Rat Experimental Transplantation Surgery

Author : Peter Girman
Publisher : Springer
ISBN 13 : 3319145592
Total Pages : 252 pages
Book Rating : 4.94/5 ( download)

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Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by Springer. This book was released on 2015-11-16 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into ‘General’ and ‘Specific’ sections. The ‘General’ section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant’s used in rat models, a description of basic surgical techniques and blood sampling. The ‘Specific’ section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe ‘tips and tricks’ including practical advice and recommendations.

Author : Peter Girman
Publisher :
ISBN 13 : 9783319145600
Total Pages : pages
Book Rating : 4.06/5 ( download)

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Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into 'General' and 'Specific' sections. The 'General' section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant's used in rat models, a description of basic surgical techniques and blood sampling. The 'Specific' section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe 'tips and tricks' including practical advice and recommendations.

Author : Arnulf Thiede
Publisher : Springer Science & Business Media
ISBN 13 : 3642616577
Total Pages : 412 pages
Book Rating : 4.70/5 ( download)

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Download or read book Microsurgical Models in Rats for Transplantation Research written by Arnulf Thiede and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preclinical experimental transplantation research that is based on microsurgical models in rats fulfills two indispensable conditions for modern organ transplanta tion research: Almost all organ grafts can be performed on the rat with an amount of technical effort that is still justifiable. Thus transplantation models that are analogous to human organ transplantation can be developed, tested, and evaluated. This fulfills a necessary condition from the standpoint of surgery. With the species rat, we have a great variety of genetically different inbred strains. From the immunological point of view this is an indispensable prerequisite for the investigation of preclinical transplantation models that can be expected to produce controllable, reproducible results. In vivo experimental results can be supplemented by and correlated to in vitro tests. Lately these experimental results are being greatly expanded and more precisely defined by the application of immunohistological methods that have been established recently in Kiel. In this book we hope to present a cross section of the microsurgical models in use today and of current immunological and immunohistological models. Furthermore, we wish to record the present state of microsurgical organ transplantation research and to show its relationship to the current state and development of clinical organ transplantation. A special aspect of our Kiel research group is the long-term, well-functioning, interdisciplinary cooperation between surgery, immunology, and pathology. Through this cooperation we attempt to provide an atmosphere in which theoretical and practical viewpoints can mutually influence each other.

Author : Wolfgang Timmermann
Publisher : Springer Science & Business Media
ISBN 13 : 3642721400
Total Pages : 655 pages
Book Rating : 4.03/5 ( download)

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Download or read book Organtransplantation in Rats and Mice written by Wolfgang Timmermann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Main focus of the new book will be the description and discussion of rat and mouse models for organ transplantation. Various microsurgical techniques will be presented which allow transplantation of functional organs in syngeneic systems. In particular, the extremely difficult methods necessary for organ transplantation in mice will be presented and evaluated. Besides these practical aspects the book will also cover the theoretical sides of organ transplantation like the immunobiology of allotransplantation. Special emphasis will be given to the resurgent field of xenotransplantation. The results from xenograft models developed in the recent years using rats or mice will be reviewed and their impact on future human xenotransplantation will be discussed.

Author : Naoshi Kamada
Publisher : CRC Press
ISBN 13 : 0429558651
Total Pages : 168 pages
Book Rating : 4.58/5 ( download)

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Download or read book Experimental Liver Transplantation written by Naoshi Kamada and published by CRC Press. This book was released on 2019-06-04 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, Experimental Liver Transplantation is a helpful guide through the process of Liver Transplantation and how the surgical techniques have evolved over the years. Filled with references to the history of Liver transplantation, to the experimental procedures performed on rats. This is an essential guide to any students of surgery or professionals in their respective fields.

Author : Huifang Chen
Publisher :
ISBN 13 : 9781626186088
Total Pages : 506 pages
Book Rating : 4.81/5 ( download)

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Download or read book Experimental Organ Transplantation written by Huifang Chen and published by . This book was released on 2014-05-14 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ transplantation is one of the best therapeutic options for patients with end-stage organ failure. Experimental organ transplantation is an important link between basic science and clinical practice. Both editors, Dr. Chen and Dr. Qian, have been working in this area for more than 20 years. Experts from the United States, Canada, China, Japan, Italy, Span, Turkey, Switzerland, Hungary, and Brazil contributed 25 chapters in this book, and provided detailed descriptions of techniques for vascularized organ allografts in mice, rats, pigs, and nonhuman primates, as well as detailed descriptions of non-vascularized pancreatic islet and spleen allografts. Furthermore, they discussed new advances in transplantation immunology. This book provides numerous important references which were carefully selected by the authors to extend their visions and knowledge. The appropriate readers of this book include medical students, graduate students, residents, surgeons, physicians and immunologists interested in the transplantation area.

Author : Michio Mito
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.63/5 ( download)

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Download or read book Hepatocyte Transplantation written by Michio Mito and published by S. Karger AG (Switzerland). This book was released on 1997 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly increasing frequency of organ transplantation is causing a severe shortage of donor organs. Hepatocyte transplantation has thus been studied to develop an alternative therapeutic method for patients with various liver diseases. In experimental studies using rodents, transplanted hepatocytes survive and function in ectopic sites for a long period of time. Recent advances in molecular biology and tissue engineering enable us to manipulate isolated hepatocytes before transplantation. Before clinical application of this new therapeutic method, there are many issues to be resolved such as determining an optimal location for transplantation, rapid proliferation of transplanted hepatocytes, transplantation in large animals, immunological reactions and long-term gene expression. In this book, authorities on hepatocyte transplantation from all over the world describe progress in this field and discuss the unsolved problems. For researchers and clinicians interested in the liver, this book will be the definitive resource on hepatocyte transplantation.

Author : Aksel Foss
Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.31/5 ( download)

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Download or read book Liver Regeneration and Partial Liver Transplantation written by Aksel Foss and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Sherif Amr
Publisher : BoD – Books on Demand
ISBN 13 : 1789230128
Total Pages : 190 pages
Book Rating : 4.23/5 ( download)

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Download or read book Issues in Flap Surgery written by Sherif Amr and published by BoD – Books on Demand. This book was released on 2018-04-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of flap surgery parallels the increasing complexity of soft-tissue defects needing reconstruction. Random and pedicled flaps as well as free muscle and fasciocutaneous flaps have helped to reconstruct single soft-tissue defects. The multiplicity of defects needing reconstruction and donor-site morbidity in addition to tailored reconstruction have called for a revision of flap concepts in favor of perforator flaps. Unfortunately, we are faced with increasingly complex reconstructive issues. New reconstructive techniques, such as the Ilizarov method, have made orthopedic reconstruction after high energy and complex trauma possible. Revision surgeries after tumor resection and plastic surgery have brought about soft-tissue defects associated with extensive fibrosis and necrosis. As a result, previously nonsalvageable limbs have been salvaged. The reconstructive surgeons are faced with the following situations: multiple soft-tissue defects, extensive fibrosis, possibility of major vessel loss, and possibility of damage of several perforators.

Author : Hesham Abdeldayem
Publisher : BoD – Books on Demand
ISBN 13 : 9535109650
Total Pages : 658 pages
Book Rating : 4.55/5 ( download)

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Download or read book Hepatic Surgery written by Hesham Abdeldayem and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Longmire, called it a "hostile" organ because it welcomes malignant cells and sepsis so warmly, bleeds so copiously, and is often the ?rst organ to be injured in blunt abdominal trauma. To balance these negative factors, the liver has two great attributes: its ability to regenerate after massive loss of substance, and its ability, in many cases, to forgive insult. This book covers a wide spectrum of topics including, history of liver surgery, surgical anatomy of the liver, techniques of liver resection, benign and malignant liver tumors, portal hypertension, and liver trauma. Some important topics were covered in more than one chapter like liver trauma, portal hypertension and pediatric liver tumors.