Supramolecular Chemistry In Biomedical Imaging

Author : Stephen Faulkner
Publisher : Royal Society of Chemistry
ISBN 13 : 183916137X
Total Pages : 349 pages
Book Rating : 4.77/5 ( download)

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Download or read book Supramolecular Chemistry in Biomedical Imaging written by Stephen Faulkner and published by Royal Society of Chemistry. This book was released on 2022-04-01 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.

Author : Hans-Jorg Schneider
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737827
Total Pages : 550 pages
Book Rating : 4.21/5 ( download)

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Download or read book Supramolecular Systems in Biomedical Fields written by Hans-Jorg Schneider and published by Royal Society of Chemistry. This book was released on 2013-09-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.

Author : Peter J. Cragg
Publisher : Springer Science & Business Media
ISBN 13 : 9048125820
Total Pages : 267 pages
Book Rating : 4.21/5 ( download)

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Download or read book Supramolecular Chemistry written by Peter J. Cragg and published by Springer Science & Business Media. This book was released on 2010-08-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.

Author : L. Fabbrizzi
Publisher : Springer Science & Business Media
ISBN 13 : 9401583803
Total Pages : 445 pages
Book Rating : 4.00/5 ( download)

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Download or read book Transition Metals in Supramolecular Chemistry written by L. Fabbrizzi and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the pioneering publications on coordination chemistry by Lehn and Pedersen in the late 1960s, coupled with the more orthodox interest from the transition metal chemists on template reactions (Busch, 1964), the field of supramolecular chemistry has grown at an astonishing rate. The use of transition metals as essential constituents of multi-component assemblies has been especially sharp in recent years, since the metals are prone to quick and reversible redox changes, and there is a wide variety of metal--ligand interactions. Such properties make supramolecular complexes of transition metal ions suitable candidates for exploration as light--energy converters and signal processors. Transition Metals in Supramolecular Chemistry focuses on the following main topics: (1) metal controlled organization of novel molecular assemblies and shapes; (2) design of molecular switches and devices operating through metal centres; (3) supramolecular catalysts that mimic metalloenzymes; (4) metal-containing sensory reagents and supramolecular recognition; and (5) molecular materials that display powerful electronic, optoelectronic and magnetic properties.

Author : Omar Azzaroni
Publisher : John Wiley & Sons
ISBN 13 : 3527834052
Total Pages : 1801 pages
Book Rating : 4.51/5 ( download)

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Download or read book Supramolecular Nanotechnology written by Omar Azzaroni and published by John Wiley & Sons. This book was released on 2023-04-25 with total page 1801 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular Nanotechnology Provides up-to-date coverage of both current knowledge and new developments in the dynamic and interdisciplinary field of supramolecular nanotechnology In recent years, supramolecular nanotechnology has revolutionized research in chemistry, physics, and materials science. These easily manipulated molecular units enable the synthesis of novel nanomaterials for use in a wide range of current and potential applications including electronics, sensors, drug delivery, and imaging. Supramolecular Nanotechnology presents a state-of-the-art overview of functional self-assembling nanomaterials based on organic and polymeric molecules. Featuring contributions by an international panel of experts in the field, this comprehensive volume covers the design of self-assembled materials, their synthesis and diverse fabrication methods, the characterization of supramolecular architectures, and current and emerging applications in chemistry, biology, and medicine. Detailed chapters discuss the synthesis of peptide-based supramolecular structures and polymeric self-assembling materials, their characterization, advanced microscopy techniques, nanostructures made of porphyrins, polyelectrolytes, silica, their application in catalysis and cancer, atomistic and coarse-grained simulations, and more. Presents cutting-edge research on rationally designed, self-assembled supramolecular structures Discusses the impact of supramolecular nanotechnology on current and future research and technology Highlights applications of self-assembled supramolecular systems in catalysis, biomedical imaging, cancer therapies, and regenerative medicine Provides synthetic strategies for preparing the molecular assemblies and various characterization techniques for assessing the supramolecular morphology Describes theoretical modeling and simulation techniques for analyzing supramolecular nanostructures Supramolecular Nanotechnology: Advanced Design of Self-Assembled Functional Materials is essential reading for materials scientists and engineers, polymer and organic chemists, pharmaceutical scientists, molecular physicists and biologists, and chemical engineers.

