The Spectrum Of Neuroendocrine Neoplasia

Author : Sylvia L. Asa
Publisher : Springer Nature
ISBN 13 : 3030543919
Total Pages : 478 pages
Book Rating : 4.14/5 ( download)

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Download or read book The Spectrum of Neuroendocrine Neoplasia written by Sylvia L. Asa and published by Springer Nature. This book was released on 2020-10-19 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrine neoplasms comprise a large family of proliferative lesions that involve almost every part of the body. Our understanding of their cells of origin as well as the pathology, pathophysiology and genetics of these neoplasms has made tremendous advances in the last few decades. While they are often discussed as separate entities in textbooks of gastroenteropancreatic pathology and pulmonary pathology, their scope is much broader. The book conveys the similarities and differences of these fascinating tumors that may be found from the hypothalamus and pituitary to the rectum, and in soft tissue as well as in many organs. Written by experts in the field, the authors emphasize their structural, functional, predictive and prognostic features and attempt to provide the clinical context that allows improved diagnosis and therapy while building on the genetics that clarifies patterns of inheritance and predisposition to tumor development through precursor lesions. The Spectrum of Neuroendocrine Neoplasia provides a broad overview of neuroendocrine neoplasms using a practical approach to diagnosis, histological classification and therapy, and presents the most important and significant developments of the technologies used to diagnose, classify and treat them.

Author : Giordano Beretta
Publisher : Springer Nature
ISBN 13 : 3030728307
Total Pages : 331 pages
Book Rating : 4.04/5 ( download)

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Download or read book Neuroendocrine Neoplasia Management written by Giordano Beretta and published by Springer Nature. This book was released on 2021-07-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease. The first part of the book focuses on the history, epidemiology and the most relevant scientific achievements, covering the discoveries in genetic and molecular biology, the endoscopic techniques with guided biopsy, and the metabolic imaging with hybrid PET/CT and MRI/CT. It particularly highlights the emerging strategies in therapy, surgery and mini-invasive surgery as well as loco-regional and systemic treatments, including targeted therapy and/or biological therapies. The second part then explores the management of NENs of various anatomical origins and/or with peculiar biology. It describes the range of the current options and the most relevant results from the clinical trials. This informative book provides valuable insights for all those interested in the management of neuroendocrine neoplasia.

Author : Sudha R. Kini
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 146982597X
Total Pages : 579 pages
Book Rating : 4.77/5 ( download)

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Download or read book Cytopathology of Neuroendocrine Neoplasia written by Sudha R. Kini and published by Lippincott Williams & Wilkins. This book was released on 2013-02-04 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neuroendocrine system is fascinating. It is an intriguing, complex system. For centuries, it has sustained the interest of scientists, who have provided the community with a wealth of information on neuroendocrine tumors types—history, genetics, clinical presentation, surgical pathology, differential diagnoses...on everything except cytopathology...until now. This one-of-a-kind color atlas fills a long-standing void in neuroendocrine resources. This atlas provides clear, descriptive information on the cytopathology of neuroendocrine tumor types and differential diagnoses in one cutting-edge, comprehensive resource. This unique atlas is dedicated exclusively to providing expert, illustrated coverage of the cytopathology of neuroendocrine tumors.

Author : M. Papotti
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318027731
Total Pages : 282 pages
Book Rating : 4.30/5 ( download)

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Download or read book Neuroendocrine Tumors: A Multidisciplinary Approach written by M. Papotti and published by Karger Medical and Scientific Publishers. This book was released on 2015-08-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term ‘carcinoid’ entered medical literature over 100 years ago to describe a peculiar intestinal epithelial neoplasm. Since then, a large body of literature has expanded the concept of carcinoid, later replaced by the term ‘NeuroEndocrine Tumor’ (NET), defining a wide spectrum of peculiar tumors, potentially affecting all organs and tissues, originating from neuroendocrine cells, sharing, but, at the same time, keeping, pathognomonic pathological, radiological and clinical features. This book provides an authoritative overview of the epidemiological, clinical, genetic, molecular and pathological characteristics of NETs and highlights the most relevant controversial issues in the classification, diagnosis and therapy. Furthermore the new frontiers in the field of medical therapies are presented, through a multidisciplinary and translational approach. Considering the fact that NETs have been recently demonstrated less rare as considered so far, 'Neuroendocrine Tumors: A Multidisciplinary Approach' is a must read for endocrinologists, gastroenterologists, endocrine surgeons, as well as pathologists, nuclear medicine physicians and radiologists focused on NET.

Author : Maria Rosaria Raspollini
Publisher : Cambridge University Press
ISBN 13 : 1107170451
Total Pages : 433 pages
Book Rating : 4.52/5 ( download)

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Download or read book Gynecologic and Urologic Pathology written by Maria Rosaria Raspollini and published by Cambridge University Press. This book was released on 2019-02-21 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.

Author : Ozgur Mete
Publisher : Cambridge University Press
ISBN 13 : 1107443318
Total Pages : 1091 pages
Book Rating : 4.10/5 ( download)

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Download or read book Endocrine Pathology with Online Resource written by Ozgur Mete and published by Cambridge University Press. This book was released on 2016-07-14 with total page 1091 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and critical review of the current clinical, radiologic, biochemical, molecular, cytogenetic, immunologic and histopathologic aspects of endocrine disorders.

Author : Joseph R. Pisegna
Publisher : Springer
ISBN 13 : 1493917986
Total Pages : 175 pages
Book Rating : 4.83/5 ( download)

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Download or read book Management of Pancreatic Neuroendocrine Tumors written by Joseph R. Pisegna and published by Springer. This book was released on 2014-10-15 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.

Author : International Agency for Research on Cancer
Publisher : World Health Organization
ISBN 13 : 9789283224365
Total Pages : 410 pages
Book Rating : 4.61/5 ( download)

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Download or read book Who Classification of Tumours of the Lung, Pleura, Thymus and Heart written by International Agency for Research on Cancer and published by World Health Organization. This book was released on 2015-03-16 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart is the seventh volume in the Fourth Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome.

Author : James C. Yao
Publisher : Springer Science & Business Media
ISBN 13 : 1603279970
Total Pages : 274 pages
Book Rating : 4.70/5 ( download)

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Download or read book Neuroendocrine Tumors written by James C. Yao and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management. In this volume, an outstanding group of the world’s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of all the major types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options.

Author : P. Nicolai
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318066702
Total Pages : 266 pages
Book Rating : 4.08/5 ( download)

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Download or read book Anterior Skull Base Tumors written by P. Nicolai and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.