The Dynamic Architecture Of A Developing Organism

Author : L.V. Beloussov
Publisher : Springer Science & Business Media
ISBN 13 : 9401589984
Total Pages : 243 pages
Book Rating : 4.87/5 ( download)

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Download or read book The Dynamic Architecture of a Developing Organism written by L.V. Beloussov and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: For anybody capable of an emotional response to it, any view of a developing organism should give birth to a feeling of amazement and even admiration, whether this development is seen directly, or in the form of a time lapse film, or even if mentally reconstructed from a series of static images. We ask ourselves how such seemingly primitive eggs or pieces of tissue, without any obvious intervention from outside, so regularly transform themselves into precisely constructed adult organisms. If we try to formulate what amazes us most of all about development, the answer will probably be that it is the internal capacity of developing organisms themselves to create new structures. How, then, can we satisfy our amazement in ways that are more or less reasonable, as well as scientifically valuable? This depends, first of all, on what position we choose to regard embryonic development as occupying among other structure creating processes, even including human activities. On the one hand, one might regard the development of organisms as a highly specialized class of processes, unique to themselves and alien to the general laws of nature, or at least not derivable from them and more akin to the deliberate acts of our own human behaviour. In that case our task would become reduced to a search for some specific 'instructions' for each next member of such a class. Whether in an overt or hidden form, some such ideology seems to dominate in present day developmental biology.

Author : Anton Crombach
Publisher : Springer Nature
ISBN 13 : 3030717372
Total Pages : 299 pages
Book Rating : 4.77/5 ( download)

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Download or read book Evolutionary Systems Biology written by Anton Crombach and published by Springer Nature. This book was released on 2021-08-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.

Author : Alessandro Minelli
Publisher : Oxford University Press
ISBN 13 : 0199671427
Total Pages : 299 pages
Book Rating : 4.27/5 ( download)

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Download or read book Towards a Theory of Development written by Alessandro Minelli and published by Oxford University Press. This book was released on 2014 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is it possible to explain and predict the development of living things? What is development? Answers to these innocuous questions are far from straightforward. To date, no systematic, targeted effort has been made to construct a unifying theory of development. This text offers a unique exploration of the foundations of ontogeny by asking how the development of living things should be understood. It explores the key concepts of developmental biology, asks whether general principles of development can be discovered, and examines the role of models and theories. This book analyses a wealth of approaches to concepts, models and theories of development, such as gene regulatory networks, accounts based on systems biology and on physics of soft matter, the different articulations of evolution and development, symbiont-induced development, as well as the widely discussed concepts of positional information and morphogenetic field, the idea of a 'programme' of development and its critiques, and the long-standing opposition between preformationist and epigenetic conceptions of development. --

Author : Lev V. Beloussov
Publisher : Springer
ISBN 13 : 3319139908
Total Pages : 195 pages
Book Rating : 4.06/5 ( download)

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Download or read book Morphomechanics of Development written by Lev V. Beloussov and published by Springer. This book was released on 2014-12-27 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines a unified theory of embryonic development, assuming morphogenesis to be a multi-level process including self-organizing steps while also obeying general laws. It is shown how molecular mechanisms generate mechanical forces, which in the long run lead to morphological changes. Questions such as how stress-mediated feedback acts at the cellular and supra-cellular levels and how executive and regulatory mechanisms are mutually dependent are addressed, while aspects of collective cell behavior and the morphogenesis of plants are also discussed. The morphomechanical approach employed in the book is based on the general principles of self-organization theory.

Author : Roberto Lent
Publisher : Frontiers Media SA
ISBN 13 : 2889198898
Total Pages : 132 pages
Book Rating : 4.94/5 ( download)

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Download or read book How Can Development and Plasticity Contribute to Understanding Evolution of the Human Brain? written by Roberto Lent and published by Frontiers Media SA. This book was released on 2016-07-19 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans usually attribute themselves the prerogative of being the pinnacle of evolution. They have large brains with many billion neurons and glial cells, trillions of synapses and besides all, a plastic hardware that may change either subtly or strongly in response to the external environment and internal, mental commands. With this hypercomplex apparatus, they are capable of very sophisticated inward computations and outward behaviors that include self-recognition, metacognition, different forms of language expression and reception, prediction of future events, planning and performing long streams of motor acts, subtle emotional feelings, and many other surprising, almost unbelievable properties. The main challenge for research is: how do we explain this gigantic achievement of evolution? Is it a direct consequence of having acquired a brain larger than our primate ancestors, with huge numbers of computational units? Would it be determined by a particular way these units came to relate to each other, building up logic circuits of powerful capacities? What along development has “made the difference” for the construction of such a complex brain machine? How much of this complexity is innate, how much is sculpted by influence of the external world, by social interaction with our human fellows, and by the history of our own mental trajectory along life? Many specific questions can be asked (albeit not necessarily answered so far) to this purpose: (1) which genomic characteristics make us unique among primates? (2) which of developmental events during and beyond embryogenesis define our brain – prolonged neurogenesis? permanent circuit (re)formation? dynamic synaptogenesis? regressive sculpting of the hardware? all of them? (3) is there anything special about plasticity of the human brain that allows us to build the exquisite individual variability characteristic of our brains? Neuroscience is in need of a synthesis. Perhaps associating concepts derived from developmental neurobiology with evolutionary morphology and physiology, together with those that photograph the human brain in action under influence of the external world, would turn on a light at the end of the tunnel, and we would be able to understand what humans do have that is special – if anything – to explain our success in the Earth.

