Regenerative Medicine And Stem Cell Therapy For The Eye

Author : Brian G. Ballios
Publisher : Springer
ISBN 13 : 3319980807
Total Pages : 212 pages
Book Rating : 4.05/5 ( download)

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Download or read book Regenerative Medicine and Stem Cell Therapy for the Eye written by Brian G. Ballios and published by Springer. This book was released on 2019-02-18 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease

Author : Brian G. Ballios
Publisher :
ISBN 13 : 9783319980812
Total Pages : 212 pages
Book Rating : 4.15/5 ( download)

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Download or read book Regenerative Medicine and Stem Cell Therapy for the Eye written by Brian G. Ballios and published by . This book was released on 2018 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease.

Author : Stephen Tsang
Publisher : Springer Science & Business Media
ISBN 13 : 146145493X
Total Pages : 196 pages
Book Rating : 4.39/5 ( download)

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Download or read book Stem Cell Biology and Regenerative Medicine in Ophthalmology written by Stephen Tsang and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.

Author : Alice Pébay
Publisher : Springer
ISBN 13 : 1493907875
Total Pages : 310 pages
Book Rating : 4.78/5 ( download)

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Download or read book Regenerative Biology of the Eye written by Alice Pébay and published by Springer. This book was released on 2014-05-23 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.

Author : R.P. Casaroli-Marano
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318025852
Total Pages : 220 pages
Book Rating : 4.59/5 ( download)

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Download or read book Cell-Based Therapy for Retinal Degenerative Disease written by R.P. Casaroli-Marano and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.

Author : Kapil Bharti
Publisher : Springer Nature
ISBN 13 : 3030284719
Total Pages : 201 pages
Book Rating : 4.18/5 ( download)

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Download or read book Pluripotent Stem Cells in Eye Disease Therapy written by Kapil Bharti and published by Springer Nature. This book was released on 2019-10-25 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases.

Author : Traian Chirila
Publisher : Elsevier
ISBN 13 : 184569743X
Total Pages : 565 pages
Book Rating : 4.33/5 ( download)

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Download or read book Biomaterials and Regenerative Medicine in Ophthalmology written by Traian Chirila and published by Elsevier. This book was released on 2009-12-18 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.20/5 ( download)

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Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : Alexander Battler
Publisher : Springer Science & Business Media
ISBN 13 : 9781846286766
Total Pages : 460 pages
Book Rating : 4.6X/5 ( download)

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Download or read book Stem Cell and Gene-Based Therapy written by Alexander Battler and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Author : Marco A. Zarbin
Publisher : Springer
ISBN 13 : 3030052222
Total Pages : 280 pages
Book Rating : 4.25/5 ( download)

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Download or read book Cell-Based Therapy for Degenerative Retinal Disease written by Marco A. Zarbin and published by Springer. This book was released on 2019-03-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.