Regulatory Rnas

Author : Bibekanand Mallick
Publisher : Springer Science & Business Media
ISBN 13 : 3642225160
Total Pages : 549 pages
Book Rating : 4.61/5 ( download)

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Download or read book Regulatory RNAs written by Bibekanand Mallick and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also increasingly clear that these play critical roles in gene regulatory processes during development and differentiation. Further, regulatory RNAs are useful biomarkers for diagnosis of diseases. Hence these RNA regulators are essential to the development of therapeutics. This book on “Regulatory RNAs” offers a comprehensive view on our current understanding of these regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding RNA, small RNA etc. It addresses both the biogenesis and mechanism of action of regulatory RNAs with a primary focus on their annotation, experimental methodologies (microarray, next-gen sequencing etc.) for their discovery, computational tools for their prediction, and above all, applications of these revolutionary regulatory molecules in understanding biological systems and diseases, including therapeutics. This comprehensive volume is intended for readers with research or teaching interests in ncRNA biology and will provide a major information resource on current research in the fast-moving fields of RNA and gene expression regulation. Cutting-edge and concise, “Regulatory RNAs: Basics, Methods and Applications” promises to support vital research in the field of regulatory RNAs, ever-continuing to grow rapidly and gain increasing importance in basic and translational biology.

Author :
Publisher : Academic Press
ISBN 13 : 0128171944
Total Pages : 444 pages
Book Rating : 4.43/5 ( download)

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Download or read book RNA-Based Regulation in Human Health and Disease written by and published by Academic Press. This book was released on 2020-08-19 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field

Author : Wolfgang Nellen
Publisher : Springer Science & Business Media
ISBN 13 : 3540742700
Total Pages : 16 pages
Book Rating : 4.08/5 ( download)

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Download or read book Small RNAs: written by Wolfgang Nellen and published by Springer Science & Business Media. This book was released on 2007-11-10 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the discovery of functional small RNAs has brought about an unprecedented revolution within the field of molecular biology. This volume describes strategies for the discovery and validation of small RNAs. It provides a snapshot of our current understanding of the different mechanisms triggered by small RNAs and the variations encountered in different organisms.

Author : Bruce Stillman
Publisher : CSHL Press
ISBN 13 : 0879698187
Total Pages : 577 pages
Book Rating : 4.88/5 ( download)

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Download or read book Regulatory RNAs written by Bruce Stillman and published by CSHL Press. This book was released on 2006 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores how the application of RNA technologies, combined with a growing understanding of the molecular basis of many RNA processes, is yielding new insights into the treatment of many human diseases.

Author : Anita Marchfelder
Publisher : Springer Science & Business Media
ISBN 13 : 3709102189
Total Pages : 263 pages
Book Rating : 4.83/5 ( download)

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Download or read book Regulatory RNAs in Prokaryotes written by Anita Marchfelder and published by Springer Science & Business Media. This book was released on 2012-12-23 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.

Author : Rajesh K. Gaur
Publisher : CRC Press
ISBN 13 : 1420008706
Total Pages : 440 pages
Book Rating : 4.08/5 ( download)

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Download or read book Regulation of Gene Expression by Small RNAs written by Rajesh K. Gaur and published by CRC Press. This book was released on 2009-04-27 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p

Author : Xiao Li
Publisher : Frontiers Media SA
ISBN 13 : 2889717402
Total Pages : 126 pages
Book Rating : 4.08/5 ( download)

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Download or read book Regulatory RNAs in the Nucleus written by Xiao Li and published by Frontiers Media SA. This book was released on 2021-11-30 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editors Xiao Li, Bing Zhou, and Wenbo Li hold patents related to the Research Topic subject. All other Topic Editors declare no competing interests.

Author : Anita Marchfelder
Publisher : Springer
ISBN 13 : 9783709102190
Total Pages : 258 pages
Book Rating : 4.97/5 ( download)

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Download or read book Regulatory RNAs in Prokaryotes written by Anita Marchfelder and published by Springer. This book was released on 2015-04-20 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date collection of review articles focusing on RNA-mediated regulation in prokaryotes. The various modes of action include the direct interaction with proteins, direct sensing of metabolites or of physical parameters, and the interaction with RNAs to stimulate or prevent binding of ribosomes or to stimulate degradation. Written by leading experts in the field, the book covers small RNA functions, RNA thermometers, riboswitches, the diversity of small RNA-guided CRISPR-Cas defense systems and selected RNA chaperons in both prokaryotic domains, bacteria and archaea. Recent advances towards the computational identification of regulatory RNAs and their targets are included and particular attention is paid to small RNA in pathogenic bacteria. This volume is the only one exclusively covering regulatory RNAs in the prokaryotic domains to date, making it essential literature for anyone interested in RNA function and gene regulation and a valuable resource for teaching these concepts.

Author : Thomas Dandekar
Publisher : Springer Science & Business Media
ISBN 13 : 3642979939
Total Pages : 270 pages
Book Rating : 4.34/5 ( download)

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Download or read book Regulatory RNA written by Thomas Dandekar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to and an overview of the field of regulatory RNA, focusing on the identification of regulatory elements and motifs in such RNA molecules. Central to the book is the use of appropriate techniques to identify regulatory RNA and regulatory motifs. The prospects for this new and expanding research field - understanding regulatory RNA elements and motifs - are also explored, including new developments, medical applications, and applications in other fields.

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: