The Science And Ethics Of Engineering The Human Germ Line

Author : Jon W. Gordon
Publisher : John Wiley & Sons
ISBN 13 : 0471478202
Total Pages : 304 pages
Book Rating : 4.01/5 ( download)

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Download or read book The Science and Ethics of Engineering the Human Germ Line written by Jon W. Gordon and published by John Wiley & Sons. This book was released on 2003-09-24 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: With implications that go to the core of what it means to be human, the issues raised by genetic manipulation-especially cloning-have sparked a passionate debate among governmental, religious, and scientific quarters, as well as the media and the general public. Keeping to the actual science rather than speculation is of the utmost importance for an enlightened approach to this weighty discussion. In clear, lively prose, The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze provides an authoritative treatment of the principles of science and bioethics that bear upon such technologies as germ-line insertion and cloning. It offers a realistic assessment of possible applications, limitations, and new developments likely to arise in these areas. Written by a top physician-investigator, this book progresses from the basics of building a living organism from inanimate parts through to recombinant DNA technology, assisted reproductive technologies, and gene transfer and germ-line engineering. Ethical considerations are woven into this material throughout, while a special section covers the intellectual role played by various social biases. As genetic and reproductive technologies spread from the laboratory to the clinic-and society takes further notice-students and practitioners of biology and medicine, as well as the interested general reader, will find The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze to be an essential and accessible guide to these important subjects.

Author : Gregory Stock
Publisher : Oxford University Press
ISBN 13 : 0195350936
Total Pages : 186 pages
Book Rating : 4.37/5 ( download)

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Download or read book Engineering the Human Germline written by Gregory Stock and published by Oxford University Press. This book was released on 2000-02-03 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section of short essays on the implications of our technological ability. Also included is a panel discussion in which leading scientists, ethicists, and public policy workers give voice to their thoughts and concerns regarding our impending genetic technologies. Many world leaders in these fields, including Leroy Hood, French Anderson, Mario Capecchi, Daniel Koshland, Michael Rose, Lee Silver, and James Watson, have contributed to this volume, providing the essential elements of the debate over germline engineering. If you have ever pondered the question: "Would I be willing to genetically alter my own child-to-be, given a safe, reliable technology, offering a tempting possibility?", this book will be an indispensable guide.

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452880
Total Pages : 329 pages
Book Rating : 4.85/5 ( download)

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Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Author : The Royal Society
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.32/5 ( download)

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Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Author : Henry T. Greely
Publisher : MIT Press
ISBN 13 : 0262543885
Total Pages : 395 pages
Book Rating : 4.80/5 ( download)

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Download or read book CRISPR People written by Henry T. Greely and published by MIT Press. This book was released on 2022-03-01 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.

Author : Ruth Hubbard
Publisher : Beacon Press
ISBN 13 : 9780807004319
Total Pages : 260 pages
Book Rating : 4.16/5 ( download)

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Download or read book Exploding the Gene Myth written by Ruth Hubbard and published by Beacon Press. This book was released on 1999-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Genetic Information Is Produced and Manipulated by Scientists, Physicians, Employers, Insurance Companies, Educators, and Law Enforcers

Author : Emmanuel Agius
Publisher : Springer Science & Business Media
ISBN 13 : 9401151490
Total Pages : 180 pages
Book Rating : 4.98/5 ( download)

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Download or read book Germ-Line Intervention and Our Responsibilities to Future Generations written by Emmanuel Agius and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contemporary ethical discussion widespread concern about the potential risks of genetic engineering is raising new and fundamental questions about our responsibilities towards unborn generations. Newly acquired knowledge in genetic engineering techniques has brought about not only potential benefits but also immense risks for the well-being of both present and future generations. This book raises a number of ethical issues concerning the impact of genetic engineering on generations yet to be born. The four topical areas that constitute the focus of the volume, namely (1) from laboratory to germ-line therapy, (2) the concept of human nature: theological and secular perspectives, (3) genetic intervention and the common heritage view, and (4) social responsibilities of geneticists towards future generations, raise intriguing ethical and legal questions, as well as important policy issues. As much as any set of issues, they reflect the hopes and fears, prejudices and uncertainties that people associate with germ-line intervention and the future of human kind.

Author : Roberta M. Berry
Publisher : Routledge
ISBN 13 : 1135195919
Total Pages : 282 pages
Book Rating : 4.15/5 ( download)

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Download or read book The Ethics of Genetic Engineering written by Roberta M. Berry and published by Routledge. This book was released on 2013-05-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human genetic engineering may soon be possible. The gathering debate about this prospect already threatens to become mired in irresolvable disagreement. After surveying the scientific and technological developments that have brought us to this pass, The Ethics of Genetic Engineering focuses on the ethical and policy debate, noting the deep divide that separates proponents and opponents. The book locates the source of this divide in differing framing assumptions: reductionist pluralist on one side, holist communitarian on the other. The book argues that we must bridge this divide, drawing on the resources from both encampments, if we are to understand and cope with the distinctive problems posed by genetic engineering. These problems, termed "fractious problems," are novel, complex, ethically fraught, unavoidably of public concern, and unavoidably divisive. Berry examines three prominent ethical and political theories – utilitarianism, Kantianism, and virtue ethics – to consider their competency in bridging the divide and addressing these fractious problems. The book concludes that virtue ethics can best guide parental decision making and that a new policymaking approach sketched here, a "navigational approach," can best guide policymaking. These approaches enable us to gain a rich understanding of the problems posed and to craft resolutions adequate to their challenges.

Author : Andrea Boggio
Publisher : Cambridge University Press
ISBN 13 : 1108499872
Total Pages : 681 pages
Book Rating : 4.73/5 ( download)

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Download or read book Human Germline Modification and the Right to Science written by Andrea Boggio and published by Cambridge University Press. This book was released on 2020-01-09 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Author : LeRoy Walters
Publisher : Oxford University Press, USA
ISBN 13 : 9780195059557
Total Pages : 240 pages
Book Rating : 4.57/5 ( download)

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Download or read book The Ethics of Human Gene Therapy written by LeRoy Walters and published by Oxford University Press, USA. This book was released on 1997 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: They start with the current techniques of gene addition, using non-reproductive (somatic) cells in an effort to cure or treat disease. Next they address the technical problems and moral issues facing attempts to prevent disease through genetically modifying early human embryos or sperm and egg cells. These changes would be passed on to future generations. Chapter 4, in many ways the most original part of this volume, confronts the issue of employing genetic means to improve human abilities and appearance.