Snp

Author : Anton A. Komar
Publisher : Humana Press
ISBN 13 : 9781617796791
Total Pages : 464 pages
Book Rating : 4.94/5 ( download)

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Download or read book Single Nucleotide Polymorphisms written by Anton A. Komar and published by Humana Press. This book was released on 2012-02-25 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field.

Author : James Mitchell
Publisher : Biteback Publishing
ISBN 13 : 1785901230
Total Pages : 324 pages
Book Rating : 4.32/5 ( download)

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Download or read book Scottish National Party (SNP) Leaders written by James Mitchell and published by Biteback Publishing. This book was released on 2016-09-15 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: By any measure, the story of the Scottish National Party is an extraordinary one. Forced to endure decades of electoral irrelevance since its creation in the 1930s, during which it often found itself grappling with internal debate on strategy, and rebellion from within its own ranks, the SNP virtually swept the board in the 2015 general election, winning all but three of Scotland's fifty-nine seats in Westminster. What's more, under the current leadership of Nicola Sturgeon, the SNP has never been a more important force in the landscape of British politics. The leaders who have stood at its helm during this tumultuous eighty-year history - from Sir Alexander MacEwen to Nicola Sturgeon and Alex Salmond - have steered the SNP vessel with varying degrees of success, but there is no doubt that all have contributed to the shape, purpose and ultimate goal of the party of government we see today. The latest addition to the acclaimed British Political Leaders series, Scottish National Party Leaders examines each of these senior figures for the first time, and is essential reading for anyone curious about how this former fringe party evolved into a political phenomenon, changing not only the face of Scottish politics, but British politics as well.

Author : Pui-Yan Kwok
Publisher : Springer Science & Business Media
ISBN 13 : 1592593275
Total Pages : 276 pages
Book Rating : 4.79/5 ( download)

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Download or read book Single Nucleotide Polymorphisms written by Pui-Yan Kwok and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.

Author : Nnadozie C. Oraguzie
Publisher : Springer Science & Business Media
ISBN 13 : 0387360115
Total Pages : 290 pages
Book Rating : 4.19/5 ( download)

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Download or read book Association Mapping in Plants written by Nnadozie C. Oraguzie and published by Springer Science & Business Media. This book was released on 2007-01-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.

Author : Gerry Hassan
Publisher : Edinburgh University Press
ISBN 13 : 0748642110
Total Pages : 240 pages
Book Rating : 4.13/5 ( download)

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Download or read book Modern SNP written by Gerry Hassan and published by Edinburgh University Press. This book was released on 2009-10-05 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Scottish National Party has played a significant role in the politics of Scotland in the last forty years. In particular it has contributed to and shaped the impact and dynamics of devolution. This collection brings together academics, writers, commentators and analysts of Scottish politics to address the nature of the SNP: its position in Scotland, its influence on devolution, its role as a minority administration and its relationship with other institutions in Scotland, the UK and Europe.

Author : Peter A. Lynch
Publisher :
ISBN 13 : 9781860570575
Total Pages : 0 pages
Book Rating : 4.77/5 ( download)

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Download or read book SNP written by Peter A. Lynch and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though the SNP has existed since 1934, no full-length history of the Scottish National Party was written until the first edition of this book in 2002. With the SNP having governed Scotland since 2007, and with an outright majority since 2011, the long-held SNP policy of an Independence Referendum is now a reality and scheduled to be held in 2014.

Author : Robert Johns
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.01/5 ( download)

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Download or read book Takeover written by Robert Johns and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : David Torrance
Publisher : Casemate Publishers
ISBN 13 : 0857908464
Total Pages : 339 pages
Book Rating : 4.69/5 ( download)

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Download or read book Nicola Sturgeon written by David Torrance and published by Casemate Publishers. This book was released on 2015-03-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biography of the Scottish leader by an author with “an excellent eye for political detail” (Scotland on Sunday). Nicola Sturgeon became involved in politics as a teenager, and then began a law career in Glasgow. She would go on to become Scotland’s youngest parliamentary candidate in 1992, in her early twenties. Considered a rising star, she eventually reached the pinnacle of Scottish government as First Minister and leader of the Scottish National Party—the party she’d joined at the age of sixteen. This book explores her reputation for efficiency and shrewd political judgment, her family life, and her role in the country’s turbulent recent years with the campaign for Scottish independence from the United Kingdom and the Brexit vote. It is a portrait of a fascinating woman as well as an “illuminating appraisal” of her impressive career (Spectator).

Author : Sukanta Mondal
Publisher : Academic Press
ISBN 13 : 0128206128
Total Pages : 340 pages
Book Rating : 4.26/5 ( download)

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Download or read book Advances in Animal Genomics written by Sukanta Mondal and published by Academic Press. This book was released on 2020-11-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. Integrates basic and advanced concepts of animal biotechnology and presents future developments Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion

Author : Sebastian Wernicke
Publisher : diplom.de
ISBN 13 : 3832474811
Total Pages : 138 pages
Book Rating : 4.12/5 ( download)

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Download or read book On the Algorithmic Tractability of Single Nucleotide Polymorphism (SNP) Analysis and Related Problems written by Sebastian Wernicke and published by diplom.de. This book was released on 2014-04-02 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaltsangabe:Abstract: This work brings together two areas of science biology and informatics that have only recently been connected in the emerging (and vastly growing) research field of Bioinformatics. In order to achieve a common basis for Parts 2 and 3 of this work, Part 1 intends to introduce the computer scientist to the relevant biological background and terminology (Chapter 2), and to familiarize the biologist with the relevant topics from theoretical computer science (Chapter 3). Chapter 2 first introduces some terminology from the field of genetics, thereby defining SNPs. We then motivate the analysis of SNPs by two applications, i.e. the analysis of evolutionary development and the field of pharmacogenetics. Especially the field of pharmacogenetics is capable of having an enormous impact on medicine and the pharmaceutical industry in the near future by using SNP data to predict the efficacy of medication. Chapter 3 gives a brief introduction to the field of computational complexity. We will see and motivate how algorithms are analyzed in theoretical computer science. This will lead to the definition of complexity classes , introducing the class NP which includes computationally hard problems. Some of the hard problems in the class NP can be solved efficiently using the tool of fixed-parameter tractability, introduced at the end of this chapter. An important application of SNP data is in the analysis of the evolutionary history of species development (phylogenetic analysis part two chapters 4 and 5). As will be made plausible in Chapter 5 using SNP data is in many ways superior to previous approaches of phylogenetic analysis. In order to analyze the development of species using SNP data, an underlying model of evolution must be specified. A popular model is the so-called perfect phylogeny, but the construction of this phylogeny is a computationally hard problem when there are inconsistencies (such as read-errors or an imperfect .t to the model of perfect phylogeny) in the underlying data. Chapter 4 analyzes the problem of forbidden submatrix removal which is closely connected to constructing perfect phylogenies we will see in Chapter 5 that its computational complexity is directly related to that of constructing a perfect phylogeny from data which is partially erroneous. In this chapter, we analyze the algorithmic tractability of forbidden submatrix removal , characterizing cases where this problem is NP-complete (being [...]