Author : Rafael Beyar
Publisher : John Wiley & Sons
ISBN 13 : 1573317470
Total Pages : 241 pages
Book Rating : 4.74/5 ( download)

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Download or read book Analysis of Cardiac Development written by Rafael Beyar and published by John Wiley & Sons. This book was released on 2010-03-22 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, the result of three days of interactive sessions among world leaders in the cardiac sciences, summarizes the most up-to-date information about development and cardiogenesis signaling in cell-based therapy, as well as developmental aspects of the formation of the embryonic heart, including the effect of mechanical load on differentiation. Other topics covered include: signaling and repair strategies, cell and gene therapy for the treatment of postmyocardial infarction, signaling, vascularization methods in engineering embryonic cardiac tissue, and molecular methods to improve survival of human embryonic stem cell–derived cardiomyocytes; developmental and evolutional cardiology; novel strategies for treatment of atrial fibrillation and channel molecular physiology in remodeling and hypertrophy; multiscale modeling for metabolism and flows, including force development, mechanics of cardiac contraction, and ATP supply and demand aspects; aging, interactions, and interference aspects include fibroblast-myocyte-capillary communications, nonuniformities in contraction, calcium channels as oxygen sensors, and epigenetics of heart failure; and macroscale phenomena and clinical aspects, including various clinical aspects of modern cardiology such as navigation methods for cardiac interventions and control of cardiac function by changes in energetic demand. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Author : Natalie K Gordon retired
Publisher : World Scientific
ISBN 13 : 9814740691
Total Pages : 784 pages
Book Rating : 4.92/5 ( download)

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Download or read book Embryogenesis Explained written by Natalie K Gordon retired and published by World Scientific. This book was released on 2016-09-15 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time. As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.

Author : Gabor Forgacs
Publisher : Cambridge University Press
ISBN 13 : 9781139447317
Total Pages : 354 pages
Book Rating : 4.19/5 ( download)

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Download or read book Biological Physics of the Developing Embryo written by Gabor Forgacs and published by Cambridge University Press. This book was released on 2005-11-24 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book shows how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus. Physical concepts introduced include diffusion, viscosity and elasticity, adhesion, dynamical systems, electrical potential, percolation, fractals, reaction-diffusion systems, and cellular automata. With full-color figures throughout, this comprehensive textbook teaches biophysics by application to developmental biology and is suitable for graduate and upper-undergraduate courses in physics and biology.

Author : Kathryn E. Hood
Publisher : John Wiley & Sons
ISBN 13 : 1444351680
Total Pages : 772 pages
Book Rating : 4.82/5 ( download)

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Download or read book Handbook of Developmental Science, Behavior, and Genetics written by Kathryn E. Hood and published by John Wiley & Sons. This book was released on 2011-06-28 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Developmental Science, Behavior, and Genetics brings together the cutting-edge theory, research and methodology that contribute to our current scientific understanding of the role of genetics in the developmental system. • Commemorates the historically important contributions made by Gilbert Gottlieb in comparative psychology and developmental science • Includes an international group of contributors who are among the most respected behavioral and biological scientists working today • Examines the scientific basis for rejecting the reductionism and counterfactual approach to understanding the links between genes, behavior, and development • Documents the current status of comparative psychology and developmental science and provides the foundation for future scientific progress in the field

Author : James Terrence Kelly
Publisher : Nova Publishers
ISBN 13 : 9781604561715
Total Pages : 366 pages
Book Rating : 4.18/5 ( download)

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Download or read book Progress in Mathematical Biology Research written by James Terrence Kelly and published by Nova Publishers. This book was released on 2008 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying mathematics to biology has a long history, but only recently has there been an explosion of interest in the field. Some reasons for this include: the explosion of data-rich information sets, due to the genomics revolution, which are difficult to understand without the use of analytical tools, recent development of mathematical tools such as chaos theory to help understand complex, non-linear mechanisms in biology, an increase in computing power which enables calculations and simulations to be performed that were not previously possible, and an increasing interest in in-silico experimentation due to the complications involved in human and animal research. This new book presents the latest leading-edge research in the field.