Author : John Roy George Sander
Publisher :
ISBN 13 :
Total Pages : 201 pages
Book Rating : 4.97/5 ( download)

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Download or read book Expansions of Supramolecular Chemistry written by John Roy George Sander and published by . This book was released on 2012 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crystal engineering has matured into a design-driven field based on the exploitation of reliable interactions between the functional groups of molecules so as to achieve desired properties. The utility of crystal engineering has been realized in a breadth of fields and, as a microcosm of crystal engineering, this thesis will explore the application of crystal engineering in the pharmaceutical sciences, nanotechnology, synthetic chemistry, materials science, and biomedical imaging.

Author : Luling Wu
Publisher : Royal Society of Chemistry
ISBN 13 : 1839167335
Total Pages : 493 pages
Book Rating : 4.31/5 ( download)

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Download or read book Fluorescent Chemosensors written by Luling Wu and published by Royal Society of Chemistry. This book was released on 2023-04-14 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescent chemosensors have been widely applied in many diverse fields such as biology, physiology, pharmacology, and environmental sciences. The interdisciplinary nature of chemosensor research has continued to grow over the last 25 years to meet the increasing needs of monitoring our environment and health. More recently, a large range of fluorescent chemosensors have been established for the detection of biologically and/or environmentally important species, and are increasingly being used to solve biological problems. The use of these molecules as imaging probes to diagnose and treat disease is gaining momentum with clear future applications. This book will bring together world-leading experts to describe the current state of play in the field and introduce the cutting-edge research and possible future directions into fluorescent chemosensors design. Chapters focus on the basic principles involved in the design of chemosensors for specific analytes, problems, and challenges in the field. Concentrating on advanced techniques and methods, the book will be of use for academics and researchers across a number of disciplines, with international appeal.

Author : Jurriaan Huskens
Publisher : John Wiley & Sons
ISBN 13 : 1119143462
Total Pages : 434 pages
Book Rating : 4.68/5 ( download)

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Download or read book Multivalency written by Jurriaan Huskens and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.

Author : Kristin Bowman-James
Publisher : John Wiley & Sons
ISBN 13 : 3527639519
Total Pages : 644 pages
Book Rating : 4.19/5 ( download)

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Download or read book Anion Coordination Chemistry written by Kristin Bowman-James and published by John Wiley & Sons. This book was released on 2012-03-27 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the pioneering work in supramolecular chemistry from the last 20 years or so, this monograph addresses new and recent approaches to anion coordination chemistry. Synthesis of receptors, biological receptors and metallareceptors, the energetics of anion binding, molecular structures of anion complexes, sensing devices are presented and computational studies addressed to aid with the understanding of the different driving forces responsible for anion complexation. The reader is promised an actual picture of the state of the art for this exciting and constantly evolving field of supramolecular anion coordination chemistry. The topics range from ion channels to selective sensors, making it attractive to all researchers and PhD students with an interest in supramolecular chemistry.

Author : Hans-Jörg Schneider
Publisher : CRC Press
ISBN 13 : 1439840148
Total Pages : 457 pages
Book Rating : 4.46/5 ( download)

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Download or read book Applications of Supramolecular Chemistry written by Hans-Jörg Schneider and published by CRC Press. This book was released on 2012-03-28 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Supramolecular Chemistry introduces the use of non-covalent interactions and molecular recognition for many fields. Applications include the analysis of technically, medically, and environmentally important chemical compounds, their separation, purification and removal, and the design of new materials, including supramolecular electronics. The book also explores biological interactions and applications in the food and textile industries.