Structure Function Correlation On Rat Kidney

Author : Walter Pfaller
Publisher : Springer Science & Business Media
ISBN 13 : 3642682871
Total Pages : 183 pages
Book Rating : 4.72/5 ( download)

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Download or read book Structure Function Correlation on Rat Kidney written by Walter Pfaller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades an exceedingly large number of experimental and clinical investigations have been performed in an attempt to analyze the way in which the kidney functions. The basis for all this work was established during the nineteenth and the early twentieth century by morphologists (Bowman 1842; Hyrtl1863, 1872; Heidenhain 1874; Peter 1909; von Mollendorf 1930). All these investigators clearly outlined the extremely heterogeneous assembly of renal tissue and also defined the nephron as the smallest morphological unit. It was further the merit of these anato mists and histologists to preclude quite a number of nephron functions based merely on their careful observations. Contemporary histologists have been able to add little to these observations. Unfortunately with the introduction of physiologic in vivo et situ studies on kidneys the interest in heterogeneity waned. This lack of attention was aggravated by the introduction of the clearance techniques which cannot account for regional differences in the function of the smallest unit, the nephron. That ana tomic heterogeneity has a functional correlate was strongly suggested by Trueta et al. (1947) and vigorously stimulated a number of studies. The development of physiologic microtechniques, like micropuncture and microperfusion of single nephrons, or the perfusion of isolated nephron portions and electrophysiologic studies, enormously expanded our knowledge concerning details regarding nephron and total renal func tion.

Author : Walter Pfaller
Publisher :
ISBN 13 : 9783642682889
Total Pages : 122 pages
Book Rating : 4.8X/5 ( download)

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Download or read book Structure Function Correlation on Rat Kidney written by Walter Pfaller and published by . This book was released on 1981-12 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Agnes Antoinette Marie Gribnau
Publisher :
ISBN 13 : 9780387104690
Total Pages : 106 pages
Book Rating : 4.90/5 ( download)

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Download or read book Structure Function Correlation on Rat Kidney written by Agnes Antoinette Marie Gribnau and published by . This book was released on 1981 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : G. A. Zweers
Publisher :
ISBN 13 : 9780387110745
Total Pages : 107 pages
Book Rating : 4.47/5 ( download)

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Download or read book Structure Function Correlation on Rat Kidney written by G. A. Zweers and published by . This book was released on 1982 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Andrew DeWitt Baines
Publisher :
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.24/5 ( download)

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Download or read book A Correlation of Structure, Function and Enzyme Activity in Regenerating Kidney Tubules written by Andrew DeWitt Baines and published by . This book was released on 1965 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Thomas C. Jones
Publisher : Springer Science & Business Media
ISBN 13 : 3642803350
Total Pages : 496 pages
Book Rating : 4.52/5 ( download)

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Download or read book Urinary System written by Thomas C. Jones and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete update on the safety testing of foods, drugs, and chemicals in laboratory animals, featuring: - a thorough review of each subject area with extensive revision in line with new information and concepts - electron micrographs in exquisite detail to illustrate results of recent research - the effects of many carcinogens described succinctly and illustrated in detail - neoplasms described in detail and compared with natural and induced tumours in other species - standardised nomenclature. Of interest to those interested in the many applications to human patients, Urinary System: - facilitates uniform interpretation of bioassay results world-wide - provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures of the kidneys - explains the functional significance of details by identifying the composition of structures at the molecular level. Forming a solid basis for understanding the causes and effects of disease of the urinary system, this is essential reading for pathologists, toxicologists, regulatory agencies, and all those involved in carcinogenicity and toxicity studies.

Author : Ulla C. Kopp
Publisher : Biota Publishing
ISBN 13 : 161504776X
Total Pages : 122 pages
Book Rating : 4.65/5 ( download)

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Download or read book Neural Control of Renal Function, Second Edition written by Ulla C. Kopp and published by Biota Publishing. This book was released on 2018-07-17 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.

Author : Rudolfs K. Zalups
Publisher : CRC Press
ISBN 13 : 9781439805602
Total Pages : 462 pages
Book Rating : 4.01/5 ( download)

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Download or read book Methods in Renal Toxicology written by Rudolfs K. Zalups and published by CRC Press. This book was released on 1996-03-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only up-to-date compilation of renal methods available, this book is the definitive resource for any renal researcher eager to stay ahead. Methods in Renal Toxicology presents a vast array of methods for the study of renal cellular and tubular structure, function, and biochemistry under physiological, toxicological, and pathological conditions. It provides detailed descriptions in easy-to-understand language of methods designed to enhance your research efforts. Methods in Renal Toxicology puts you on the cutting edge with valuable chapters detailing molecular methods and transgene and gene targeting - the most recent approaches to the study of renal toxicology. Overall, the book's topics range from non-invasive assessments of renal function in the whole animal and clinical settings to cellular and molecular approaches. Specifically, the book delves into measurements of clearance and urinary markers, histopathology, and methods to assess renal carcinogenesis, mutagenesis, oxidative stress, mitochondria injury, cellular repair, and drug metabolism and transport. A variety of in vitro methods are also described, including the isolated perfused kidney, micropuncture, microperfusion, microdissection, renal slices, isolated perfused tubules, suspensions of tubules and isolated cells, and primary cell cultures and cell lines. Methods in Renal Toxicology is a must-have resource for all renal investigators. Nowhere else can you find concise descriptions of traditional and up-to-the-minute renal toxicology methods in such a practical, well-written single-volume guide.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309172810
Total Pages : 448 pages
Book Rating : 4.13/5 ( download)

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Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.

Author : B. D. Ross
Publisher : Elsevier
ISBN 13 : 1483182282
Total Pages : 367 pages
Book Rating : 4.85/5 ( download)

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Download or read book Biochemical Aspects of Renal Function written by B. D. Ross and published by Elsevier. This book was released on 2013-09-17 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Aspects of Renal Function is a collection of papers from the Fifth International Symposium on the Biochemical Aspects of Renal Function. The materials presented details the advancement in the understanding of various areas in the biochemistry of renal function. The title first covers the metabolic studies in kidney, and then proceeds to tackling intermediary metabolism and its regulation. Next, the selection discusses the biochemistry of filtration and reabsorption. The last chapter covers renal work and ATP. The book will be of great interest to students, researchers, and practitioners of medicine, biochemistry, and physiological sciences.