Rna The Epicenter Of Genetic Information

Author : John Mattick
Publisher : CRC Press
ISBN 13 : 1000623114
Total Pages : 879 pages
Book Rating : 4.16/5 ( download)

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Download or read book RNA, the Epicenter of Genetic Information written by John Mattick and published by CRC Press. This book was released on 2022-09-20 with total page 879 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

Author : Edited by T. M. Jefferson
Publisher :
ISBN 13 : 9781533541840
Total Pages : 506 pages
Book Rating : 4.41/5 ( download)

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Download or read book RNA - a Genetic Messenger written by Edited by T. M. Jefferson and published by . This book was released on 2016-05-30 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribonucleic acid (RNA) is a polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes. RNA and DNA are nucleic acids, and, along with proteins and carbohydrates, constitute the three major macromolecules essential for all known forms of life. Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA it is more often found in nature as a single-strand folded onto itself, rather than a paired double-strand. Cellular organisms use messenger RNA (mRNA) to convey genetic information (using the letters G, U, A, and C to denote the nitrogenous bases guanine, uracil, adenine, and cytosine) that directs synthesis of specific proteins. Many viruses encode their genetic information using an RNA genome.Some RNA molecules play an active role within cells by catalyzing biological reactions, controlling gene expression, or sensing and communicating responses to cellular signals. One of these active processes is protein synthesis, a universal function wherein mRNA molecules direct the assembly of proteins on ribosomes. This process uses transfer RNA (tRNA) molecules to deliver amino acids to the ribosome, where ribosomal RNA (rRNA) then links amino acids together to form proteins.This book gives a comprehensive overview of the various functions of RNA.

Author : Henrik Nielsen
Publisher : Humana Press
ISBN 13 : 9781588299130
Total Pages : 0 pages
Book Rating : 4.39/5 ( download)

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Download or read book RNA written by Henrik Nielsen and published by Humana Press. This book was released on 2010-12-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent insight into the transcripts generated from the mammalian genome (i.e. the transcriptome) has revealed that transcription is a far more complex phenomenon than previously thought. In RNA: Methods and Protocols, expert researchers provide the procedures and methods used to describe the structure of messenger RNAs and non-coding RNAs that are transcribed by RNA polymerase II as the immediate gene products in mammalian cells. Focused on the structure of the RNA products of “gene X” and the mapping of proteins associated with these RNAs, the volume presents appropriate information for non-specialists in RNA biology. Written in the highly successful Methods in Molecular BiologyTM series format, many chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, RNA: Methods and Protocols views the transcriptional landscape with an appreciation for the role that proteins play in the processing and interpretation of genetic information in an attempt to further our crucial knowledge of the many products and sophisticated regulatory networks that result from it.

Author : Jenny Chen
Publisher : Cavendish Square Publishing, LLC
ISBN 13 : 1502619563
Total Pages : 130 pages
Book Rating : 4.63/5 ( download)

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Download or read book DNA and RNA written by Jenny Chen and published by Cavendish Square Publishing, LLC. This book was released on 2016-07-15 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA and RNA explores Friedrich Miescher's major scientific discovery in 1944 when he isolated DNA for the first time, forever changing our understanding of the building blocks of the human body. The book looks at Miescher's path to isolating DNA and the ways that his work influenced James Watson and Francis Crick, who discovered the double helix in 1957. DNA and RNA describes the many ways that these discoveries are relevant to our lives, as well as the numerous ethical implications of the discoveries.

Author : Maria Szekely
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.1U/5 ( download)

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Download or read book From DNA to Protein written by Maria Szekely and published by John Wiley & Sons. This book was released on 1980 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : James E. Darnell
Publisher :
ISBN 13 : 9781936113194
Total Pages : 0 pages
Book Rating : 4.98/5 ( download)

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Download or read book RNA written by James E. Darnell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules could function as catalysts. --

Author : Gunter Meister
Publisher : Wiley-VCH
ISBN 13 : 9783527322787
Total Pages : 0 pages
Book Rating : 4.87/5 ( download)

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Download or read book RNA Biology written by Gunter Meister and published by Wiley-VCH. This book was released on 2011-05-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998. Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope. The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.

Author : Lee B. Kass
Publisher : CRC Press
ISBN 13 : 104003215X
Total Pages : 411 pages
Book Rating : 4.52/5 ( download)

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Download or read book From Chromosomes to Mobile Genetic Elements written by Lee B. Kass and published by CRC Press. This book was released on 2024-06-27 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This biography of Nobel Laureate Barbara McClintock (1902-1992) places her life and work in its social, scientific and personal context. The author examines the development of Barbara McClintock’s scientific work and her influence upon individuals and upon the fields of cytogenetics and evolutionary biology in the period from 1902 to the present. The history documents years of McClintock’s notable and lauded scientific work long before she discovered and named transposable elements in the mid-1940s for which she ultimately received the Nobel Prize. The biography employs documented evidence to expose, demystify, and provide clarity for legends and misinterpretations of McClintock’s life and work. Key Features Exposes and demystifies myths and legends told about McClintock’s time in Missouri Clarifies the changing language of genes and genetics Places in perspective the history of McClintock’s research Documents McClintock’s family and early life before college Provides documented details of McClintock’s time in Nazi Germany

Author : David Elliott
Publisher : Oxford University Press
ISBN 13 : 019107103X
Total Pages : 445 pages
Book Rating : 4.34/5 ( download)

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Download or read book Molecular Biology of RNA written by David Elliott and published by Oxford University Press. This book was released on 2017-01-31 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

Author : Jan Barciszewski
Publisher : Springer Nature
ISBN 13 : 3031363906
Total Pages : 662 pages
Book Rating : 4.00/5 ( download)

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Download or read book RNA Structure and Function written by Jan Barciszewski and published by Springer Nature. This book was released on 2023-12-05 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved. RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine. In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases. This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry.