The Role Of Metal Ions In Biology Biochemistry And Medicine

Author : Michael Moustakas
Publisher : MDPI
ISBN 13 : 3036510540
Total Pages : 180 pages
Book Rating : 4.45/5 ( download)

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Download or read book The Role of Metal Ions in Biology, Biochemistry and Medicine written by Michael Moustakas and published by MDPI. This book was released on 2021-09-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.

Author : Michael Moustakas
Publisher :
ISBN 13 : 9783036510552
Total Pages : 180 pages
Book Rating : 4.59/5 ( download)

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Download or read book The Role of Metal Ions in Biology, Biochemistry and Medicine written by Michael Moustakas and published by . This book was released on 2021 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.

Author : Helmut Sigel
Publisher : CRC Press
ISBN 13 : 9780824779320
Total Pages : 464 pages
Book Rating : 4.20/5 ( download)

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Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1988-08-24 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 44, devoted solely to the vital research areas concerning the biogeochemistry of metals and their transport in the environment and availability to living systems, offers 9 timely and authoritative chapters on these fascinating topics by 19 internationally recognized experts.

Author : Philippe Collery
Publisher : John Libbey Eurotext
ISBN 13 : 9782742002948
Total Pages : 852 pages
Book Rating : 4.44/5 ( download)

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Download or read book Metal Ions in Biology and Medicine written by Philippe Collery and published by John Libbey Eurotext. This book was released on 2000 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the 6th ISMIBM is to foster exchange of opinions between professionals and specialists working on analysis, research and applications of metal ions, trace elements and minerals in biological, biochemical, medical sciences, toxicology and environmental health. The scientific program, composed of plenary and concurrent sessions, and poster presentations is designed to promote intensive and productive dialogue among experts in these fields. A special program with short courses and mini-symposia have also been organised, featuring specialised areas including toxicology, analysis, pathology, remediation strategies, and environmental medicine. Original contributions (oral and/or poster presentations) are invited on the following themes: Metals and Environmental Health; Molecular Toxicology of Metals; Carcinogenicity of Metals; Speciation of Metals and Other Elements; Uses of Metals in Clinical Applications; Metals and Disease: Environmental and Toxicologic Pathology; Epidemiology and Occupational Health; Metals and Aging; Metals and Homeostasis; Effects of Low and High Nutritional Trace Element Status; Metals and Hormone Actions; Metals and Enzyme Activity; Metals and Chelation Therapy; Health Effects of Arsenic; Risk Assessment of Trace Element Status and Health; Advanced Methods for the Analysis of Trace Elements and Metal Ions.

Author : Helmut Sigel
Publisher : CRC Press
ISBN 13 : 9780824777135
Total Pages : 538 pages
Book Rating : 4.31/5 ( download)

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Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1988-03-30 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volumes deal with such topics as the formation, stability, structure, and reactivity of biological compounds of low and high molecular weight containing metal ions; the metabolism and transport of metal ions and their complexes; and new models of complicated natural structures and processes. Devoted solely to the vibrant research area of nickel and its role in biology, Volume 23 offers a comprehensive account of this important subject from the perspectives of 24 distinguished, international authorities. In 11 stimulating, in-depth chapters, Nickel and Its Role in Biology covers nickel and its function in the environment, in aquatic systems, in plants, as well as its metabolism in man and animals ... treats nickel ion binding to amino acids and peptides ... examines nickel in proteins and enzymes, including hydrogenases ... considers the interaction of nickel with nucleic acids and their constituents ... displays thoroughly the toxicology of nickel compounds ... and describes the analysis of nickel in biological materials. With more than 1,400 references to assist further research, Nickel and Its Role in Biology is an essential resource for scientists and students in several disciplines, including biochemistry; bioinorganic, inorganic, and coordination chemistry; biophysics; molecular biology; enzymology; pharmacology; clinical chemistry; nutrition; and toxicology. Book jacket.

Author : Wolfgang Maret
Publisher : Royal Society of Chemistry
ISBN 13 : 1782622829
Total Pages : 938 pages
Book Rating : 4.26/5 ( download)

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Download or read book Binding, Transport and Storage of Metal Ions in Biological Cells written by Wolfgang Maret and published by Royal Society of Chemistry. This book was released on 2014-07-09 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

Author : Helmut Sigel
Publisher : CRC Press
ISBN 13 : 9780824775407
Total Pages : 416 pages
Book Rating : 4.06/5 ( download)

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Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1986-02-21 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volumes deal with such topics as the formation, stability, structure, and reactivity of biological compounds of low and high molecular weight containing metal ions; the metabolism and transport of metal ions and their complexes; and new models of complicated natural structures and processes. Volume 21 describes the underlying theories of nuclear magnetic resonance (NMR), promoting a wider use of NMR in studies of paramagnetic species. In six concise chapters by leading international authorities, Applications of Nuclear Magnetic Resonance to Paramagnetic Species outlines the most recent developments regarding the use of nuclear relaxation as a source for structural information ... examines studies of magnetically coupled metalloproteins and metal-porphyrin induced dipolar shifts for conformational analysis ... and evaluates the potential of paramagnetic ions as agents for enhancing NMR image contrast. With over 500 references that facilitate further research, Applications of Nuclear Magnetic Resonance to Paramagnetic Species is an essential resource for scientists and students in such disciplines as biophysics; bioinorganic, inorganic, and coordination chemistry; biochemistry; molecular biology; and enzymology. Book jacket.

Author : Astrid Sigel
Publisher : Springer
ISBN 13 : 3319217569
Total Pages : 663 pages
Book Rating : 4.67/5 ( download)

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Download or read book The Alkali Metal Ions: Their Role for Life written by Astrid Sigel and published by Springer. This book was released on 2016-02-09 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.

Author : Astrid Sigel
Publisher : CRC Press
ISBN 13 : 9780824793838
Total Pages : 828 pages
Book Rating : 4.38/5 ( download)

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Download or read book Metal Ions in Biological Systems written by Astrid Sigel and published by CRC Press. This book was released on 1995-02-22 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Volume 31, devoted solely to the role of vanadium in life processes, offers a comprehensive and timely account of this fascinating field by 37 distinguished, international authorities. Highlights the properties of the various oxidation states of vanadium, their affinity for biogenic ligands, the effects of vanadium species on enzyme activity, the role of vanadium in nitrogenases and haloperoxidases, and more."

Author : Astrid Sigel
Publisher : CRC Press
ISBN 13 : 9780203913703
Total Pages : 578 pages
Book Rating : 4.01/5 ( download)

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Download or read book Metal Ions in Biological Systems written by Astrid Sigel and published by CRC Press. This book was released on 2004-03-26 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions are currently used for such applications as diabetes, anti-inflammatory, rheumatoid arthritis, psychiatric, and anti-ulcer medications, using compounds of vanadium, copper and zinc, gold, lithium, and bismuth, respectively. This text explores these applications in addition to an assessment of chelation therapy, uses in environmental sciences, and the human health effects of metal ion deficiency for several elements-magnesium, calcium, zinc, and iron. Featuring contributions from 29 internationally recognized experts, this book offers a timely, authoritative look at ionic complexes in medicine.