The Pulmonary Endothelium

Author : Norbert Voelkel
Publisher : John Wiley & Sons
ISBN 13 : 9780470747506
Total Pages : 532 pages
Book Rating : 4.01/5 ( download)

DOWNLOAD NOW!

Download or read book The Pulmonary Endothelium written by Norbert Voelkel and published by John Wiley & Sons. This book was released on 2009-08-25 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals – specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.

Author : Mary I. Townsley
Publisher : Biota Publishing
ISBN 13 : 1615044493
Total Pages : 68 pages
Book Rating : 4.98/5 ( download)

DOWNLOAD NOW!

Download or read book Lung Endothelium written by Mary I. Townsley and published by Biota Publishing. This book was released on 2015-09-01 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary endothelium forms the inner lining of blood vessels, where it interprets the complex mechanical and chemical environment within the circulation and adjusts its behavior to facilitate vascular homeostasis. Although endothelium fulfills many essential functions, including regulation of vascular pressure, circulating cell transmigration, coagulation, and hormone metabolism and/or delivery, a principal role is to form a semi-permeable barrier that limits fluid, solute and macromolecular access to the interstitial space. Physiological properties that govern such permeability characteristics are defined by the Starling equation, which assumes that endothelial cells throughout the circulation are all alike. However, in recent years it has become evident that endothelial cells in pulmonary arteries, capillary and veins are heterogeneous in structure and function. Here, we review evidence for endothelial heterogeneity among these pulmonary vascular segments, and consider the implications for such heterogeneity in lung fluid balance, especially as it relates to the Starling equation.

Author :
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.30/5 ( download)

DOWNLOAD NOW!

Download or read book Report of Workshop on the Pulmonary Endothelial Cell written by and published by . This book was released on 1978 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Toshio Nakanishi
Publisher : Springer Nature
ISBN 13 : 9811511853
Total Pages : 374 pages
Book Rating : 4.51/5 ( download)

DOWNLOAD NOW!

Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Author : Una S. Ryan
Publisher : CRC Press
ISBN 13 : 9780824777586
Total Pages : 520 pages
Book Rating : 4.81/5 ( download)

DOWNLOAD NOW!

Download or read book Pulmonary Endothelium in Health and Disease written by Una S. Ryan and published by CRC Press. This book was released on 1987-07-20 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.04/5 ( download)

DOWNLOAD NOW!

Download or read book Report of Workshop on the Pulmonary Endothelial Cell written by and published by . This book was released on 1978 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Helena Lenasi
Publisher : BoD – Books on Demand
ISBN 13 : 1789842530
Total Pages : 432 pages
Book Rating : 4.31/5 ( download)

DOWNLOAD NOW!

Download or read book Endothelial Dysfunction written by Helena Lenasi and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.

Author : William C. Aird
Publisher : Cambridge University Press
ISBN 13 : 1139465872
Total Pages : 25 pages
Book Rating : 4.78/5 ( download)

DOWNLOAD NOW!

Download or read book Endothelial Biomedicine written by William C. Aird and published by Cambridge University Press. This book was released on 2007-09-03 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all areas of the human body. Clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. The endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume bridges the bench-to-bedside gap in endothelial biomedicine, advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. It's interdisciplinary approach, which draws on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

Author : C.E. Patterson
Publisher : Elsevier
ISBN 13 : 0444518347
Total Pages : 540 pages
Book Rating : 4.47/5 ( download)

DOWNLOAD NOW!

Download or read book Perspectives on Lung Endothelial Barrier Function written by C.E. Patterson and published by Elsevier. This book was released on 2005-04 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers endothelial biology from the fundamentals of structure and lung fluid balance physiology to descriptions of the molecular mechanisms involved in the development of lung failure. This illustrated text provides the knowledge of endothelial function, vascular integrity, pulmonary function, and pathophysiology in respiratory failure.

Author : Goldie
Publisher : Springer
ISBN 13 : 303488821X
Total Pages : 292 pages
Book Rating : 4.19/5 ( download)

DOWNLOAD NOW!

Download or read book Pulmonary Actions of the Endothelins written by Goldie and published by Springer. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biology of the family of endogenous autocrine peptides known as the endothelins (ETs) has been a source of intense study for researchers since 1988, following the identification of ET-l as the previously described endothelium-derived contractile factor. Initial interest focussed on the actions of the ETs in the cardiovascular system, and this remains the pri mary source of published work involving these peptides. Importantly, evi dence is mounting for a significant mediator role for ET-l in cardiovascu lar diseases including systemic hypertension and congestive heart failure. However, it was also recognized early on that the ETs exert an array of powerful actions in the respiratory tract, many of which prompted specula tion concerning mediator roles for ET-l in several lung diseases including asthma and pulmonary hypertension. In recent years the evidence for the involvement of ET-l in lung diseases has become more compelling. There is now real hope and anticipation that novel ET receptor antagonists may eventually be used therapeutically against asthma and other major lung pathologies. It is this atmosphere of excitement created by new discoveries and the increasing scientific ratio nale for a significant impact ofthe ETs in pulmonary diseases that prompt ed the creation of this book, the first on this topic. Most of the information presented relates to ET-l, which is the most widely studied member of the ET family.