nature
ISBN 13 : 9819943183
Total Pages : 562 pages
Book Rating : 4.80/5 ( download)
Download or read book The Topological Model of Genome and Evolution written by Pradeep Chhaya and published by Springer Nature. This book was released on with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raul Rabadan
Publisher : Cambridge University Press
ISBN 13 : 1107159547
Total Pages : 521 pages
Book Rating : 4.49/5 ( download)
Download or read book Topological Data Analysis for Genomics and Evolution written by Raul Rabadan and published by Cambridge University Press. This book was released on 2019-12-19 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to geometric and topological methods to analyze large scale biological data; includes statistics and genomic applications.
Author : Xun Gu
Publisher :
ISBN 13 :
Total Pages : 259 pages
Book Rating : 4.81/5 ( download)
Download or read book Statistical Theory and Methods for Evolutionary Genomics written by Xun Gu and published by . This book was released on 2011 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarising the statistical framework of evolutionary genomics, this text illustrates how statistical modelling and testing can enhance our understanding of functional genomic evolution.--[Source inconnue].
Author : Nataša Jonoska
Publisher : Springer Science & Business Media
ISBN 13 : 3642401937
Total Pages : 522 pages
Book Rating : 4.30/5 ( download)
Download or read book Discrete and Topological Models in Molecular Biology written by Nataša Jonoska and published by Springer Science & Business Media. This book was released on 2013-12-23 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.
Author : Gustavo Caetano-Anoll¿s
Publisher : John Wiley & Sons
ISBN 13 : 1118210719
Total Pages : 529 pages
Book Rating : 4.10/5 ( download)
Download or read book Evolutionary Genomics and Systems Biology written by Gustavo Caetano-Anoll¿s and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
Author : Cedric Chauve
Publisher : Springer
ISBN 13 : 9781447170167
Total Pages : 0 pages
Book Rating : 4.64/5 ( download)
Download or read book Models and Algorithms for Genome Evolution written by Cedric Chauve and published by Springer. This book was released on 2016-09-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.
Author : Giorgio Bernardi
Publisher : Elsevier
ISBN 13 : 0080461875
Total Pages : 459 pages
Book Rating : 4.78/5 ( download)
Download or read book Structural and Evolutionary Genomics written by Giorgio Bernardi and published by Elsevier. This book was released on 2005-12-19 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics. As the subtitle indicates the book discusses the fundamental importance of natural selection in shaping genomes. In terms of numbers, neutral and nearly neutral mutations represent most mutations, but a "regional" control is exerted by natural selection (essentially negative or purifying selection). A "neo-selectionist" model is proposed for genome evolution. · Summarizes the existing knowledge on genome organization and evolution in a self-contained book · Discusses important open problem, without refraining from criticism whenever appropriate
Author : Axel Meyer
Publisher : Springer Science & Business Media
ISBN 13 : 9401002630
Total Pages : 242 pages
Book Rating : 4.39/5 ( download)
Download or read book Genome Evolution written by Axel Meyer and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.
Author : Dan Graur
Publisher : Sinauer
ISBN 13 : 9781605354699
Total Pages : 0 pages
Book Rating : 4.94/5 ( download)
Download or read book Molecular and Genome Evolution written by Dan Graur and published by Sinauer. This book was released on 2015-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.
Author : Jotun Hein
Publisher : Oxford University Press, USA
ISBN 13 : 9780191546150
Total Pages : 298 pages
Book Rating : 4.51/5 ( download)
Download or read book Gene Genealogies, Variation and Evolution: A primer in coalescent theory written by Jotun Hein and published by Oxford University Press, USA. This book was released on 2004-12-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)
