Receptor Data For Biological Experiments

Author : Henri N. Doods
Publisher : Taylor & Francis Group
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.85/5 ( download)

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Download or read book Receptor Data for Biological Experiments written by Henri N. Doods and published by Taylor & Francis Group. This book was released on 1991 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of the most relevant knowledge on classification, localization and biological effects of receptor systems and/or enzymes.

Author : Van Meels Doods
Publisher :
ISBN 13 : 9780745808567
Total Pages : 120 pages
Book Rating : 4.65/5 ( download)

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Download or read book Receptor Data for Biological Experiments written by Van Meels Doods and published by . This book was released on 1999-12-31 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Douglas A. Lauffenburger
Publisher : Oxford University Press
ISBN 13 : 0190283068
Total Pages : 376 pages
Book Rating : 4.63/5 ( download)

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Download or read book Receptors written by Douglas A. Lauffenburger and published by Oxford University Press. This book was released on 1996-01-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.

Author : Lee E. Limbird
Publisher : Springer Science & Business Media
ISBN 13 : 0387230807
Total Pages : 226 pages
Book Rating : 4.01/5 ( download)

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Download or read book Cell Surface Receptors written by Lee E. Limbird and published by Springer Science & Business Media. This book was released on 2006-06-02 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest. The study of receptors has changed considerably over the period of the publication of the three editions of this book. The cloning of several genomes makes it unlikely that preparations of receptors now or in the future will arise from their purification as trace proteins from native tissues, but rather from a myriad of molecular approaches. Nonetheless, understanding the molecular mechanisms and ultimately the in vivo biology of these receptors means that investigators will engage in molecular, cellular and ultimate in vivo strategies. It should be of value to investigators who want to identify, characterize and understand the biology of a receptor of interest.

Author : Jonathan W. Boyd
Publisher : John Wiley & Sons
ISBN 13 : 1119060265
Total Pages : 336 pages
Book Rating : 4.60/5 ( download)

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Download or read book Cellular Signal Transduction in Toxicology and Pharmacology written by Jonathan W. Boyd and published by John Wiley & Sons. This book was released on 2019-04-16 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques

Author : Vladimir M. Mirsky
Publisher : John Wiley & Sons
ISBN 13 : 3527632506
Total Pages : 506 pages
Book Rating : 4.03/5 ( download)

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Download or read book Artificial Receptors for Chemical Sensors written by Vladimir M. Mirsky and published by John Wiley & Sons. This book was released on 2010-12-20 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first to provide systematically organized information on all three important aspects of artificial receptor design, this book brings together knowledge on an exceptionally hot and multidisciplinary field of research. Strong emphasis is placed on the methodology for discovering artificial receptors, with both definitions for chemosensitivity as well as experimental setups supplied. There follows coverage of numerous classes of artificial receptors, including synthesis, immobilization on surfaces, and quantitative data on properties. The third part of the book focuses on receptor arrays for artificial nose and tongue applications and the whole is rounded off with an outlook and an appendix with all relevant quantitative data on artificial receptors.

Author : Lee E. Limbird
Publisher : Springer Science & Business Media
ISBN 13 : 1461312558
Total Pages : 251 pages
Book Rating : 4.50/5 ( download)

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Download or read book Cell Surface Receptors: A Short Course on Theory and Methods written by Lee E. Limbird and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.

Author : Mostafa Z. Badr
Publisher :
ISBN 13 : 9781493991952
Total Pages : 314 pages
Book Rating : 4.57/5 ( download)

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Download or read book Nuclear Receptors written by Mostafa Z. Badr and published by . This book was released on 2019 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering our understanding of these vital receptors and their role in numerous pathological conditions.

Author : Georges Vauquelin
Publisher : John Wiley & Sons
ISBN 13 : 9780470516645
Total Pages : 264 pages
Book Rating : 4.4X/5 ( download)

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Download or read book G Protein-coupled Receptors written by Georges Vauquelin and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provides a clear summary of the current knowledge in this fast-evolving field. The book sets out with an introduction to signalling molecules and their receptors, and an overview of the technical approaches used to investigate these interactions. Structural, functional and especially pharmacological aspects of GPCRs are then discussed in more detail and much attention is devoted to the analysis and interpretation of experimental data. The now widespread use of recombinant cell lies, receptor mutants and related artifices in drug research is critically evaluated. Special attention is also devoted to topical but often poorly understood concepts, such as insurmountable antagonism, inverse agonism and allosteric interactions. By combining general information with the major state-of-the-art concepts in GPCR-research, this outstanding book equips the reader with the necessary background for understanding and critically evaluating the current literature. Written by two experts from academia and industry, G Protein-coupled Receptors: Molecular Pharmacology offers a unique view of academic and applied approaches aiming to reveal new ideas in pharmaceutical research. The book is of interest to anyone involved in drug development and preclinical research and those who need to function within multi-disciplinary teams in the pharmaceutical industry: from investigators to product managers or clinicians who seek to have a broad mechanistic understanding of drug-receptor interactions. It is also an invaluable resource for final year undergraduate and postgraduate students in pharmacology and cell and molecular biology.

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 1483259706
Total Pages : 457 pages
Book Rating : 4.03/5 ( download)

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Download or read book Receptors written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.