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Author : Giovanni Nigita
Publisher : Frontiers Media SA
ISBN 13 : 2832527779
Total Pages : 208 pages
Book Rating : 4.71/5 ( download)
Download or read book RNA modifications and epitranscriptomics - volume II written by Giovanni Nigita and published by Frontiers Media SA. This book was released on 2023-06-30 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stefan Jurga
Publisher : Springer Nature
ISBN 13 : 3030716120
Total Pages : 632 pages
Book Rating : 4.27/5 ( download)
Download or read book Epitranscriptomics written by Stefan Jurga and published by Springer Nature. This book was released on 2021-07-28 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Author : Mary McMahon
Publisher : Humana
ISBN 13 : 9781071613764
Total Pages : 427 pages
Book Rating : 4.66/5 ( download)
Download or read book RNA Modifications written by Mary McMahon and published by Humana. This book was released on 2022-06-18 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. /divChapter 20 is available open access under a CC BY 4.0 license.
Author : Mattia Pelizzola
Publisher : Frontiers Media SA
ISBN 13 : 2889664406
Total Pages : 155 pages
Book Rating : 4.05/5 ( download)
Download or read book Computational Epitranscriptomics: Bioinformatic Approaches for the Analysis of RNA Modifications written by Mattia Pelizzola and published by Frontiers Media SA. This book was released on 2021-02-02 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xiao Han
Publisher : Frontiers Media SA
ISBN 13 : 2889761061
Total Pages : 387 pages
Book Rating : 4.67/5 ( download)
Download or read book RNA Modifications and Epitranscriptomics written by Xiao Han and published by Frontiers Media SA. This book was released on 2022-05-05 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giovanni Nigita
Publisher : Frontiers Media SA
ISBN 13 : 2889457419
Total Pages : 127 pages
Book Rating : 4.10/5 ( download)
Download or read book Epitranscriptomics: The Novel RNA Frontier written by Giovanni Nigita and published by Frontiers Media SA. This book was released on 2019-01-31 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the formulation of the central dogma of molecular biology and the later discovery of classes of non-coding RNAs, the primary focus of Genetics was essentially on variation of DNA aiming at elucidating biological pathways perturbed in diseases. Recently, extensive attention has shifted towards the study of posttranscriptional RNA modifications occurring in both protein-coding as well as non-coding RNAs, revealing a novel and finer layer of complexity in gene regulation. This, in turn, has led to the birth of the novel field of ‘Epitranscriptomics’. The recent increase of applications of high-throughput sequencing technology (HTS) has allowed the unprecedented opportunity to identify on a transcriptome-wide scale, millions of RNA modifications in human genes, counting today more than 140 distinct types such as: methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe) methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe), pseudourylation (?), deamination (e.g. A-to-I RNA editing). The scope of this Research Topic was to collect both reviews and research articles addressing the wet lab approaches and bioinformatics methodologies necessary to aid in the identification of novel RNA modifications and characterization of their biological functions. Among the articles embracing the aim of the Research Topic, we have collected four original research and methods articles, five reviews, and a technology article.
Author : Narendra Wajapeyee
Publisher :
ISBN 13 : 9781493988082
Total Pages : 298 pages
Book Rating : 4.85/5 ( download)
Download or read book Epitranscriptomics written by Narendra Wajapeyee and published by . This book was released on 2018 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128023317
Total Pages : 441 pages
Book Rating : 4.10/5 ( download)
Download or read book RNA Modification written by and published by Academic Press. This book was released on 2015-12-11 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA Modification provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and protocols available today. Dynamic RNA modifications and their roles in biological regulation are the current frontier of life science research This volume of Methods in Enzymology represents up to date knowledge and protocols
Author : Mary McMahon
Publisher :
ISBN 13 : 9781071613740
Total Pages : 427 pages
Book Rating : 4.4X/5 ( download)
Download or read book RNA Modifications written by Mary McMahon and published by . This book was released on 2021 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. Chapter 20 is available open access under a CC BY 4.0 license.
Author :
Publisher :
ISBN 13 :
Total Pages : 409 pages
Book Rating : 4.51/5 ( download)
Download or read book RNA Modification written by and published by . This book was released on 2015 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt:
