The Science And Practice Of Lithium Therapy

Author : Gin S. Malhi
Publisher : Springer
ISBN 13 : 3319459236
Total Pages : 342 pages
Book Rating : 4.33/5 ( download)

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Download or read book The Science and Practice of Lithium Therapy written by Gin S. Malhi and published by Springer. This book was released on 2016-11-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.

Author : Walter A Brown
Publisher : National Geographic Books
ISBN 13 : 1631491997
Total Pages : 0 pages
Book Rating : 4.93/5 ( download)

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Download or read book Lithium written by Walter A Brown and published by National Geographic Books. This book was released on 2019-08-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable untold story of a miracle drug, the forgotten pioneer who discovered it, and the fight to bring lithium to the masses. The DNA double helix, penicillin, the X-ray, insulin—these are routinely cited as some of the most important medical discoveries of the twentieth century. And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization. From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented. With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again. Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

Author : F.N. Johnson
Publisher : Springer Science & Business Media
ISBN 13 : 9401171971
Total Pages : 464 pages
Book Rating : 4.77/5 ( download)

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Download or read book Handbook of Lithium Therapy written by F.N. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a medical student in the 1930s, I remember well that a very clear line of distinction was drawn between physical illness and mental illness. Physical illness resulted from pathology which could be identified and studied in detail and the cause could often be deduced. Treatment thus was often specific and based upon a proper appreciation of underlying basic science. Mental illness, on the other hand, could not, it was believed, be based upon identifiable changes in basic science. It was literally 'all in the mind' and, occurring in the absence of causes that could be identified, analysed and remedied, had no treatment that could in any way be called specific. N ow it is all too easy, in Medicine, for a doctor to become so immersed in a specialty that he fails to notice how his colleagues in other specialties are faring and, through laziness, to miss advances even of fundamental importance in fields other than those in which he himself works. As a consultant surgeon, after W orId War II, although I realized the importance of keeping in touch with those medical specialties which appeared to have a common interface with my own surgical interests, such as general medi cine, gastro-enterology, hepatology and endocrinology, it did not occur to me that there was any pressing need to ask what was new in Psychological Medicine.

Author : Aysegül Yildiz
Publisher : Oxford University Press, USA
ISBN 13 : 0199300534
Total Pages : 710 pages
Book Rating : 4.32/5 ( download)

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Download or read book The Bipolar Book written by Aysegül Yildiz and published by Oxford University Press, USA. This book was released on 2015 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bipolar Book covers not only clinical and pathophysiological matters, but also technical aspects of the evidence accumulation for treatment of bipolar disorder.

Author : Frederick Neil Johnson
Publisher : Springer
ISBN 13 : 1349072893
Total Pages : 229 pages
Book Rating : 4.97/5 ( download)

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Download or read book The History of Lithium Therapy written by Frederick Neil Johnson and published by Springer. This book was released on 1984-06-18 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Charles D. Ciccone
Publisher : F.A. Davis
ISBN 13 : 0803640048
Total Pages : 1217 pages
Book Rating : 4.47/5 ( download)

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Download or read book Davis's Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Author : Basant K. Puri
Publisher : OUP Oxford
ISBN 13 : 0191649279
Total Pages : 240 pages
Book Rating : 4.71/5 ( download)

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Download or read book Drugs in Psychiatry written by Basant K. Puri and published by OUP Oxford. This book was released on 2013-02-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Drugs in series, the updated second edition of this practical pocketbook summarizes essential information on all the major drugs currently used in clinical psychiatric practice. Beginning with a brief discussion on drugs in psychiatry, the text moves on to consider the principles of psychopharmacology, which form the foundation of the sound, scientifically based use of drugs in psychiatry. Details are then given, in turn, of the main non-depot antipsychotic drugs, antipsychotic depot injections, antimanic drugs, tricyclic and related antidepressant drugs, monoamine-oxidase inhibitors, selective serotonin re-uptake inhibitors, and other antidepressants. This practical pocketbook is an essential companion for all medical staff involved in psychopharmacology, both for learning and quick reference.

Author : Husseini K. Manji
Publisher : American Psychiatric Pub
ISBN 13 : 1585628239
Total Pages : 462 pages
Book Rating : 4.30/5 ( download)

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Download or read book Bipolar Medications written by Husseini K. Manji and published by American Psychiatric Pub. This book was released on 2008-11-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lithium, the treatment of choice for mania since its usefulness was first reported, has been shown to have varied effects on multiple biological systems, including electrolyte flux and neurochemistry. Recent advances in cellular and molecular biology promise to provide clinicians with a better understanding of the etiology of bipolar disorder and new options for treatment. Bipolar Medications: Mechanisms of Action presents the treatment and prophylaxis of bipolar disorder. More than 40 investigators share research and insight into the neurobiological mechanisms that help to explain the powerful effects of new antibipolar drugs. This comprehensive text Examines valproic acid, lamotrigine, inositol monophosphatase inhibitors, and protein kinase C inhibitors that have the potential to revolutionize clinical practice and provide new hypotheses on the etiology of bipolar disorder Presents the current understanding of the cellular mechanisms of action of mood-stabilizing agents Discusses the emergence of valproate as a powerful lithium alternative and examines the preliminary indications that lamotrigine will be an effective option Examines the issue of withdrawal rebound, which can make lithium ineffective or even counterproductive, and reviews inositol monophosphatase inhibitors that mimic lithium action in patients Compares lithium, carbamazepine, and valproate and their differential mechanisms, which could form the basis of a "rational polypharmacy" of manic depressive illness Examines behavioral models important in the screening of new antibipolar compounds and the effects of antibipolar compounds on immediate early genes Complete with extensive references, tables, and figures, this text is essential reading for any clinician who treats patients with bipolar disorder. It thoroughly documents the latest in psychopharmacology, as well as projecting future advances in the treatment of bipolar disorder.

Author : Seth Fletcher
Publisher : Hill and Wang
ISBN 13 : 1429922915
Total Pages : 272 pages
Book Rating : 4.13/5 ( download)

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Download or read book Bottled Lightning written by Seth Fletcher and published by Hill and Wang. This book was released on 2011-05-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lithium batteries may hold the key to an environmentally sustainable, oil-independent future. From electric cars to a "smart" power grid that can actually store electricity, letting us harness the powers of the sun and the wind and use them when we need them, lithium—a metal half as dense as water, found primarily in some of the most uninhabitable places on earth—has the potential to set us on a path toward a low-carbon energy economy. In Bottled Lightning, the science reporter Seth Fletcher takes us on a fascinating journey, from the salt flats of Bolivia to the labs of MIT and Stanford, from the turmoil at GM to cutting-edge lithium-ion battery start-ups, introducing us to the key players and ideas in an industry with the power to reshape the world. Lithium is the thread that ties together many key stories of our time: the environmental movement; the American auto industry, staking its revival on the electrification of cars and trucks; the struggle between first-world countries in need of natural resources and the impoverished countries where those resources are found; and the overwhelming popularity of the portable, Internet-connected gadgets that are changing the way we communicate. With nearly limitless possibilities, the promise of lithium offers new hope to a foundering American economy desperately searching for a green-tech boom to revive it.

Author : Nassir Ghaemi
Publisher : Oxford University Press, USA
ISBN 13 : 0199995486
Total Pages : 601 pages
Book Rating : 4.86/5 ( download)

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Download or read book Clinical Psychopharmacology written by Nassir Ghaemi and published by Oxford University Press, USA. This book was released on 2019-01-04 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.