Selected Papers Of Frederick Sanger

Author : Frederick Sanger
Publisher : World Scientific
ISBN 13 : 9789810224301
Total Pages : 680 pages
Book Rating : 4.03/5 ( download)

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Download or read book Selected Papers of Frederick Sanger written by Frederick Sanger and published by World Scientific. This book was released on 1996 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume is mainly concerned with the development of methods for ?sequencing? ? that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.

Author : Joe S. Jeffers
Publisher : Springer
ISBN 13 : 3319547097
Total Pages : 88 pages
Book Rating : 4.91/5 ( download)

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Download or read book Frederick Sanger written by Joe S. Jeffers and published by Springer. This book was released on 2017-03-14 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.

Author : George G. Brownlee
Publisher : Cambridge University Press
ISBN 13 : 1316124053
Total Pages : 315 pages
Book Rating : 4.55/5 ( download)

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Download or read book Fred Sanger - Double Nobel Laureate written by George G. Brownlee and published by Cambridge University Press. This book was released on 2020-04-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.

Author : H Gobind Khorana
Publisher : World Scientific
ISBN 13 : 9814496650
Total Pages : 633 pages
Book Rating : 4.50/5 ( download)

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Download or read book Chemical Biology, Selected Papers Of H G Khorana (With Introductions) written by H Gobind Khorana and published by World Scientific. This book was released on 2000-05-24 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two chapters of this invaluable book trace the developments of the chemistry and macromolecular structures, respectively, of proteins and nuclei acids. Similarly, the introductions to the succeeding chapters review, step by step, the historical landmarks in the topics covered. These include discoveries of biological phosphate esters, nucleotides and nucleotide coenzymes (important in intermediary metabolism), the nature of the genetic material and biological synthesis of proteins, formulation of the problem of the genetic code, and perspectives on bioenergetics.The selected papers illustrate the developments of the chemical synthesis of nucleotides and nucleotide coenzymes of ribo- and deoxy-ribo-polynucleotides (RNA, DNA), of the total synthesis of genes in the laboratory, and principles for gene amplification (PCR). Another major section covers studies of enzymes that degrade nucleic acids, the structure of transfer RNA and its role in protein synthesis, and the author's work on the elucidation of the genetic code. Finally, there are descriptions of the studies on biological membranes and the membrane protein bacteriorhodopsin, a biological proton pump. These studies elucidated the mechanism of proton translocation, which is central to bioenergetics.

Author :
Publisher :
ISBN 13 :
Total Pages : 1332 pages
Book Rating : 4.36/5 ( download)

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Download or read book International Books in Print written by and published by . This book was released on 1998 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Ulrich Hubscher
Publisher : World Scientific
ISBN 13 : 9814465453
Total Pages : 338 pages
Book Rating : 4.58/5 ( download)

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Download or read book Dna Polymerases: Discovery, Characterization And Functions In Cellular Dna Transactions written by Ulrich Hubscher and published by World Scientific. This book was released on 2010-04-14 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.

Author : Michael Bliss
Publisher : University of Toronto Press
ISBN 13 : 1487516746
Total Pages : 320 pages
Book Rating : 4.41/5 ( download)

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Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Author : Rose Arny
Publisher :
ISBN 13 :
Total Pages : 1752 pages
Book Rating : 4.84/5 ( download)

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Download or read book Forthcoming Books written by Rose Arny and published by . This book was released on 2002 with total page 1752 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.35/5 ( download)

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Download or read book Bulletin of the Atomic Scientists written by and published by . This book was released on 2008 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : G K HALL
Publisher : Macmillan Reference USA
ISBN 13 : 9780783817552
Total Pages : 672 pages
Book Rating : 4.5X/5 ( download)

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Download or read book Bibliographic Guide to East Asian Studies 1996 written by G K HALL and published by Macmillan Reference USA. This book was released on 1997-07 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: