Recombinant Growth

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Publisher :
ISBN 13 :
Total Pages : 38 pages
Book Rating : 4.24/5 ( download)

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Book Synopsis Recombinant Growth by : Martin L. Weitzman

Download or read book Recombinant Growth written by Martin L. Weitzman and published by . This book was released on 1996 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Growth Hormone

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Publisher : Springer Science & Business Media
ISBN 13 : 1461572010
Total Pages : 642 pages
Book Rating : 4.15/5 ( download)

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Book Synopsis Human Growth Hormone by : S. Raiti

Download or read book Human Growth Hormone written by S. Raiti and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been ten years since the National Hormone and Pituitary Program (then called the National Pituitary Agency) sponsored a symposium on human growth hormone (hGH). Numerous advances have occurred during this period. This book does not attempt to summarize past achievements. Rather, it deals with the contemporary issues in hGH research. A discussion of the present state of the art, of necessity, includes a review of the past. Some of the topics herein discussed include the following: 1. Growth hormone releasing factor (GRF). In 1973, the growth hormone inhibitory factor (somatostatin) had recently been discovered. The search for a releasing factor in humans led to its discovery not in the pituitary but in a pancreatic tumor that secreted growth hormone. The advances are discussed in this book. The current hope is that GRF will eventually become an effective therapeutic agent for idiopathic hypopituitarism in childhood and adolescence. 2. Biosynthesis of hGR by recombinant DNA technology. Current advances are discussed. Although hGH is not yet an approved drug, it will eventually become one. This will broaden our horizons in terms of hGH effectiveness in disorders other than hypopituitary dwarfism. The current experience with this type of hGH in both the Vnited States and Europe is reviewed by several authors.

Recombinant Protein Production in Yeast

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Publisher : Humana Press
ISBN 13 : 9781493958719
Total Pages : 262 pages
Book Rating : 4.12/5 ( download)

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Book Synopsis Recombinant Protein Production in Yeast by : Roslyn M. Bill

Download or read book Recombinant Protein Production in Yeast written by Roslyn M. Bill and published by Humana Press. This book was released on 2016-05-01 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews preparation of expression vectors, generation of high-yielding clones, scale-up, disruption of yeast cells to enable isolation of recombinant protein prior to purification and more, in the popular Methods in Molecular Biology format."

Recombinant DNA Products

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Publisher : CRC Press
ISBN 13 : 1351093150
Total Pages : 399 pages
Book Rating : 4.56/5 ( download)

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Book Synopsis Recombinant DNA Products by : Arthur P. Bollon

Download or read book Recombinant DNA Products written by Arthur P. Bollon and published by CRC Press. This book was released on 2018-01-18 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews advances made in recombinant DNA technology as it relates to the techniques employed, and the production and testing of potentially important products such as human interferon, insulin, and growth hormone.

Production of Recombinant Proteins

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Publisher : John Wiley & Sons
ISBN 13 : 3527604413
Total Pages : 429 pages
Book Rating : 4.18/5 ( download)

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Book Synopsis Production of Recombinant Proteins by : Gerd Gellissen

Download or read book Production of Recombinant Proteins written by Gerd Gellissen and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the choices of microbial and eukaryotic expression systems for production of recombinant proteins are many, most researchers in academic and industrial settings do not have ready access to pertinent biological and technical information since it is normally scattered throughout the scientific literature. This book closes the gap by providing information on the general biology of the host organism, a description of the expression platform, a methodological section -- with strains, genetic elements, vectors and special methods, where applicable -- as well as examples of proteins produced with the respective platform. The systems thus described are well balanced by the inclusion of three prokaryotes (two Gram-negatives and one Gram-positive), four yeasts, two filamentous fungi and two higher eukaryotic cell systems -- mammalian and plant cells. Throughout, the book provides valuable practical and theoretical information on the criteria and schemes for selecting the appropriate expression platform, the possibility and practicality of a universal expression vector, and on comparative industrial-scale fermentation, with the production of a recombinant Hepatitis B vaccine chosen as an industrial example. With a foreword by Herbert P. Schweizer, Colorado State University, USA: "As a whole, this book is a valuable and overdue resource for a varied audience. It is a practical guide for academic and industrial researchers who are confronted with the design of the most suitable expression platform for their favorite protein for technical or pharmaceutical purposes. In addition, the book is also a valuable study resource for professors and students in the fields of applied biology and biotechnology."

