Synaptic Transmission

Author : Stephen D. Meriney
Publisher : Academic Press
ISBN 13 : 0128153210
Total Pages : 528 pages
Book Rating : 4.15/5 ( download)

DOWNLOAD NOW!

Download or read book Synaptic Transmission written by Stephen D. Meriney and published by Academic Press. This book was released on 2019-06-12 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic

Author : Elliot S. Valenstein
Publisher : Columbia University Press
ISBN 13 : 0231509731
Total Pages : 381 pages
Book Rating : 4.32/5 ( download)

DOWNLOAD NOW!

Download or read book The War of the Soups and the Sparks written by Elliot S. Valenstein and published by Columbia University Press. This book was released on 2005-07-15 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like the cracking of the genetic code and the creation of the atomic bomb, the discovery of how the brain's neurons work is one of the fundamental scientific developments of the twentieth century. The discovery of neurotransmitters revolutionized the way we think about the brain and what it means to be human yet few people know how they were discovered, the scientists involved, or the fierce controversy about whether they even existed. The War of the Soups and the Sparks tells the saga of the dispute between the pharmacologists, who had uncovered the first evidence that nerves communicate by releasing chemicals, and the neurophysiologists, experts on the nervous system, who dismissed the evidence and remained committed to electrical explanations. The protagonists of this story are Otto Loewi and Henry Dale, who received Nobel Prizes for their work, and Walter Cannon, who would have shared the prize with them if he had not been persuaded to adopt a controversial theory (how that happened is an important part of this history). Valenstein sets his story of scientific discovery against the backdrop of two world wars and examines the fascinating lives of several scientists whose work was affected by the social and political events of their time. He recounts such stories as Loewi's arrest by Nazi storm troopers and Dale's efforts at helping key scientists escape Germany. The War of the Soups and the Sparks reveals how science and scientists work. Valenstein describes the observations and experiments that led to the discovery of neurotransmitters and sheds light on what determines whether a novel concept will gain acceptance among the scientific community. His work also explains the immense importance of Loewi, Dale, and Cannon's achievements in our understanding of the human brain and the way mental illnesses are conceptualized and treated.

Author : Nicholas Graziane
Publisher : Humana
ISBN 13 : 9781071625910
Total Pages : 0 pages
Book Rating : 4.18/5 ( download)

DOWNLOAD NOW!

Download or read book Electrophysiological Analysis of Synaptic Transmission written by Nicholas Graziane and published by Humana. This book was released on 2023-08-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Author : Wulfram Gerstner
Publisher : Cambridge University Press
ISBN 13 : 1107060834
Total Pages : 591 pages
Book Rating : 4.38/5 ( download)

DOWNLOAD NOW!

Download or read book Neuronal Dynamics written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2014-07-24 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.

Author : Scott Brady
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1120 pages
Book Rating : 4.16/5 ( download)

DOWNLOAD NOW!

Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

Author : Hugo J. Bellen
Publisher :
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.38/5 ( download)

DOWNLOAD NOW!

Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by . This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the mechanisms that underlie brain activity and function remains one of the major frontiers of biology. All the processes of how we co-ordinate our movements, sense our surroundings, react to stimuli and learn and retain information rely on complicated networks of neurons thatcommunicate with each other and their targets. This fast and accurate intercellular signalling most occurs at synapses, specialized processes of neurons that release chemical signals, called neurotransmitters. Neurotransmitters: Frontiers in Molecular Biology will provide the reader withextensive background information on neurotransmitter release. It takes a multidisciplinary approach, but does not assume previous knowledge having basic introductions to most topics. Topics however are covered in enough detail to be of interest to experts in the field. Throughout, emphasis is placedon the rationale by which proteins are assigned specific functions rather than just providing facts about function. The first chapter provides an introduction to the basic features and properties of the synapse and is followed by a chapter detailing several important techniques used to elucidatevarious aspects of release. Chapters 3 describes many of the biochemical approaches used to identify proteins involved in neurotransmitter release and then chapters 4 and 5 focus on more specific aspects of synaptic transmission: the proteins that transport neurotransmitters and the role ofphosphlipids in the process. The next five chapters concentrate on approaches to unravel the function of many proteins in vivo by using toxins, giant squid axons, C. elegans, Drosophila, and mice. The final chapter summarizes current knowledge on endocytosis and recycling. Knowledge of themolecular mechanisms underlying neurotransmitter release has expanded tremendously over the last 10 years. Many of the proteins involved have been isolated, but their roles have yet to be determined. These discoveries will be a major challenge and it is therefore the major aim of this book not onlyto provide information but also to generate excitement.

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.45/5 ( download)

DOWNLOAD NOW!

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : R. D. Keynes
Publisher : Cambridge University Press
ISBN 13 : 9780521805841
Total Pages : 196 pages
Book Rating : 4.48/5 ( download)

DOWNLOAD NOW!

Download or read book Nerve and Muscle written by R. D. Keynes and published by Cambridge University Press. This book was released on 2001-03-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential textbook for all undergraduate students of neurobiology, physiology, cell biology and preclinical medicine.

Author : George J. Siegel
Publisher : Lippincott Raven
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.11/5 ( download)

DOWNLOAD NOW!

Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Author : Lars Svennerholm
Publisher : Springer Science & Business Media
ISBN 13 : 1468478443
Total Pages : 556 pages
Book Rating : 4.40/5 ( download)

DOWNLOAD NOW!

Download or read book Structure and Function of Gangliosides written by Lars Svennerholm and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume records the proceedings of an International Symposium on The Structure and Function of Gangliosides, held at Le Bischenberg, Alsace, France, in April 23-27, 1979. The meeting was convened to get a comprehensive view of the immense activity that had occurred in the field since the previous conference on gangliosides held at Mont Sainte-Odile, ~lsace, France, in April 1973. At a conference on Enzymes of Lipid Metabolism held at the same place in April, 1977, several of the participants from the first ganglioside conference in 1973 met again. All previous participants agreed that the first meeting with its many frank and stimulating lectures, round tables and informal discussions had been of tremendous importance for the activity in the field and led to many personal contacts and a warm friendship among the ganglioside researchers. The success of the first meeting must be ascribed largely to one single man, PAUL MANDEL. Therefore, we decided to dedicate the next ganglioside conference to hirn and I was given the privilege to arrange the meeting together with him and staff members at Centre de Neurochirnie, Strasbourg. The Symposium on The Structure and Function of Gangliosides was arranged to honour PAUL MANDEL for his unique and never failing efforts to promote and strengthen international col laboration in all fields of neurochemistry.