The Biochemical Pathology Of Astrocytes

Author : Michael D. Norenberg
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.96/5 ( download)

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Download or read book The Biochemical Pathology of Astrocytes written by Michael D. Norenberg and published by . This book was released on 1988 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes have been associated with a number of neuropsychiatric disorders. This edited volume reviews the state of knowledge on the role of astrocytes in such neuropsychiatric conditions as anoxia/ischemia, edema, epilepsy, demyelinative disorders, degenerative diseases, toxic-metabolic encephalopathies, psychiatric abnormalities, and the role of reactive astrocytes in various pathologic states.

Author : Michael D. Norenberg
Publisher : Wiley-Liss
ISBN 13 : 9780471614395
Total Pages : 662 pages
Book Rating : 4.94/5 ( download)

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Download or read book The Biochemical Pathology of Astrocytes written by Michael D. Norenberg and published by Wiley-Liss. This book was released on 1988-04-28 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes have been associated with a number of neuropsychiatric disorders. This edited volume reviews the state of knowledge on the role of astrocytes in such neuropsychiatric conditions as anoxia/ischemia, edema, epilepsy, demyelinative disorders, degenerative diseases, toxic-metabolic encephalopathies, psychiatric abnormalities, and the role of reactive astrocytes in various pathologic states.

Author : Sergey Fedorff
Publisher : Elsevier
ISBN 13 : 0323148557
Total Pages : 487 pages
Book Rating : 4.59/5 ( download)

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Download or read book Astrocytes Pt 3: Biochemistry, Physiology, and Pharmacology of Astrocytes written by Sergey Fedorff and published by Elsevier. This book was released on 2012-12-02 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes: Cell Biology and Pathology of Astrocytes, Volume 3 deals with the involvement of astrocytes in neurological and neuropathological states of brain function. This volume discusses the expression of astrocyte-specific immunological markers and plasma membrane structures; the dynamics of the cytoskeleton and cell cycle; and the reactivity to injury and response of astrocytes in selected pathological and genetic states. The text also aims to inspire new ideas and research on astrocyte functions as well as on the pathogenesis of neurological disorders. Neuroscientists, cell biologists, clinicians, neuropathologists, and pediatric neurologists will find the book invaluable.

Author : Maria Teresa Gentile
Publisher : BoD – Books on Demand
ISBN 13 : 9535138855
Total Pages : 244 pages
Book Rating : 4.53/5 ( download)

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Download or read book Astrocyte written by Maria Teresa Gentile and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS and in the pathogenesis of several CNS disorders suggesting that the shift from a neurocentric view to one that incorporates astrocytes in disease models for drug discovery is a critical step in renewing drug development strategies to treat neurodegenerative diseases.

Author : Sergey Fedoroff
Publisher : Springer Science & Business Media
ISBN 13 : 147579486X
Total Pages : 452 pages
Book Rating : 4.61/5 ( download)

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Download or read book Biology and Pathology of Astrocyte-Neuron Interactions written by Sergey Fedoroff and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is made up of papers presented at the Second International Altschul Symposium: Biology and Pathology of Astrocyte-Neuron Interactions. The symposium was held in Saskatoon, Canada at the University of Saskatchewn in May, 1992 in memory of Rudolf Altschul, a graduate of the University of Prague and a pioneer in the fields of the biology of the vascular and nervous systems. Dr. Altschul was Professor and Head of the Department of Anatomy at the University of Saskatchewan from 1955 to 1963. The Altschul Symposia were made possible by an endowment left by Anni Altschul and by other contributions. The symposia are held biennially. One of the greatest challenges for present day scientists is to uncover the mechanisms of brain function. Although cellular anatomy of the nervous system has already been well outlined and indeed was delineated by the beginning of the century, experimental analysis of the function of the brain is relatively recent. The framework of the brain is made up of stellate cells, the astrocytes, which are interconnected by means of their processes, thus presenting a meshwork through which the neurons send their axons, accompanied by oligodendrocytes. Microglia are distributed throughout the brain.

Author : Vladimir Parpura
Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.21/5 ( download)

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Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Author : Uday Kishore
Publisher : BoD – Books on Demand
ISBN 13 : 9535110888
Total Pages : 642 pages
Book Rating : 4.80/5 ( download)

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Download or read book Neurodegenerative Diseases written by Uday Kishore and published by BoD – Books on Demand. This book was released on 2013-05-15 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

Author : Alan C. Jackson
Publisher : Academic Press
ISBN 13 : 0080550096
Total Pages : 681 pages
Book Rating : 4.91/5 ( download)

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Download or read book Rabies written by Alan C. Jackson and published by Academic Press. This book was released on 2010-07-26 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rabies is the most current and comprehensive account of one of the oldest diseases known that remains a significant public health threat despite the efforts of many who have endeavored to control it in wildlife and domestic animals. During the past five years since publication of the first edition there have been new developments in many areas on the rabies landscape. This edition takes on a more global perspective with many new authors offering fresh outlooks on each topic. Clinical features of rabies in humans and animals are discussed as well as basic science aspects, molecular biology, pathology, and pathogenesis of this disease. Current methods used in defining geographic origins and animal species infected in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. This multidisciplinary account is essential for clinicians as well as public health advisors, epidemiologists, wildlife biologists, and research scientists wanting to know more about the virus and the disease it causes. Offers a unique global perspective on rabies where dog rabies is responsible for killing more people than yellow More than 7 million people are potentially exposed to the virus annually and about 50,000 people, half of them children, die of rabies each year New edition includes greatly expanded coverage of bat rabies which is now the most prominent source of human rabies in the New World and Western Europe, where dog rabies has been controlled Recent successes of controlling wildlife rabies with an emphasis on prevention is discussed Approximately 40% updated material incorporates recent knowledge on new approaches to therapy of human rabies as well as issues involving organ and tissue transplantation Includes an increase in illustrations to more accurately represent this diseases’ unique horror

Author : Gabor G. Kovacs
Publisher : Cambridge University Press
ISBN 13 : 1316337650
Total Pages : 320 pages
Book Rating : 4.53/5 ( download)

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Download or read book Neuropathology of Neurodegenerative Diseases written by Gabor G. Kovacs and published by Cambridge University Press. This book was released on 2017-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

Author : Michael Aschner
Publisher : CRC Press
ISBN 13 : 1420039741
Total Pages : 477 pages
Book Rating : 4.40/5 ( download)

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Download or read book The Role of Glia in Neurotoxicity written by Michael Aschner and published by CRC Press. This book was released on 2004-12-28 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.