Targeting Thyroid Cancer Microenvironment And Epigenetic Signalling New Frontiers In Cancer Endocrinology Basic And Clinical Research 2nd Edition

Author : Carmelo Nucera
Publisher : Frontiers Media SA
ISBN 13 : 2889661989
Total Pages : 133 pages
Book Rating : 4.85/5 ( download)

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Download or read book Targeting Thyroid Cancer Microenvironment and Epigenetic Signalling: New Frontiers in Cancer Endocrinology Basic and Clinical Research, 2nd Edition written by Carmelo Nucera and published by Frontiers Media SA. This book was released on with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.68/5 ( download)

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Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Author : Kelly Power-Kean
Publisher : Elsevier Health Sciences
ISBN 13 : 0323778852
Total Pages : 1229 pages
Book Rating : 4.55/5 ( download)

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Download or read book Huether and McCance's Understanding Pathophysiology, Canadian Edition - E-Book written by Kelly Power-Kean and published by Elsevier Health Sciences. This book was released on 2022-01-08 with total page 1229 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Textbook and Academic Authors Association (TAA) Textbook Excellence Award Winner, 2024** Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition covers the basic concepts of pathophysiology and disease processes from a Canadian perspective. Clear descriptions and vibrant illustrations make it easier to understand body systems and the mechanisms of disease, and online resources bring pathophysiology concepts to life. Developed for Canadian nursing students by educators Kelly Power-Kean, Stephanie Zettel, and Mohamed Toufic El-Hussein, this text prepares students for success on the Next Generation NCLEX®, CPNRE®, and REx-PNTM and also in clinical practice. Introduction to Pathophysiology provides an entrance to the science of pathophysiology and explains why it is important. Lifespan coverage includes nine separate chapters on developmental alterations in pathophysiology and special sections with aging and pediatrics content. Canadian drug and treatment guidelines familiarize you with aspects of clinical practice you will encounter. Coverage of diseases includes their pathophysiology, clinical manifestations, and evaluation and treatment. Canadian lab values provide the core fundamental information required for practice in Canada. Canadian morbidity statistics provide you with the Canadian context in which you will be practising. Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes. Health Promotion boxes emphasize evidence-based care and align with the Canadian curriculum. Risk Factors boxes highlight important safety considerations associated with specific diseases. Quick Check boxes test your understanding of important chapter concepts. End-of-chapter Did You Understand? summaries make it easy to review the chapter’s major concepts. Key Terms are set in blue, boldface type and listed at the end of each chapter Glossary of approximately 1,000 terms is included on the Evolve website with definitions of important terminology.

Author : Dil Afroze
Publisher : BoD – Books on Demand
ISBN 13 : 1789239613
Total Pages : 127 pages
Book Rating : 4.14/5 ( download)

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Download or read book Breast Cancer Biology written by Dil Afroze and published by BoD – Books on Demand. This book was released on 2020-07-08 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them tremendous diversity of perspectives and fields, which is truly reflective of the complexity of the topic, and they have come together in this project to serve as the node of multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies, and who have inspired us to gather information to significantly progress knowledge in the field in recent years.

Author : Lev M. Berstein
Publisher : Springer Science & Business Media
ISBN 13 : 0387788182
Total Pages : 242 pages
Book Rating : 4.80/5 ( download)

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Download or read book Innovative Endocrinology of Cancer written by Lev M. Berstein and published by Springer Science & Business Media. This book was released on 2009-12-04 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is devoted to new developments in a huge range of topics, such as the mechanisms of hormonal carcinogenesis, epidemiology and risk factors, hormone production by tumor tissue and antihormonal therapy of cancer and its prevention.

Author : Sabita Saldanha
Publisher : Academic Press
ISBN 13 : 9780128095522
Total Pages : 0 pages
Book Rating : 4.20/5 ( download)

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Download or read book Epigenetic Mechanisms in Cancer written by Sabita Saldanha and published by Academic Press. This book was released on 2017-11-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.

Author : Eric J. Bieber
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.97/5 ( download)

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Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Author : James W. Janetka
Publisher : John Wiley & Sons
ISBN 13 : 1119300185
Total Pages : 482 pages
Book Rating : 4.82/5 ( download)

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Download or read book Extracellular Targeting of Cell Signaling in Cancer written by James W. Janetka and published by John Wiley & Sons. This book was released on 2018-07-23 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: International experts present innovative therapeutic strategies to treat cancer patients and prevent disease progression Extracellular Targeting of Cell Signaling in Cancer highlights innovative therapeutic strategies to treat cancer metastasis and prevent tumor progression. Currently, there are no drugs available to treat or prevent metastatic cancer other than non-selective, toxic chemotherapy. With contributions from an international panel of experts in the field, the book integrates diverse aspects of biochemistry, molecular biology, protein engineering, proteomics, cell biology, pharmacology, biophysics, structural biology, medicinal chemistry and drug development. A large class of proteins called kinases are enzymes required by cancer cells to grow, proliferate, and survive apoptosis (death) by the immune system. Two important kinases are MET and RON which are receptor tyrosine kinases (RTKs) that initiate cell signaling pathways outside the cell surface in response to extracellular ligands (growth factors.) Both kinases are oncogenes which are required by cancer cells to migrate away from the primary tumor, invade surrounding tissue and metastasize. MET and RON reside on both cancer cells and the support cells surrounding the tumor, called the microenvironment. MET and RON are activated by their particular ligands, the growth factors HGF and MSP, respectively. Blocking MET and RON kinase activation and downstream signaling is a promising therapeutic strategy for preventing tumor progression and metastasis. Written for cancer physicians and biologists as well as drug discovery and development teams in both industry and academia, this is the first book of its kind which explores novel approaches to inhibit MET and RON kinases other than traditional small molecule kinase inhibitors. These new strategies target key tumorigenic processes on the outside of the cell, such as growth factor activation by proteases. These unique strategies have promising potential as an improved alternative to kinase inhibitors, chemotherapy, or radiation treatment.

Author : Carlo C. Maley
Publisher : Springer
ISBN 13 : 1493964607
Total Pages : 258 pages
Book Rating : 4.04/5 ( download)

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Download or read book Frontiers in Cancer Research written by Carlo C. Maley and published by Springer. This book was released on 2016-11-21 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer susceptibility in humans due to a mismatch between our modern environment and the environment in which our ancestors evolved, as well as a chapter on the evolution of cancer suppression mechanisms that have evolved in different species, particularly the large long-lived animals like elephants and whales that are better at suppressing cancers than humans. This book serves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.

Author : Gary S. Stein
Publisher : John Wiley & Sons
ISBN 13 : 1118962885
Total Pages : 708 pages
Book Rating : 4.86/5 ( download)

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Download or read book Cancer written by Gary S. Stein and published by John Wiley & Sons. This book was released on 2019-09-18 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.