Recombinant Gene Expression

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597742
Total Pages : 505 pages
Book Rating : 4.41/5 ( download)

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Book Synopsis Recombinant Gene Expression by : Paulina Balbas

Download or read book Recombinant Gene Expression written by Paulina Balbas and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since newly created beings are often perceived as either wholly good or bad, the genetic alteration of living cells impacts directly on a symbolic meaning deeply imbedded in every culture. During the earlier years of gene expression research, te- nological applications were confined mainly to academic and industrial laboratories, and were perceived as highly beneficial since molecules that were previously unable to be separated or synthesized became accessible as therapeutic agents. Such were the success stories of hormones, antibodies, and vaccines produced in the bacterium Escherichia coli. Originally this bacterium gained fame among humans for being an unwanted host in the intestine, or worse yet, for being occasionally dangerous and pathogenic. H- ever, it was easily identified in contaminated waters during the 19th century, thus becoming a clear indicator of water pollution by human feces. Tamed, cultivated, and easily maintained in laboratories, its fast growth rate and metabolic capacity to adjust to changing environments fascinated the minds of scientists who studied and modeled such complex phenomena as growth, evolution, genetic exchange, infection, survival, adaptation, and further on—gene expression. Although at the lower end of the complexity scale, this microbe became a very successful model system and a key player in the fantastic revolution kindled by the birth of recombinant DNA technology.

Science and Social Context

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Publisher : McGill-Queen's Press - MQUP
ISBN 13 : 0773570276
Total Pages : 222 pages
Book Rating : 4.76/5 ( download)

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Book Synopsis Science and Social Context by : Lisa N. Mills

Download or read book Science and Social Context written by Lisa N. Mills and published by McGill-Queen's Press - MQUP. This book was released on 2002-05-28 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: She examines the decision-making processes at Monsanto that led to their making the drug available and discusses corporate, academic, and regulatory decision-making in the context of a restructured global political economy for agriculture. Mills shows that there was consensus about the scientific evidence but interpretation of that evidence differed depending on the context from which it was viewed. Scientists who analysed it for regulatory bodies interpreted it differently than scientists in corporate or academic institutions, and scientists in Canada and Europe interpreted it differently than those in the United States. In the United States it was assumed that any problems arising from its use could be taken care of within the existing dairy system; in Canada and Europe these problems were regarded as legitimate animal welfare issues. While all regulatory bodies agreed that human health problems were unlikely, in Canada the Health Protection Branch questioned this, but ultimately rejected the drug on animal health grounds.

Science and Social Context

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Publisher : McGill-Queen's Press - MQUP
ISBN 13 : 077352374X
Total Pages : 223 pages
Book Rating : 4.46/5 ( download)

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Book Synopsis Science and Social Context by : Lisa Nicole Mills

Download or read book Science and Social Context written by Lisa Nicole Mills and published by McGill-Queen's Press - MQUP. This book was released on 2002 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical analysis of the intensely controversial recombinant bovine growth hormone.

Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology

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Publisher : Springer Science & Business Media
ISBN 13 : 9401597499
Total Pages : 396 pages
Book Rating : 4.94/5 ( download)

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Book Synopsis Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology by : Otto-Wilhelm Merten

Download or read book Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology written by Otto-Wilhelm Merten and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: More then 20 years have passed now since the first recombinant protein producing microorganisms have been developed. In the meanwhile, numerous proteins have been produced in bacteria, yeasts and filamentous fungi, as weIl as higher eukaryotic cells, and even entire plants and animals. Many recombinant proteins are on the market today, and some of them reached substantial market volumes. On the first sight one would expect the technology - including the physiology of the host strains - to be optimised in detail after a 20 year's period of development. However, several constraints have limited the incentive for optimisation, especially in the pharmaceutical industry like the urge to proceed quickly or the requirement to define the production parameters for registration early in the development phase. The additional expenses for registration of a new production strain often prohibits a change to an optimised strain. A continuous optimisation of the entire production process is not feasible for the same reasons.

Life as Surplus

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Publisher : University of Washington Press
ISBN 13 : 0295990317
Total Pages : 233 pages
Book Rating : 4.16/5 ( download)

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Book Synopsis Life as Surplus by : Melinda E. Cooper

Download or read book Life as Surplus written by Melinda E. Cooper and published by University of Washington Press. This book was released on 2011-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the period between the 1970s and the present, Life as Surplus is a pointed and important study of the relationship between politics, economics, science, and cultural values in the United States today. Melinda Cooper demonstrates that the history of biotechnology cannot be understood without taking into account the simultaneous rise of neoliberalism as a political force and an economic policy. From the development of recombinant DNA technology in the 1970s to the second Bush administration's policies on stem cell research, Cooper connects the utopian polemic of free-market capitalism with growing internal contradictions of the commercialized life sciences. The biotech revolution relocated economic production at the genetic, microbial, and cellular level. Taking as her point of departure the assumption that life has been drawn into the circuits of value creation, Cooper underscores the relations between scientific, economic, political, and social practices. In penetrating analyses of Reagan-era science policy, the militarization of the life sciences, HIV politics, pharmaceutical imperialism, tissue engineering, stem cell science, and the pro-life movement, the author examines the speculative impulses that have animated the growth of the bioeconomy. At the very core of the new post-industrial economy is the transformation of biological life into surplus value. Life as Surplus offers a clear assessment of both the transformative, therapeutic dimensions of the contemporary life sciences and the violence, obligation, and debt servitude crystallizing around the emerging bioeconomy.