The Causes Of Molecular Evolution

Author : John H. Gillespie
Publisher : Oxford University Press
ISBN 13 : 0195357744
Total Pages : 351 pages
Book Rating : 4.45/5 ( download)

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Download or read book The Causes of Molecular Evolution written by John H. Gillespie and published by Oxford University Press. This book was released on 1994-05-26 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.

Author :
Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.95/5 ( download)

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Download or read book The Causes of Molecular Evolution written by and published by . This book was released on 1991 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Motoo Kimura
Publisher : Cambridge University Press
ISBN 13 : 1139935674
Total Pages : 388 pages
Book Rating : 4.78/5 ( download)

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Download or read book The Neutral Theory of Molecular Evolution written by Motoo Kimura and published by Cambridge University Press. This book was released on 1985-01-10 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.

Author : Motoo Kimura
Publisher : University of Chicago Press
ISBN 13 : 9780226435633
Total Pages : 736 pages
Book Rating : 4.36/5 ( download)

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Download or read book Population Genetics, Molecular Evolution, and the Neutral Theory written by Motoo Kimura and published by University of Chicago Press. This book was released on 1994 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

Author : Simon Y. W. Ho
Publisher : Springer Nature
ISBN 13 : 3030601811
Total Pages : 245 pages
Book Rating : 4.12/5 ( download)

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Download or read book The Molecular Evolutionary Clock written by Simon Y. W. Ho and published by Springer Nature. This book was released on 2021-01-18 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution.

Author : Motoo Kimura
Publisher : Cambridge University Press
ISBN 13 : 9780521317931
Total Pages : 388 pages
Book Rating : 4.32/5 ( download)

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Download or read book The Neutral Theory of Molecular Evolution written by Motoo Kimura and published by Cambridge University Press. This book was released on 1983 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive treatment of this subject.

Author : Lindell Bromham
Publisher : Oxford University Press
ISBN 13 : 0198736363
Total Pages : 533 pages
Book Rating : 4.63/5 ( download)

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Download or read book An Introduction to Molecular Evolution and Phylogenetics written by Lindell Bromham and published by Oxford University Press. This book was released on 2016 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous edition published as Reading the story in DNA: a beginner's guide to molecular evolution by Oxford University Press, 2008.

Author : Masatoshi Nei
Publisher : Oxford University Press
ISBN 13 : 0199881227
Total Pages : 352 pages
Book Rating : 4.22/5 ( download)

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Download or read book Molecular Evolution and Phylogenetics written by Masatoshi Nei and published by Oxford University Press. This book was released on 2000-07-27 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Author : Roderick D.M. Page
Publisher : John Wiley & Sons
ISBN 13 : 1444313363
Total Pages : 352 pages
Book Rating : 4.69/5 ( download)

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Download or read book Molecular Evolution written by Roderick D.M. Page and published by John Wiley & Sons. This book was released on 2009-07-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Author : Masatoshi Nei
Publisher : Oxford University Press
ISBN 13 : 0195350510
Total Pages : 348 pages
Book Rating : 4.17/5 ( download)

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Download or read book Molecular Evolution and Phylogenetics written by Masatoshi Nei and published by Oxford University Press. This book was released on 2000-07-27 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.